HsaINT0172231 @ hg19
Intron Retention
Gene
ENSG00000121060 | TRIM25
Description
tripartite motif containing 25 [Source:HGNC Symbol;Acc:12932]
Coordinates
chr17:54985829-54991409:-
Coord C1 exon
chr17:54990753-54991409
Coord A exon
chr17:54985925-54990752
Coord C2 exon
chr17:54985829-54985924
Length
4828 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
3' ss Seq
CTCATTTGTTTTCCCTGCAGGCC
3' ss Score
11.64
Exon sequences
Seq C1 exon
GTTTCCTCGGCGGCCTCGGAGCGCGGGTGCAGCAGTTGTGTCCCGACCCCTGGGAGCGCCATGGCAGAGCTGTGCCCCCTGGCCGAGGAGCTGTCGTGCTCCATCTGCCTGGAGCCCTTCAAGGAGCCGGTCACCACTCCGTGCGGCCACAACTTCTGCGGGTCGTGCCTGAATGAGACGTGGGCAGTCCAGGGCTCGCCATACCTGTGCCCGCAGTGCCGCGCCGTCTACCAGGCGCGACCGCAGCTGCACAAGAACACGGTGCTGTGCAACGTGGTGGAGCAGTTCCTGCAGGCCGACCTGGCCCGGGAGCCACCCGCCGACGTCTGGACGCCGCCCGCCCGCGCCTCTGCACCCAGCCCGAATGCCCAGGTGGCCTGCGACCACTGCCTGAAGGAGGCCGCCGTGAAGACGTGCTTGGTGTGCATGGCCTCCTTCTGTCAGGAGCACCTGCAGCCGCACTTCGACAGCCCCGCCTTCCAGGACCACCCGCTGCAGCCGCCCGTTCGCGACCTGTTGCGCCGCAAATGTTCCCAGCACAATCGGCTGCGGGAATTTTTCTGCCCCGAGCACAGCGAGTGCATCTGCCACATCTGCCTGGTGGAGCATAAGACCTGCTCTCCCGCGTCCCTGAGCCAGGCCAGCGCCGACCTGGAG
Seq A exon
GTAGGGAACGGCCTGCTGGGTGCAGAGGGCAGCCTGGCCTGATGGGTGGTGCAGAGGGGCCACCGGGGGCCTCTCTGCCACACTCTGGACGCCCTGGGGAGATGGGCCTGAATTCGAGGCCGGGGCATCTCCAATGTCAGAGTAGAAAGGGGATGGGAGATTATATAGTCCCTTCCCATCATCCATGAAGACAGGTTAGGTTGCTTGCCATAATCCTGTCATTGTCTGATGGTGTTTATTTTTATTTTTTTGAGACAGGGTCTCGTCCCTCTCACCCAAGCTGGAGTGCAGTGGCGGAATCACAGCTCACTGCAGCCTCGACTTCCCGGGCTTAAGGGATCCTCCTACCTCAGCCTCAAGAGTAGCTGGGACCACAGCCTCCCAAGTAGCTGGGACCACAGGCTCGCTAATTTTTTGTAGAGATGAGGTTTCGCCATGTTGCCCAGGCTGGTCTCGAATTCCTGAGCTCAAGCGATCTGCCCACCTCGACCTCCTAAAGTGCTAGGAGGTCTTTAAAGGCGTGCACCACTGCGCCCCACCATCTGATGGTGTTTAGTAGAGGGTTTTGAATGTCAACTATGAACGTTGGAGGTTACCTCTGTTCCCTCACGAAGTCCTGGTGGCACCCAGGAGGTGGATATGATTTAGTTTCATTTTACTGTTGAGGATACTGAGGTCCAGAGAAATGAACTTAGCCTGACCTAATGCAGTAAATAGCCACGCAGGCATTGTGACCCGGGTTGGTTCGATTTCATAGTTTGCATTTCTTCCCATGGACCAGCCTCGTATCCAGGTCCGTAGAGTCCGGAGCACCAAACAGTCCAGGAAGCTTGAGGTCATGTAAGCAAAAGCCTTTGGTGGGCCGGAGAGTTCCTGTGATCAGGAAGGGTTGTTATTAGAGGCCTAAGAGGGAGGGTGGGCAGCGTCCCAGTAATCACTGGATCAGAGCCACAGGGAGAGCCAACACTCTTGCACCATAGTGTCCTCCGTCCTGGCCGTGTGACTTTGAGCATGGGGTTTGGCCCCTGGACCTGGGTCCTCACCAGTATAGTGAGGCTGTGGGACTAGGTGGATTCCTAAGGGCCTTTCAGGTCTGCAATGTTTTTAGGTGGTTTGGGGATCATACCTTCCCCTTGTGGCCTCAAAGCAGAGGCTGAAATCAAACCACCTTTTGTTACATCAGCCTAAGATCCAAAGCATGGCCTGATTTCATTTCATTCTCACAGCACCTTCAGGGAGAACAAGACCCGTCTTCGTGTTGTCAGAGGAGACAGTAGCCTGAGCAAGGTCAGAGTTGGGGGTCTGCATCCAGCTTTGTGTAGCATATAAACTTGGCTTTTTTTTTCTTTTCTTTTAGAGACAGGGTCTTGCTATGTTGCCTAGGATGTTCTTGAACTTCCGGCCTCAAGGGATCCTCCCATCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGTGCCACCGTGCCTGGCTCTAAACTTGGCTTTTTTTTTTCTTCTTTTAGAGACAGGATCTTACTCTGTCACCCAGGCTGGAGTACAGTGGGGTGATCATAGCTCACTGTAATCTCAAACTCCTGGGCTCAGGTGATCCACTTGCCTCAGCCTCCTGAGTAGGTAGTACTACAAATGTGAGCCACCACACCTGGCTAAGTTTTAAAAAATTCTTTTGTAAAGATGGGATCTCACTATGTTGCTCAGGCTGGTCTTGAACTCCTGGCCTCAATCCTTCTCCCATCTTAGCCTCCTGAGTAGCTGGAACTACAGGTGTGCTACCATGGGGCCTGGCTATAAAATCAGAATTTTTTTTTTTTTTTGAGTTGGAGTCTTGTTCTGTCGCCAGGCTGGAGTGCAGTGGTGCGGTCTCGGCTCACTGCAACCTCCACCTCCCGAGTTCAAGCGATTCTCCTGCCTCAACCTCCCGAGCAGCTGGGACTACAGGCCTGCGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACTGAGTTTCACCATGTTGGCCAGGCTGGTCTCGAATTCCTGCCCTTGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACCACGCCCGGCCCATATATATATATTTTTTAATCTTTTCTTTTAGAGACAGGTTTTCACTCAGTCACCCAGGCTGGACTACAGTAGCATGATCATAGCTCACTATAACCTTAAACCCTGGACTCAGGTGATCCTCCTGCCTCAGCCTCCTGAGTAGCTAGGACTACAAGCACGCACCACCACACCCAGCTAATATTTTAAAACATTTTTTGTAGAGACGGGATCTCACTATGTTGTCCAGGCTGGTCTTGAACTCCCAACCTCAAGGGATCCTCCCACTTCAGCCTCCTGAAGTGCTGGGATTACAGGCGTGAGCCAGGAGCCTGGCCTAAACTCTGCTGTTTAATCCTAACAACAGGCCTTCCTCTGCCAACACCTACCCCCCTGTCCTGACTTGCTGAGTCCTATAACAGGTCTGCTTTTTGAGCCCTGCTACTGCTGCTCATCACTGTTGGCAGAGCCAGTCTCAGCTGGGCAATGCCCTTAGCCTCGGGGGCTGGGTTGCCTTGGCCACTGGTGGGGTCGGACTTGAGACTCTGGTGCCTCCCATGTGGAAGACCCAAGTCTCTAGTCTGTGAAGGGATCCTCAGGATTTCAAAAAGTCCTTTGCCTTTGATTAGGGGATTATTGCTGCTACCAAAGTTTTTGGGTCACTTTCCTTTGGTCTGGAGTCGTGTGGGCACCATTCATGATGAGGGTACTGCCGCATGTGTTTGATTAATGGTGTATCAAATCTTTCAAAATATAGGGCTCAGGGTGTAGTGCTATGAGCAGCTCTTGAAAGTGAAGCAGTTGGCAGCCTTGGGGTGTTCTGAGGTCTCTTCTTGCTCTGAGGCCAGCAAGGCCGGATGTATGTAGGCCTGGTCTTTGGCCCACACCTTATCTTGGCCACTGTTAGAGGCCAGGTCGAAGGGCAGTGTCACAGAGGTCAAGTTTGAAACATCATGAGCAGCTTGGGCTTTTCGGATTGAGTTAGTGTGGCCTTGGTCCCTGCCTCCAACCCCTACATGTGACTGTCACTGGGTTGTTCAAATCTAGATTCAAGATCAGGTTCCGCCCAGAATATCTTGGGTGGAGTTGAAGAGTCTGGGAAGTGGAAGAGAGAGCCAGAGTATGTTGAGCCTGCTAGTTACGGGAAGGAAATTTTTTTTTTCTAGAAATCTCCAGCATGCTCAGTTTGGGCATGTGTCTATGATTTTAATATCGGGATCTTAGCTGTGCCAGTTACTAGTAGTGTAGCTGGGGCAAGTCACTTAATTGTTCTGTGCCTCAGTGTCCTTGTCTGTAAAGGCTGGGTAATTCCTACCTCATAGTGTTGTTCTTAGCTTTAAGTAAGTTAATACAGGTAAAGCACTAGAACAGTGCCTGGCATACAGTAAGTGCATAATAAATACTGGCTGCTGCTGTTATGGTGGTGGTGATTTTCCTTCCCATTTCTGTGCAGTATTCATCTGAGCAGGGAGGTAGGAGACTCAGATATTGATTATGAAAATTAATTGAAATCAGATGAGGATATTAGCTTCCTTCATATACAGTTTGCCTTTGTTTCTGGAGGTGGCTAGGACTGAGCAGATTTGCACCTGGGCTTCAGCCCCTGTGAGCTACTTCATCTTTTTTTTTTTTTTTTTGAGACAGGGTCTCACTTTGTCACCCAGGCTGGAGTGCAGTGATGCCATCTCAGCTCACTGCAGGCTCAACCTCCCGGAATCAAGCGATCCTCCTGCCTCAGCCCCCTAAGTAGCTGGGACTACAGGTGTGCACCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTTGCCATGTTGCCCAAGCTGGTCTCGAACTCCTGAGAGCAAATGATCCACCTGCCTGGGCCTCCTAAAGTGCTAGGATTACAGGCATGAGCCACTGCGCCTGGCTGGCTGATTCATCTTATTCCCAGCCCTTGGTGGTCCCAGTCTGCAGTGAGCCTTGGACTCTGATTTCTGTCTCCCTGCCCTGTGAGGCTGACAAAGGCTCCCAGCCTTGTTCTGGGATTGGCAGATGCCTCTGGAGAGAACATCCTAGATATCAGGCTTATCTCTCTGGGCCCCCTTCCCCCTTCTCCTGGACCTTGACTTCTTAATCCTCTGCTTGATTGGCTCTCCAGCATCTTTTAGCAGATCTCCCCGCTGCCCCATTATTTGGACTGCTTTCCTGGCTGTTTGCAGTGGGAGGATTGGTCTGAGTGGCCCCACCTGCCATTACCGAAGCAGCTGTCCCAGCTCGTTCTGTTCCTGTGTGAGCTTGGCCACCTTTCTGTCCTCCTTGCTTGAGTTTCATTGGCTGTAAAATGGGTAATTAGAGAAAAACTCATAATAATATAAGCTGGCATTTAGTATGTTTTTCCTAAGATCCAGGCATTGGGCTGAGTACTTACATTGTTTCAATTAATCCTCCCAATAGCCCTGTGAGCTGGGGACAGTTGTATCTATTTTGTGTCCAAGAAAACTGAGGTGAAGGACACAGTTGCACAGCTGGGAGTTGGGACTGGAACCCTGGTCTGTACTGTCCTCTGAAAAGGATGAAGGGAAGTAGTAAGTATTAGAATGCTTCAAAAAGCTCCAAGCAGGCAAGACTCGGGTGACAGGACTTGGGGTGGCAAGACTTGGGTGGAGTGGAAGAGGAAGGAATCTATCCTGTGGGATAGTTCCAGGGATGGCTTCTGGTGGGGCTGGGCTGAAGAGGTGCATTCTCAACCTCATTTGTTTTCCCTGCAG
Seq C2 exon
GCCACCCTGAGGCACAAACTAACTGTCATGTACAGTCAGATCAACGGGGCGTCGAGAGCACTGGATGATGTGAGAAACAGGCAGCAGGATGTGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121060-TRIM25:NM_005082:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.075 A=NA C2=0.344
Domain overlap (PFAM):
C1:
PF152271=zf-C3HC4_4=WD(100=20.6),PF0064319=zf-B_box=PU(83.3=22.6),PF0003816=Filament=PU(15.5=10.1),PF033408=Pox_Rif=PU(3.2=2.5)
A:
NA
C2:
PF0064319=zf-B_box=PD(13.0=21.9),PF0003816=Filament=FE(24.0=100),PF033408=Pox_Rif=FE(19.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)