HsaINT0178917 @ hg19
Intron Retention
Gene
ENSG00000077254 | USP33
Description
ubiquitin specific peptidase 33 [Source:HGNC Symbol;Acc:20059]
Coordinates
chr1:78187709-78189128:-
Coord C1 exon
chr1:78189016-78189128
Coord A exon
chr1:78187882-78189015
Coord C2 exon
chr1:78187709-78187881
Length
1134 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGT
5' ss Score
9.25
3' ss Seq
AAAACACAAAACAATTTTAGGTG
3' ss Score
3.86
Exon sequences
Seq C1 exon
CTCAGTCTGCATCTCCAAAGAGAAAAAAACAGCACAAGAAATACAGAAGTGTTATTTCAGACATATTTGATGGAACAATCATTAGTTCAGTGCAGTGTCTGACTTGTGACAGG
Seq A exon
GTGAGTATGAGGGTATTAGAATACACAGAAAATTCGTGTCAAATGATTTTTAAAAATGTGACAAGATGATGTGAAAAGTTTAATTCCTTCTCTTTGCTATTGATGAGCATACATGCATTTATTGTGTTTACATCAACACAAATTTGATTCTAGGTGTAGAATTTTTTTTGGAAGTAGCAGCATCCTGTTTAAAGGATGGTGACCCATCATTGGACAGGCACATATTATCCTTCGTCATCTATTTTGGTTACATATAAAGGTGAGAAGTTGCTCAGCAACAAGAATTGGTAACACCTGCATATTCTCCCAGGCTGATGAAATTTGTATACTGGGAATCTGTTGATATTCACAGGTACAAAGCTGTGAATGTATCTCTTACATTTGGTCATATATGGTTTGTAAATATTTTTCCATGTTTAGGATGGGACTCAGATACTAAAGGTAGTATCAAATTCATAGACAATAACAAAGCATACATTAAAATCATCATGAATTTTTTAATAACACTTCTTCAAAGTTTCTTTGAGCTTTTCTTAAGTACAGTTTTACTTTAGTGCAATGATGAATATGAAATAACATCTCAAAAACAAAAAGAAGATTTCAATTATTGTGTTAGAATCTCAAGTCAAATCTAAGAACTTTCAATCGGGTCGTTTTAATGTAGGTTATTTTGGTACTAAATATTTAAGTGGAATTATCAGGCATGTTTTTAGCTATTTAAAATTAGATGCCAGATTTTGTCTCACCCTTTTAAAAAAATATTTTAAAACTACCATCAAAGGTCAATTTTCAAAAATAAATACAATAGTGCTTAAGAGTTTGGACCTCAAGATGCAGTGGCTGGATTTGGGGTGTTTAATGCTGCAGTGTCTGTGATTGTAATGGGGATGCTAATACTACTGCACAGGACTTACGTGAAGATACCTGGTACAGAGCAAGTGTGTTTTGTTTTTTGTTTTTGTTTTTTTTTTTGCTATTATGACTATGAAAGCAGTTCAATTTGCGTGTTTTTTTTTGTTTTTTGTTTTTTTTGCTTATTTAAACATGCTTTGATCTTTAGAGTCTAAAATCTAACCTTGGAAATGTTTTACTGCATTATGTTCATCCCATTTTTAAAACACAAAACAATTTTAG
Seq C2 exon
GTGTCTGTAACCCTCGAGACCTTTCAAGATCTGTCCTTGCCAATTCCTGGCAAGGAAGACCTTGCTAAGCTGCATTCATCAAGTCATCCAACTTCTATAGTCAAAGCAGGATCATGTGGCGAAGCATATGCTCCACAAGGGTGGATAGCTTTTTTCATGGAATATGTGAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000077254-USP33:NM_201624:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.278 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0044324=UCH=FE(13.2=100)
A:
NA
C2:
PF0044324=UCH=FE(10.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCAGTCTGCATCTCCAAAGAG
R:
CACCCTTGTGGAGCATATGCT
Band lengths:
256-1390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)