HsaINT0174187 @ hg19
Intron Retention
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:25660]
Coordinates
chr2:166746989-166747498:-
Coord C1 exon
chr2:166747348-166747498
Coord A exon
chr2:166747151-166747347
Coord C2 exon
chr2:166746989-166747150
Length
197 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAAT
5' ss Score
4.94
3' ss Seq
TCTTTTAAACATCTAACAAGGTA
3' ss Score
4.07
Exon sequences
Seq C1 exon
ATAATTATATGACATTATCTCGTTTGATTGATCTCCTAAGAAGATGTGGAAAACTCGAGGATGTCCCAAGATTTTTCTCAATGGCTGAGAAACGTAACTCCAGAGCAAAATTGGAACCAGGATTTCAGTATTGTAAAGGACTGTATCTTTG
Seq A exon
GTAAATCTATTTACAAATAAATGCTACATGATTTTTTTTTCTCATTGTAAATCAAGTAGAATAAGCTTTTCTTTGTAGTAAAAAAAAATGTACATTTCAAAATAATTCAACAGTTTTATTTACCAGACAGATTATAAACTAATATAAATTTTGTAGTCAGTGATTGAAATAAATAATTCTTTTAAACATCTAACAAG
Seq C2 exon
GTACACTGGAGAACCAAATGATGCCCTTCGACATTTTAATAAAGCTCGGAAAGATCGTGACTGGGGCCAAAATGCCCTTTATAATATGATAGAGATCTGTTTGAATCCAGATAATGAAACTGTTGGAGGTGAAGTATTTGAAAACCTGGATGGAGACCTGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607-TTC21B:NM_024753:23
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.287
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCCCAAGATTTTTCTCAATGGC
R:
CCCAGGTCTCCATCCAGGTTT
Band lengths:
252-449
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)