HsaINT0148430 @ hg19
Intron Retention
Gene
ENSG00000063015 | SEZ6
Description
seizure related 6 homolog (mouse) [Source:HGNC Symbol;Acc:15955]
Coordinates
chr17:27306698-27309057:-
Coord C1 exon
chr17:27308389-27309057
Coord A exon
chr17:27306832-27308388
Coord C2 exon
chr17:27306698-27306831
Length
1557 bp
Sequences
Splice sites
5' ss Seq
CAGGTCAGC
5' ss Score
7.16
3' ss Seq
TGTCTCCTCCTGCCTCCCAGGCC
3' ss Score
9.75
Exon sequences
Seq C1 exon
GACTCTCTTTAGAGGCCCCAACCGTGGGGAAAGGACAAGCCCCAGGCATCGAGGAGACAGATGGCGAGCTGACAGCAGCCCCCACACCTGAGCAGCCAGAACGAGGCGTCCACTTTGTCACAACAGCCCCCACCTTGAAGCTGCTCAACCACCACCCGCTGCTTGAGGAATTCCTACAAGAGGGGCTGGAAAAGGGAGATGAGGAGCTGAGGCCAGCACTGCCCTTCCAGCCTGACCCACCTGCACCCTTCACCCCAAGTCCCCTTCCCCGCCTGGCCAACCAGGACAGCCGCCCTGTCTTTACCAGCCCCACTCCAGCCATGGCTGCGGTACCCACTCAGCCCCAGTCCAAGGAGGGACCCTGGAGTCCGGAGTCAGAGTCCCCTATGCTTCGAATCACAGCTCCCCTACCTCCAGGGCCCAGCATGGCAGTGCCCACCCTAGGCCCAGGGGAGATAGCCAGCACTACACCCCCCAGCAGAGCCTGGACACCAACCCAAGAGGGTCCTGGAGACATGGGAAGGCCGTGGGTTGCAGAGGTTGTGTCCCAGGGCGCAGGGATCGGGATCCAGGGGACCATCACCTCCTCCACAGCTTCAGGAGATGATGAGGAGACCACCACTACCACCACCATCATCACCACCACCATCACCACAGTCCAGACACCAG
Seq A exon
GTCAGCTACCTGCTGGCTTGCAGATGTGGAAATGGGGATGGGGGAGGCTGCGGGGCCCCTAAAAGCCTGTCTCTGACACTGTGCCAGCCTGCCCTGCCCTTTGGCACCAAGGGCCAGCCTGCAGGAGGCATGTAGATTGGACCCAGATAGACCTGAGCTCAAATCCTGATTCTTCAGCCAAGTACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCAGAGGCCAGTGGATCATCTGAGGTCAGGAGTTCAAGACCCTCCTGGCCAACATGGCGAAACACCATCTCTACTAAAAATACAAAAATGAGCCGGGCATGGTGGTGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTCAAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCACCATTGCACTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTCAAAAAAGAAAAAATCTTGATTCTTCCAACTATAACATGACCCTAGGAATTCTATTTAACATCTCATCTCTGAGCCTCATCTGTAAAATGGCAATAAGAAAATAAACTTCTGGCTGGACACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGACATCAGAAGTTCAAGATTAGTCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTGGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGTGTGGAACGAGGTCAGGAGATCGAGACCACCCTTGCTAACACGGTGAAACCCCATCTCTACTAAAAAATACAAAAAATTAGCCGGGCGTAGTGGGGGGTGCCCGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGTCAGAGCTTGCAGTGAGCCAAGATCATGTCACTGCACGCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCAAAAAAAAAAAAAAATAGCCAGGCATGGTGGTGTACACCTGTAATCCTAGCTACTCGGGAAGCTGAGCAGGAGAATAGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCACGCCATTGCACTTCAGCCTGAGCAACAAGAGTAAAACTCCGTCTCAAAAAAAAAAAAAAAAAGAAAGAAAACAAACCTCATTGAGCTACTGTGAAAACTGAGATAAGATTGCACATGTTAGGGGGCCGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCGGATCATGAGGTCAGGAGATGGAGACTATCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAAAAAAAAAGATTGCACATGGTAGGTGCCTAATAAAAGGTGGTCCCCTTCCTTCAACAGGAGACTAGACATCACAAGAGGTGGTCTTCACCACACACACACACACACACACACACACACACACACACACACACACGGTTCAGCCTTAGTTGGACCACTTCACCAGAGCTGGCACTAGCTTTGTGTCTCCTCCTGCCTCCCAG
Seq C2 exon
GCCCTTGTAGCTGGAATTTCTCAGGCCCAGAGGGCTCTCTGGACTCCCCTACAGACCTCAGCTCCCCCACTGATGTTGGCCTGGACTGCTTCTTCTACATCTCTGTCTACCCTGGCTATGGCGTGGAAATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000063015-SEZ6:NM_001098635:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.906 A=NA C2=0.467
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGGAGATAGCCAGCACTACA
R:
GCCATAGCCAGGGTAGACAGA
Band lengths:
342-1899
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)