HsaINT0177855 @ hg19
Intron Retention
Gene
ENSG00000113763 | UNC5A
Description
unc-5 homolog A (C. elegans) [Source:HGNC Symbol;Acc:12567]
Coordinates
chr5:176295785-176297535:+
Coord C1 exon
chr5:176295785-176295965
Coord A exon
chr5:176295966-176297370
Coord C2 exon
chr5:176297371-176297535
Length
1405 bp
Sequences
Splice sites
5' ss Seq
ACGGTGGGC
5' ss Score
6.83
3' ss Seq
TCTGCTTGTCTCTCATCTAGTGG
3' ss Score
7.93
Exon sequences
Seq C1 exon
GTGGAGTGGCTCCGGAACGAGGACCTGGTGGACCCGTCCCTGGACCCCAATGTATACATCACGCGGGAGCACAGCCTGGTGGTGCGACAGGCCCGCCTTGCTGACACGGCCAACTACACCTGCGTGGCCAAGAACATCGTGGCACGTCGCCGCAGCGCCTCCGCTGCTGTCATCGTCTACG
Seq A exon
GTGGGCCCCGGGACTCCCTGGTCACAGGGAGAGGCACTGCGGTGCCCCTGGGCAGTGACATGTGGCTGGTGGGGTGAAGAGAGGCCATGAGGCCAAAGCCAGGTGGACCAGATCGTGCCTGACTAGGCAGGATAAGCAAAGGGCTCTCTGTGACTGCTGGGGGCCCAGGGGCATGTCTGGGCAAAGGAGTGGGACAGATTGGAGGTCCTTTGTGGGCAGCGGGCATTGTGCAGAAGGAGATGAGGGACAGGATGGGAATCTAGGAAAGGTGACAGGCTGTCCCCACTCCTGAGTCTCCAAGGGGGGAATCAGAAGCCACACAGTCCAGGCACCCCCAGGAGCCAGCAGAGGGAGGGTGCGGGAGTCACCCCAGGAGAGGCTGGGGTCTGGGCTGCAGGAGTGTGTGAGCCGCGGTTCAGCCTGGCTACCCCGAGTGCCCCCTGGGAGAAGGGAAGACTGTGGCGTGCGTGCTGCAGGGCCCGGGGGCCAGCAGGCACGAGCATGGCCTCCCCCAGGCCTTCTCTCCCAGCTCAGCCACAGCCCACCCGTGTCCAGCTCACAGCCCCTCTGCCCTCACGCCCCGTCCCCTGGGCCAGTGTATCTGAGGACGCCCCCGCTCCCTGACCCCAGTCCTTCTCTGTCCGGCCAGTGAACGGTGGGTGGTCGACGTGGACCGAGTGGTCCGTCTGCAGCGCCAGCTGTGGGCGCGGCTGGCAGAAACGGAGCCGGAGCTGCACCAACCCGGCGCCTCTCAACGGGGGCGCTTTCTGTGAGGGGCAGAATGTCCAGAAAACAGCCTGCGCCACCCTGTGCCCAGGTACCAGCGGCCACCGCCTCCCGCATCGTTCCTCACCACGCCATCTCCGTGCCCTGGCTCCATCGCGCCCACCAGCCTGCCCCCCCATGGCTCCATCCCACCCACCCGCCACGCAGGGCCAGGCTCAGTCTGAGGCGGGGATCGGGGTGCGGTGTATGGTTGGAGTCAGGGCTCGATCTGTGTCCAATGTCAGGGCTCAACATAGGGTGTAAGTCACAGGGTGTGAGGTACAGTTTGACAGGGTCTAGGGCTCAGCCCAGGGCTGCAGAGTCCACTTGTCCCTGGGTTCAGAAGGGTCAACGTGTGACGAGAGAGCCCTCGCTGCCCCAGGGCCAGGACAGCCTCCCTGGTGTGGAGAGAGCCAAGCAGCCCCTGGCGTCATCCGCGCCTCCCTGTCATTAGCATGCGTCATCAAGGCCAGCTGGACACTAGAGGGCGTGCATCGTGGGCCTGGCCCTGGCTTTGCACCCAAATCCAGGCTGCCTTGCACTGCCTGGTCTGGTTGCCCAGAGGGGCCACACTGGCAGACTGCCGGGGTGGGCTCCCAGGCTGACCGCACCGTCTCCTCTCTGCTTGTCTCTCATCTAG
Seq C2 exon
TGGACGGCAGCTGGAGCCCGTGGAGCAAGTGGTCGGCCTGTGGGCTGGACTGCACCCACTGGCGGAGCCGTGAGTGCTCTGACCCAGCACCCCGCAACGGAGGGGAGGAGTGCCAGGGCACTGACCTGGACACCCGCAACTGTACCAGTGACCTCTGTGTACACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000113763-UNC5A:NM_133369:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.016 A=NA C2=0.173
Domain overlap (PFAM):
C1:
PF0767911=I-set=PD(63.7=95.1)
A:
NA
C2:
PF0009014=TSP_1=WD(100=91.1)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGAACGAGGACCTGGTGGA
R:
TGTGTACACAGAGGTCACTGGT
Band lengths:
333-1738
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)