HsaINT0177863 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73053162-73053690:+
Coord C1 exon
chr10:73053162-73053330
Coord A exon
chr10:73053331-73053456
Coord C2 exon
chr10:73053457-73053690
Length
126 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
ACCCTTGCTGTCCCCTACAGGAG
3' ss Score
11.06
Exon sequences
Seq C1 exon
CCCGCTTTCAGAAGGGACCCAGACAGTATTGAGCCCCTCGGTGACCTGTGGACCCACAGGCCTCCTGCTGTGCCGCCCCGTCATCCTCACCATGCCCCACTGTGCCGAAGTCAGTGCCCGTGACTGGATCTTTCAGCTCAAGACCCAGGCCCACCAGGGCCACTGGGAG
Seq A exon
GTGAGGAGCCACGGTGAAGGCTGGCCCAGCTCTCCCAACCTGCCCAGGGAGGCAAAAGAAAGCCCTTTTCCTCTGGCCCAGCCTGAATAACTGTGACCACTACCCCACCCTTGCTGTCCCCTACAG
Seq C2 exon
GAGGTGGTGACCCTGGATGAGGAGACCCTGAACACACCCTGCTACTGCCAGCTGGAGCCCAGGGCCTGTCACATCCTGCTGGACCAGCTGGGCACCTACGTGTTCACGGGCGAGTCCTATTCCCGCTCAGCAGTCAAGCGGCTCCAGCTGGCCGTCTTCGCCCCCGCCCTCTGCACCTCCCTGGAGTACAGCCTCCGGGTCTACTGCCTGGAGGACACGCCTGTAGCACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PD(50.5=91.2),PF094705=Telethonin=PU(14.0=28.1)
A:
NA
C2:
PF094705=Telethonin=FE(67.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCGTGACTGGATCTTTCAGC
R:
GTACTCCAGGGAGGTGCAGAG
Band lengths:
242-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)