HsaINT0149327 @ hg19
Intron Retention
Gene
ENSG00000109686 | SH3D19
Description
SH3 domain containing 19 [Source:HGNC Symbol;Acc:30418]
Coordinates
chr4:152060927-152065202:-
Coord C1 exon
chr4:152065062-152065202
Coord A exon
chr4:152061000-152065061
Coord C2 exon
chr4:152060927-152060999
Length
4062 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGG
5' ss Score
7.34
3' ss Seq
AGCCCTTTTCTCCCCCTAAGGAT
3' ss Score
7.84
Exon sequences
Seq C1 exon
CGTGGGGATGTACTTGTGATGCTGAAGCAGACGGAAAATAATTACTTGGAGTGCCAAAAGGGAGAAGACACTGGCAGAGTTCACCTGTCTCAAATGAAGATTATCACTCCACTTGATGAACATCTTAGAAGCAGACCAAAC
Seq A exon
GTAAGGAATTAATATTGTTACAGCCCTCATATCACACATAGCAGCACATTTCATGGAACTATTAATTATATCTCATCTTCAGGTTTTTATTAGCACATTTATTTTAACCAGAGTAAAAATTACAGTAGCATTTATTCTACTTTTAGAATAAATTACTACTAAGAGACTTGCCACTGCCATACTAATCACTTCGATACAGAGTGACTACCCTGTGTTTTGTTTTCTTCACTGCACTCCAGCCTGGGCCATAGAGCGAGATTATGTCTTGGAAAAAAAAAACAAATAAAAAAATAAAGTAAATATGAAAAATAATAGTGATCAAGTAAAATACTTGGTTTGCCGTTTATCCTAGTTTTCATAATCTTTTCCCATTTTTTCTTCTTAGAAGGCAGTTTATCTTTTGAAGTTTGCTAAGAAACTAAAAAATTGTATTTGGAGAGCAGAGGAGATATGTGTTAAGGTAGCTTCTGCTGGCATATGAAAATCCTTACTTTAGCTCCCACGGGGCAAGTTCTCCACTGACTCATTTTCTCTGTTTTGGTACGGCATTATCCATCTGTCATAGCTGTCCTTCCTCTTTCAGAACACACTTATGGCAACAGTGGAAGTTATACTGCCAAAAAGCTTTCCTTTGTGAAAAATAGAAGCTAAAAAAAATTAGAATTTTTTTTTTTTTTTTTGAGATAAGGTCTCACTCTGTTGCCCAGGCTGAAGTGCAGTGGTATGATCACTACAGCCTTGACCTTCCCGGCTCAAGCAATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGTGCACCACCATGCCTGGCAATTTTTAAAATTTTTTGTAGAGACAGGGTCTCACTATGTTGCCAGGGCTGGTCTGAAACTCCTGGGCTAAGCCATCTGCCTGCATGGGCCTCCCAAAGTGTTCAGATTACAGGTATGGGTCACCATGCCCAGCCAAAAGTTAGTCTTTTATAACAGTGCAAAGTTCTTTCCACCTTAAATACCACCTTCTCATCTTTTACTATAGACTTGCAGAGAGTTGGCCTCTGATGGGCAGCTATTGGTGATAATGAAATGAATCCTCCTTTATGCTTCTGGGTTCATGGCTATTGTTACATTTTTTTTTTAAATAAAACTTACCTATTTGAAAGCCTAGTTTTAAGGTAAATATCTCTACGAATATGTTGTACTTTGCCCTAACTTGGCAAACAGAAAATATTGAATGAACATGACCAGTTGTGGTTGAATCAGACAGATCATGGGAAAAGTGGAAGGTTGTTGCCTGGTACATGGTTGAGACCCCAGACCTGGGTTTCAGGGAAGTGGAATTTGGTTCCCCTTCCACCTTCTTCGGTGGTTATTTAACTTCTCTAAACTTTATTTTTTTAATGTGTGAGATAACTGCCCACAGAGTTGTCTTCAGAGTTGACAGATTATATGATGTTATTTGTGTAAAAGTCCAGAATAGATAAATCCATAGAGACAGAAAGTAGACTACTGGTTGCCTGGGGCTGAGGGGAGGGTAACTGGGGTGTGACACCTAATTAGTAGGAGGTTTCTTTGGGGAGTGATAAAAGTGTTCTGCACTTGGGTTATGGTGATGGTTGGATAATTCTATGAATATGCTACAGCCATGTTCACTTTCAGTAGGTAAATTTTATTGTATGTGGGTTATATCTCAAAGATGTTTAACAAATTCATTGAGCTAATGCATATAAGGTATTTAACACAGTGACTAGCACATGGTGAATGAGCAGTAAATATTAGCTATTCTTAATATTACAAAACCATTTGCATTAGCAGTTATAGTCATATTAGAAAGACCTTTGCATTATGTTATATTTACCTACCAGATACCTACCCCAGTGGTATGGTCTGAATTGTATGGACCACTTGTTGGCAACCCTGTCTAGCCTGTTCCTCTTGCCCTTCACCTGCTAGGCTGGGTTGATGAGCAGCATTGCCAGTGATATCCATACACTGAAGGCAGAGAAGGGAAAATGTGTGACTGGGAGGCACAAATTATCCCCTCCCTCCAAGGACTGGTTTATGTTTAGGCCTCTGGTCCATTTGGAGATTTCATGTTTGTGTTTGGTGTGTGGTAGGTCTCTGACATCATTTTTTCCAAATGGATAGGCATCTAGCCTAATAACACTTATTGAATAGTAATTCCTTTTTCTCCACAGATGTAAATCAGAAAAAAATGAAAATCACACATGCACATGTATAACACATTATATAAATAATAATTAATTTGTTTAACTTTTTTTGGAGAGAGTCACTCAGTCATCCAAGTCAGAGTATAGTGGCACAATCATAGCTCACTGCAGCCTCGAGTTCCTGGGCTCAAGAGATCCTCACACCTCTGCATCCCTAATAGCTGGGACCACAGGGGTGTATCACCATGCCAGGCTAATTTTTTATTTTTTTGTAGATATGGCATTTCTTATGTTGTCCATGCTGAATAATTATGAAAAGCCACTCCAGGCTGGGCACGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCCAAGATGGGTGGATCACCTGAGCCCAGGAATTTGAGACCAGCCTGGGCAACGTGGCGAGACCCAATCTCTACAAAAAATACAAAAATTAGCCAGGCATGGTAGTGCTTGTCTGTAGTCCCAGCTACTTTGGGGACTGAAGTGGGAGGATAACTTAACCCCTGGAGGTCAAGGCTGCAGTGAGCTGTGATTGTGCCACTACACCACAGCCTAGGTGACAGAGCAAGACCCTGTGTCAAAGAAAAAAAAGCCATGTCAGACCTAAAATATCTCAGAATTCATGAAATTTCCATATTGTTCATTTATTTAGAGAAAAGCATTAAGCAGTCCATGAAAAAATGTTAGGGTCTTCTTAGTAAGCTAATATAGTAAGCTACATTAGCCATTAGAGTCTTAAGTTATATTTCAGTTTACCTAACTTGAGAGAATGAAAGTTTTGTTTCTGCAGGTGCATTTTGGTTGAAAGAGCAGCTGAGATTTAGAAAAGATCTCAGCAAAGGTGCTGCAGGGTTGAAATGGAGAAAGTGGACCATCATTCACAGTGCGCTGCAATCAGCCTGGTGCATCATGGCCAGGGGAAGGGCAGAGGTATAGATGTGTCAGGACGTCTCTAAGGGGACAAGAGTTATTAGAGGAGGTGAAGAGACAAGAAAGGGCACAAAAATCTGCCTTTATTTATTTCACAGGCTTGCCAGTGTTGAAGAGTGTTAAGTTATAACTCCAAATAATATCCTTCAGTGGGATTTGATGATGATGAGGATAAGCCTGTCTCTTGATATAAAGAAACTAAGAATAACAATTGCTAGTCAATAAGAAGAGGTCGCTCTTCAGCTTTGCCTTATCCTCTGGCCAATCTCGGCATTTGGCTAGATGGATAGAGAATGTTAGATTCTTTTTGCTAATTTATTTAGAACTACTGTTGAATAAACCATTCAGATTAAATACAAAATGCAGACCAGGCATGGGAGGTAGCATTGCTTTCAAATTAGAAAAAGCACTTAGTTAAGTGGTAATAAATGAAATGGATTTTACTTTTTGTGAATTATACTTCTGTTGAAAGTCATTAGCTCCTTTCATTACAAAAGGCAAGAGCATAAATCATAGAACTTTCTTCTTTTCCCATCCTAATAAAGACACAACTTTTAAGACTCTGTCTTGATCACAGTTTTAAGGAAAAAGCTATCCTTGAAAGGGAAAGAGGTCAAAAACCACTACTTTGGGGTAGAATAGATACTGTTTCAAAATAAATAAACAGTTCCCTTTTGTTTTACTCTCTCAGCTTAAAAAAGCAAAAAGAAAACATACTGGGGGATATTTTAATTGAGATTTTCATCCTCCCTTAGCAAGGACACATTCTTCTTCAACTTGATAATAATTCCCTTGTTTGGCTCAACTGTGTGGTTTGCATCATGTACTCATAATGTAATTGTGTCAAGAGGACTCTAATGAGAAAAAAAAAATTGGTCTCAGAGTGAATAATAAATCCACCATCTATCCTGCACACTTCATTCACAGCCCTTTTCTCCCCCTAAG
Seq C2 exon
GATCCAAGCCACGCTCAGAAGCCTGTTGACAGTGGTGCTCCTCATGCTGTCGTTCTTCATGATTTCCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109686-SH3D19:NM_001128924:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.518 A=NA C2=0.462
Domain overlap (PFAM):
C1:
PF0765312=SH3_2=PD(63.0=72.3)
A:
NA
C2:
PF0001823=SH3_1=PU(17.4=32.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)