HsaINT0149321 @ hg19
Intron Retention
Gene
ENSG00000109686 | SH3D19
Description
SH3 domain containing 19 [Source:HGNC Symbol;Acc:30418]
Coordinates
chr4:152049322-152053535:-
Coord C1 exon
chr4:152053483-152053535
Coord A exon
chr4:152049509-152053482
Coord C2 exon
chr4:152049322-152049508
Length
3974 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
3' ss Seq
CACCTCTAATTTGATAACAGGTT
3' ss Score
4.68
Exon sequences
Seq C1 exon
GCACAAAGGTACCACTGAAAACCAAAAAAGAAGATTCTGGCTCAAACTCTCAG
Seq A exon
GTAGGCTGCTTGAACAGATGACTATAGTGACAGCCAGGTTCAGACTCTGGGAGGAATATTAAAATCATAATTTTCAAGAGAATATAGTATGAATTAATTTTTCAATTCATACAACAAATGTTTGTAATAAATTCTTAGATGGTTAATATATTTTATATAGAGAGCTCATACAAAAACATGTAAACCCTGATAGAAAATGAAAACAGAGACTGGGCAGAGTGGCTCATGCCTGTAATCCCAACACTTTGGGAAGCCAAGGCAGGTGGATTACCTGAGGTTAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAACCAGGCATGGTGGCGTGCACCTGTAGTCCCAGCTACTTGGAAGGCTGAAGCAGGAAAATAGCTTGAACCTGGCGGTGGAGGTTGCAGTGAGCCAAGATAGCACCACTGCATTCCAGCCTGGGTGGCAGTGCGAGACTCTATCTCAAAAAAGAAAGAAAGAAAATGATAAAAGAGACATGATTAGAGAATTCATAAAAGAGGCTGTGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAAGCCGAGGCGGGCGGATCATGAGGTCAGGGGATCGAGACCACCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAAATCAGCCGGGTGTGGTGACCAGCGCGCGTATTCCCAGCTACTCAGGAGGCTGAGGCAGGGGAATGGCGTGAACCCGGGGGGCAGAGTTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCCGCCTGGGAGACAGAGCAAGACTCTGCCTCAAAAAAAAAGAAAAAAAGAAAAAAAGAATTCATAAAAGAGATACCATAAGTGGCTAATATTGAAAAAATATTTAACCTTTCTAATAATCAAGAAAATATATAATAAAGCAGCAATAAAATACCATTTAACCTATTCAGTTAACAAAGATTCAGTGCAGCTCAGCACTAAACAAGCAATTATAAGCATGTGAGTGTTAAAAAAAAAAGAGAGAAAGTACACATTCTTATTTGTCACCCTAAGAAAAGGATAAAAAATGAGATAGGGTTTTAGTCACAAAGATGAGCATAGTGCTAATATAATAAGAAAAAATTGGAAACAACCTAAATATGACCATTATTGGGAGAATATTCTAAAGCTATGAAAAACTAGATTTATCAAATAAAATAATGTTTTTAAATGTCATGAGAGGAAACATAGGGAAAGGGGATATAAAATTGAATATATAGCATAAAAAGACTGGAAGGAAATTATTCAAGTTACTAGTATTAAATTGCATCTAGGTAGTGAGATTATATATACGGGTAGGTTTTTTTCCCCCACTTCTTTTTTTTTTTTCTTTTTTTTGAGACGGAGTCTTACTCCGTCGCCCAGGCTGGAGTGCAGTGGCGCAGTCTTGGCTCACTGCAACCTCTGCTGCCGGCTTCAAGTGATTCTCCTGACTCAACCTCCTGAGTAAGCTGGGTTTACAGGTGCCTGCCACTGTGCTTCGCTAATTTTTGTAGTTTTAGCAGAAACGGGGTTTTACCGTCTTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGATCCACCCACCTCGGCCTCCCTAAGTGCTGGGATTACTGGCATGAGCCACTGCGCCTGGCCTTCTCCATTTCTTTATACGTTTCTCAACTTTCCAAATATTTAGGAACATTTGTTTCATTTGTATAATGAGAAAGAGAAAAATAGTGGGTTAAAATTTTTACACTGTTCAGCATGACCCCAGAAATGCTTAAAGGTACTAGGAATGTGGTGCCTTCTGTTGTTTTTAGTTTTTTGTTGTTTTTGGTTTTATTTTGGTTTTTTTGTTTTGTTTTGTTTTGTTTTTTTGAGACAGGATCTCACTCTGATGCCCAGGCTAAGTGCAGTGTCGAGGTCTCAGCTCACTGCAACCTCTGCTTCCCAGGCTCAAGCAATCCACCTCAGCCTCCTAAGTAGCTGGGATGACAGGCACACACCACCACTCCCAGCTAATTTTTGTATTTTTTGTAGACAGGGTCTCATTTTGTTGCCCAGGCTGGTCTCAAAATCCTGGGCTCAAGCGCTCCACCTGCCTCAGCCTCCCAAGGTACTAGGATTACAGGGGTGATCCACCACATCCGGCCTTCCATTGTTTTTTGTGACAAATTTAGAAGAGTTAAGCCTGATGGGATCATTGTGTTTGTGAAAATGTCACTTGTAATTGGCCTGTGTGTCCCTTAATTCTTTATCCCTACCCACTGATAAAGTGAAACAGGAAGGAAACTGACTACAGTTCTCCAAAAGGAAATGTTCACATGGTTGTTGCCTGCATTTTTGGAGAATGATAAGTTCCATCCTTTAGGGTTGGTTACTCAAGTGCAGGAGCAAGAGGGGGTTAGTGTTGTTTGCTTGCTTTTTGTTTTTGTTTTATAAGCCATCAGTTATTGAGCACTTAAGATGTGCCAGGCACTGGGCTAAATGTTAGACATGCATTGTCTCATTTAATCCTCTTAGTAACCCCAAGATGAAGCTGAGCCTCAGAGAAGAGAAGCGTCTTGCCCAGTGTCACGAAGTTAAGAAGTGGCAGAACTGGGTCTGGAAACCTTGCCTGTGTAGCTCCAAAGCCTTTGTCCCGGCCAGGCGCTGAGGCTCACTCCTGTAATCCCAGCACCTTGGGAGGCCAAGGCAGGTGGATCGCTTCAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGTGCACCTGTAGTCCTAGCTAATCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCATTGAGCCAAGATTGCATCATTGCCCTTCAGCCTGGGCAACAGAGCGAGACTCCATCTCGAAAGAAAAAAGCCTTTTCATTATCCTCTACTGCCTTCTTGAGCCTCTTGAACATAGGGTTCCCATCCCAAATTGGCAGAGCTGCCTCTTCACAGAGCAAAACCTTTCTCTAATGTGCCTGGGATAAAAGTGTTCTTACACTAGCCCACCACATCTGGGTGTTATCCTGCCAATCTTAGAGTTAACTACAGCTCATAAAATTAAAAGTGTGAATTGATGAAGTTCTGTGCTATGGACTCTAATTGTCTCTGAATCAAGTAAAGACCTGGGAATTCATAGACCAACCCATTCTGATCCTTCCTAATTTAAATAAAGAAGAGCTTCACTGATAATTACATACTTTATCAGAATTTTTTCATAGTGTCAAATACTATGCATAAATATTTTATGCTTTTACCTAATTCTTTAATATAACAATATAATAGGTCATATTAAGAAAAAAGTTTTTTGGCTGAGTGAGGTGGATCATGCCTGTAATCCCAGAAGTTTGGGAGGGTGGGAGGATCACTTGAGCCAAGAGTTCAAGACCAGCCTGGGCAACATAGTGAGACTTCATTTCTGCAAAAATAAAATAAAATTAAATAGCCGAGTGTGGTGGCTGCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGAGGGAGGATTGCCTGAGCCCAGGAAGTCAAGGCTGCAGTGAGCTATGATTCTGCCACTGTACTCCATCCTGGGTTACTAAGTAAGAACTTGGCTCAGAAAAGAAAATAAAGAAAGTAAAAAAGTGTTTGCTTAAGCTTTGTATATCCCTTAAAAGCAGAAAAGCCACAAATTCTATCACACTTGTCATTTAGAGTTATAATTTAAGAAAAAATTATTGGAAACTTTTACTTCTGAAACTTGATAGCAACATAAAGTATTAGATAATTTAAAGAAGCCTTCAGGCTTTGAAATCTTAAGACCCCTTAGTTTTTTTTTCCCCACTACTTTTTAAGCTTTGTAGAACTCAATTTCAAATAAAATCTTACACTTCTGACCACACCTCTAATTTGATAACAG
Seq C2 exon
GTTAACAGTCTTCCGGCAGAATGGTGTGAAGCTCTTCACAGTTTTACAGCAGAGACCAGTGATGACTTATCATTCAAGAGGGGAGACCGGATCCAGATTCTGGAACGTCTGGATTCTGACTGGTGCAGGGGCAGACTGCAGGACAGGGAGGGGATCTTCCCAGCAGTGTTTGTGAGGCCCTGCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109686-SH3D19:NM_001128924:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.500 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0001823=SH3_1=WD(100=73.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)