HsaINT0167543 @ hg38
Intron Retention
Gene
ENSG00000198586 | TLK1
Description
tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]
Coordinates
chr2:171011373-171014948:-
Coord C1 exon
chr2:171014851-171014948
Coord A exon
chr2:171011455-171014850
Coord C2 exon
chr2:171011373-171011454
Length
3396 bp
Sequences
Splice sites
5' ss Seq
ACAGTAAGT
5' ss Score
9.49
3' ss Seq
TTTTTGCCCCCACCTCTAAGGTT
3' ss Score
7.65
Exon sequences
Seq C1 exon
GAAGAGGCAGAAATCCAGGCAGAACTTGAACGTTTGGAAAGAGTCAGAAATCTTCACATACGTGAGCTGAAAAGAATAAACAATGAAGATAATTCACA
Seq A exon
GTAAGTCATTATTTGCATTTCACAGTTTCATATTATTAAAACTACCCCCGCCCCCCATAGAGCATAAACACAATATTTCCTTCTTGGGTTGTCTCATCGTACTTAGAAAAGATCCAAAGTCCTTCCCATGGCTTGGAAGGCCTTTTATGATTTGGTCCCTGGCCACCTTACTGTCCTCACTTCTCTTAAACATGTCAAGAGCATTCCCTTCTCAGTGGGCTTTTGTGCTTACCATTTCCTCTGCCTGGATGTTCCTCCTCTAAACACCTAATTGGCTTAATTACTTATCTCACTCCAAATGTTCTTTAGAAAGGCCATTCTTAGATCATCCTATTTAAAATAGTAGTCCCTAGCCAGGCCCAGTGGTGCTCACCTATAGTTCCAGCTACTCAAGAGGCTCAGGTAGGAGGATTGCTTTGGCCAGGAGTTCAAAACCAGCCTTGTCAACATAGTGAGACCCCCATTTCTTTAAAAAAAAAAAAAGTCTCTGCTTCTTCATTTCCTCTTTTAATATCGTTACCTTGCTTTATATTTTCTGGATGTTGATCACTATCTGGAATTATAAATTTATTTTTTAGTTATTATTTGTCTCCTCCCTCTAGAATGTAAGCTTCATGAGTGCAAGGACTTGGTTTTGTTCTTGCTGTATCCGTAAAGCCTAGACCAGTGCCTGACATATGGCAGGCACTTAATAAATATTTGAATACCAAAGTTAATGTTATAGTAGTGAAGGAGAAATTATTTCAACCAAAAGTATTTCAGTAAGCCATGTATCCCACATTATGCAAGAATTGGGAGAGAAATGGAAAAGTACAGCTTACAGTCTGTGTTCTTAATCAGTTGTCAGAATGAGTGCCATAGATAGTATATGTTGAAGCAATTGAAAGAAAAGAAAATATCTGTGGGCTTGTGGGAGCTTCATGAAAAAGATAGAAATTGAGCAAGACATAGAAGTAGAAATTAAGCAAGGTACTACTTGGATTTAGTTGATGTACAAGAGAGGAAAGGTTTCTGTTTACACTTCATCTTTGACTGGTCATGTAGTTTAAAGCTTCATGAGTTAATATAAGTATCAGAATAGGAAGTGGCCAATTTCTGTGTGAAATATGAAAATCTTGCTTAGAAAGGTCTTCTTGTGATGTCTATGTATGTATAATTCATAAATACACAGATCATTCCATTGTGTGAAGAGAAAGAAATAGTTATGGAATAACCTAAATTATGTCAGATTAAAATTCTAATGAAAGCCAGGTGTGCTGGCTTATGCCTGTAATCCTTGCACTTTGGGAGGCCAGTGCAAGCAAATTGATTGAGCCCAGGAGTCAAAAACGAGCCTCAGCAAGGTGGAAAAACCCTGTCTCTACAAAAAATACAAAACTTAGCAGGGAATGGTGGCATGCACCTGTAGTCGCAGCTACTTGGGGAACTGAGGAGGGAGGATCGCCTGAGCCTGCAGTGAGCCTAGATCGCAGTCCAGCCTGATTGACAAAGTGAGACTTTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAAAAGTGAGGGGCCAGGTGTGGTAGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCGGATCTCTTGAGGTTAGGAGTTCGAGACCAACCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATAAAAACACTAGCCCAGCGTTGTGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTGTCTTAAAAAAAAGTGAGACTCTGTCTCCAAAAAAAAAAAATCTAATAGAGCATATGGTACAAAACTAATTTAAGACTAACTGTTCCGAAAATTACATTTCAAATTTTGTGGATCTGACTTACATTGATGAAAATAAAATCAACTGTTACAGCTTTACAGTGTGGCTTGAAACTAAGCAGAAATTTCTTATATCTACAAGTTTCTCAAGAAAAAGCTTAAATTACTAAATCTAGAGTCAATTGATCTTGAAAAAAATAATAAAATACAATGTATTTTGGCCAGGCGTTGTGGCTCACACCTGAAATCGCAGTACTTTGGGAGGCCGAGGCAGGCGGATCACAAGGCCAGGAGTTTGAGACCAGCCTGGCCAATATGGTGAAACCCCGTCTTTATTAAAAATACAAAAATTAGCTGGGCGTGGTGGCACATGCCTATAGTCTTAGCTAATTGGGAGACTGAGGCAGAAGAATTGCTTTAACCCAGTAGGCAGAGGCTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCAGAGCGAGACTCTGTCTCCAAAAAATAAAAAAATAAATAAATAAATAAAAATACAGTGTATTAGTATTGCAAAGCTGACTTTTTTTTTGAAAGTGTACATTTTGGAACCACATTTTTCTGCTAAGTCCTGCCTTTTATTAGCTGTTAAGCAAGTTACTTAACTTTTCTGTGCATCAGTACCTTCATTTATAAAACAGACATAGTTATAGGACCTACCTGATAGGGTGGGTTGAAAACTAAATGAGTTAATACAGGTAAGAGCATAAAACGCACAAGTTGAACATCCTAATGTTGGAAATCTGAAATGTAAACTTCTCTAAAATCTGAAAATTTTTGAGCACTGACATGACATTCAAAGGTCTTGCACAAAGGAAATGCTCATTGGAGCATTTCAGATTTTGGATTTTCAGATTAGGGATGCTCAGTCGGCAATATTCTAAAAAAAAAAACAACTCCCAAATCGGAAACACTTCTGGTTCCAGGTATTTCAATAAGGGATACTCAGCCTATATATGGCAAGTACGGTAAATTTTAAGTAGTAATAGTAGTAGTATTACCTATGAGTGATTTTTTTTTTAATTTTAAAAAATCTTTTTAAAATTGGTGGTTAATTTATTTTACAAAAGTCCGAAGACAGTAAAATTTAATGATGAAGGCCAGTTTATAATTATGTTTAATCATATGTCAATACTGTAAAAGCTTGATTATAACTCCCAATATAAAAGTCTGTTTTTTCCAGAGAAGTGATTCTTGCTGAGTACATAAAGGATTTTATGAAGCTCTTGGCAATGCAGTAATTATTAGGTCTTTGTGAGAGTGCTATAATTGGTCATTGCTCCTGAATATTGAGCTATAAAAGTTTTGTGAGCGCCAAAGCCTTAAGATGGGTGGTAGTCATGCAGATAGACTGGTAGAGAATGAAAAGAAATATTGAATGAAATTTGAAATTAGCAGTGGAGTAACTGAGAAATAAATAGCTAGGAATAGAATAAGAGAGTAGAACTTCAGTGTAGAAGGAATTTTTATGTGTGTGTTTTAATATGTCTGTTTTTTGCCCCCACCTCTAAG
Seq C2 exon
GTTCAAAGATCACCCAACATTAAATGAAAGATATTTATTACTTCATCTGCTTGGTAGAGGTGGCTTTAGTGAAGTGTATAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198586:ENST00000431350:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.182 A=NA C2=0.107
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0006920=Pkinase=PU(5.7=57.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains