HsaINT0167554 @ hg19
Intron Retention
Gene
ENSG00000198586 | TLK1
Description
tousled-like kinase 1 [Source:HGNC Symbol;Acc:11841]
Coordinates
chr2:171912981-171914707:-
Coord C1 exon
chr2:171914661-171914707
Coord A exon
chr2:171913077-171914660
Coord C2 exon
chr2:171912981-171913076
Length
1584 bp
Sequences
Splice sites
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
3' ss Seq
TTCCTTTTTCTTTTACTCAGTAC
3' ss Score
6.84
Exon sequences
Seq C1 exon
GAAAAAGTATTGGGGGACGTGGCCACAAAATTAGCGACTATTTTGAA
Seq A exon
GTAAGTTCATTGAGGATTGTCTCCATTTCCTAATTCAGTACTATTCTGCTGTGAGCTAGAAATAATTTCTTAGAAGCACAAGGTCAGCTTTTGATTACTTACTTGATTAGAGCAGAGCTTTATTACTATGTGATATCTTTCTAGGAAAATTAGATTTACATTTACATTGGGATGCCATATCATTTTTTTCTAAATACTTTCTCACATAGTTGTTTATAATAACCTGTAAGATAGGCAAAATACATATTAGTGTTTCAGTTTACAGATGATGAAACTGAAGACCAGAAATGTAAAGTAGCCTACACCGTAATTTTTTGAATTTTTGCAGTCAGACCGTGGCAGCAGTGACCTTGAGCAATAATAGAACACTAGGCATAAATGGGTTAACCCATTTAAGGCAAAGTCTGAATTGAAGAGTAAAGAATAGAAGTTAAAGTTCACTGGCTCTCTAGTTGAGAATTCTTTCTACTATCAAGTGTAATTATTAAAACAACAAACATGGTCTACTCAATTGAAAAATATTTATGTTTACTTGAGAGAGCAGAATTGGCTGATTAAGGGAAGGACTGATTTTTTTTTCCACCACTGCTTTCTTTCTTGGGTTCGTAAAATCTAAAGTAAAGCAGTTGCTGACCATGAGATACCTGATGCTCTTTGGTTGAGGTCAGTCACTTACTGATATCATTAATTAAGAACCTTTGCCAAAGGTACGATGAATTCAAATCAACAAATGTCTCTTGAATGCCTACTATGTGCTAAATTTTATGCTAGGCTCTATTGATAAAATAAATAAGGCAAAATCCCTAGGTTGCAGGAAGTTGTTTAATGAACATGCTGGGAAGTTCCTATCTGTGCTGTTCATGTAAGTAAAGTAATTAAACAAGAAATGATGAAATGGACAATAATCTACACCCCCAGAGGAACTTTGCTGCAGCAAGTTATTTTCTTTTCCCATCCTTCGTATGTGAACTTGAAATAGGAGAAAAGATAGCTATGGAATAGATCAGTTGGCTTCTCTTCATATGCAGCTAAGTCATGCACTTTGTACAGAAGAATTGATTTTTTAAAGATTTTGTGCTGTTAGAGGGAAGGGACCTATTATAATTCTTTTTATATAGTGCCATGAACACTTGGGTATCTTGAGAATGATATTCTGTTTAAAATAGTTGATTATGTTCACTAAGGTCTATGGGTAAACATTTTGAAATTTCTTGGGATTAGGGACTATATGGCTCAATAAACATTTGTAGGGGACCTGTGCTAAGATTTGGGGGGAAAACAAAATATGTTTATTGCTTTGGAGGAATTTATTTGTCTTTGAGTTGACCAAAATAACAGATGATAGTCAGAATATAGAGTAATAAGGATCTTTATAAAACAGTCTCGTCATGTTCTTGTGATCAGTAGTCTCTTAGTCTTTTAGGACTTGGCTGACCTTGTGTTTTTTTTTTTTGTTCTGGACCCATTTAAATGACTACTTATTTTAAAATTAGGTATATTTAGATTAATTCTTAATGTCATATCTGAAATAACTGTCTGAGCCTGCTTTAGTAAATAATAATGCTTCCTTTTTCTTTTACTCAG
Seq C2 exon
TACCAGGGTGGAAATGGCTCAAGTCCAGTAAGAGGCATACCTCCTGCAATCCGTTCTCCTCAAAATTCACATTCACATTCCACTCCTTCCTCATCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198586-TLK1:NM_012290:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.969 A=NA C2=0.988
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)