HsaINT0174278 @ hg19
Intron Retention
Gene
ENSG00000018699 | TTC27
Description
tetratricopeptide repeat domain 27 [Source:HGNC Symbol;Acc:25986]
Coordinates
chr2:33036091-33037682:+
Coord C1 exon
chr2:33036091-33036288
Coord A exon
chr2:33036289-33037570
Coord C2 exon
chr2:33037571-33037682
Length
1282 bp
Sequences
Splice sites
5' ss Seq
AAGGCAAGT
5' ss Score
3.24
3' ss Seq
TGTTCTTTCTCCTTCCTCAGGCA
3' ss Score
11.18
Exon sequences
Seq C1 exon
GTCCTTAAAATTCTAGTCAGGGCAGTGATTGATGGGATGACTGATCGAAGTGGAGATGTTGCAACTGGCCTCAAAGGAAAGCTGCAGGAGTTATTTGGCAGAGTGACTTCAAGAGTGACAAATGATGGAGAAATCTGGAGGCTGTATGCCCACGTATATGGAAATGGGCAGAGTGAAAAGCCTGATGAAAATGAAAAG
Seq A exon
GCAAGTCCTTCATTCCTCCTGAGTCCTTGCCTTTCGTTTGAACATGTTGTAGTAGATCTACTTTTTTGATGGGTGGAGGAAGAGTTTAACAATCTGAAAGATAAGATTAGTATGCTTAAGTTCAGTTCTGATTCAGTCTTTAACCTACGTACTTTGAATTGTGGGCTGGTTAAAACTTGTAACATTCATCTTTTTATTTACCATGAAGTTTTCTTACATAGTTGTTCCCTGTTTCCTGCAAAAGGGCCTCTTGAAATGGCCACCCCTACTAAATCTGCAGCAGAGTTGGCTTTTGTTATTTACTCCATACCCCTTTCTGCAGGCACCTTGCTAAAGACTACAGTAGATGGGTACAAGGAGAGAAGGAGTATTTAGATCTGAGATGGGGATTAGGAAAAGAAAAGAGAAAAATGAACAAGATAAAGATCTTGGAAGAGAACTTTTAAGTCAAAACATAATACTTTTACAAAGGTTGCCCTGCCCTTTCTCACAAGTGCGATAGAACACCAGTTCCACTCAAGTTATGCCTTTAGCCTCTTATCTTAGAACTTAAAGGAGCCTGCAGAGTTTCCAAAGTTGGAATAATTGTTTTATGTTTCTTTTCAAAACACCCACAACAAATCAAATGTACTCCTTGCGTGGGTTTGGAATTAGCCACGGCACAGCTAATCTGTGGGATTCTTAGCCATTCTCTCCTCCCTCAATCCACACAGCTGGCTTCCACCGTGGCCTTGTCAGCCCAGAGAACGTGTATCACCTGCACACATGCACACCCTACTTTCATGTCCTTCCATTTCTCCTTGAATTATGGACTTTCTTGCATATATGGAATTAAGAGTACCCAGAATTCTCTGACCTGTGACTTCTCCCTCAAGGATTTGAAAGAGGGTGCATTAAACATCTGTGAGATTACATATATCTACCAGCAGTTTCATTGTTTTAACCAAGTTCATGCCTCATTCTCTAAACAGGTTTTTTAAACTGATGGCTACAAATGCTGAGAAAATCTGTATATTTACAGATTTCCAAACCTGGCCTTTATATCTTTCTGGTTACAGGGAAGTGTCTCAATCCAGGTACATCCATTTGATTTCTTGCCACGGCTTGTTGCCGTTGGGTGTGCATTTCCACCCCTTCTTTGGTGAGAGTAATAGACGCTGTGCTGTACAACACAGATGCTGCTTTTTCACATTGGAATTAGTTCCATATGACTTCCAGGAAACAGAGTTTGAAATGTGAATTCTACTTGTTATTCTGAATGTTGTTCTTTCTCCTTCCTCAG
Seq C2 exon
GCATTCCAGTGCCTCTCAAAGGCATACAAGTGTGACACCCAGTCCAATTGTTGGGAGAAAGATATTACATCATTTAAGGAAGTTGTTCAAAGAGCCTTAGGACTTGCACATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000018699-TTC27:NM_001193509:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.015 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF061226=TraH=PU(28.3=62.1)
A:
NA
C2:
PF061226=TraH=FE(25.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCTTAAAATTCTAGTCAGGGCAGT
R:
CATGTGCAAGTCCTAAGGCTCT
Band lengths:
310-1592
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)