HsaINT0179937 @ hg19
Intron Retention
Gene
ENSG00000160293 | VAV2
Description
vav 2 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12658]
Coordinates
chr9:136645816-136648713:-
Coord C1 exon
chr9:136648625-136648713
Coord A exon
chr9:136645833-136648624
Coord C2 exon
chr9:136645816-136645832
Length
2792 bp
Sequences
Splice sites
5' ss Seq
TCAGTGAGT
5' ss Score
7.68
3' ss Seq
CTGACCTGCTTCCTTTCCAGCTT
3' ss Score
10.15
Exon sequences
Seq C1 exon
GGGCACCTTCTACCAGGGATACATGTGTACCAAGTGTGGCGTCGGGGCACACAAGGAGTGCCTGGAAGTGATACCTCCCTGCAAGTTCA
Seq A exon
GTGAGTACCCCCCTCACCCCCCCACCCCAGTCCCTGGCCACGCCTGCTCACTTCTGCCCCCTACCACCTGGGTACGGGCCTCGGGCACCATCTCCCACGGGGCAGCGACCAGATGAGGGCACCAGTGCTCACGTGCCCCAGAGCAGACACCAGACGCCTGCCGCACGTCACACACTTAACAGGAGACACAGCCGGGATGAATTCCATTCCAAGCCCTCTCTCCTAATGGGTACTTGAGGACCCCTCCCCATCTCCTGCATCCCCTGCCCCACTCCAGGAGGAAGCTTCTAGAATCTCCACCCCCAAACACGGCACAGAACATTCTCAACAGGTGCATGGAGGTTTCTCATCACAGAAACACCGGTCACCCTGGGTTCTCCCGGCGGGTGAGGCCTGGCCATCAGTAGCTATAGCCATGTTAGTAAATGGTTCAGACACACACACACATGCACGCATACACACATGGCACTTACAGTGGTTCCCTTCTGTTCATGCCCATTTAGGGAAGCTTGAGGCTCAGGGAGGGGAGAGGATTGAGCCAGGCTGGCAGTGGGCAGAGGCAGGGATGCGCCCTGGAGGCTCCTCTGAAGCACCTTGGGTCGGGGGCATACCTTTGGGGTTGTGCCCTGCTCAGGGCAGCTGGACAGCAGTGCAAAGCCTGAGACAGTTCTCTCCTGAGAGGTTTCAGACATCAGGATGTCACCTCCATCATCAGCCCCAGAAACTGAGGCTTGAAACTTTCAGCAATTTGTCTACACTTATTAGCAGAGCTTCTATTCAACAAAGAGCCCCCGGTGGCCCCAGGCCGAGTCTCTGGGTCTTGTCTCCTTGAGCCTCCTGAAGGTGTCTTAAGGCAGAAAAACAAGTCAGGCCAGCTTGTCACCCAGAGATTGTCACCCAGAGACGCCATTGCCCAGAATACATTTTGAGCTGTGATTTTAGATCAATGGTTAATTCACCATTTACTGTGAGTGCCAGCCCAGTACCCTAACCTGGGGAGAGGGCCAGAAGGTCAGCCCAGACCCCCTTGTCCCCATCACAGGCCCAATGCAGCCCCCTAGCTGTGCACAGGATCCCGCAGCCCCTGGAGTTAGTGCTGGAGGATTCCGCAGGCAGCCTGTGGCCTGAACGCAGCTTTTCAGCTGTGCCCATCAATACTGCCCTCTCGTGGTCGCATGTCCCCAGACGATGGCTGCAGCTACTTAGAATCTTTTTTTGCTTTCTCTGATTCTAAAGGTAATGTTTACTTATCAAAAATTTGGAGGAAAAAAAAAGAAATGAAATTTTAAAGAAAGTATCACCCGTGAACTTACCTAGAAATGATGAAAGGCAATGTTTCGGTATATTTCCTTCCAAGTTTTCTTTTTTTGTAATCTTTCTGTTCCTCCCCCGCCCCGCCCCCGCCGGATTATTAATTACTGATTTTCCGTAGAAAATTTGGAAAATGTAGAGAAGTGTAAAGGAGGAGAGAAAAACTACTCCTCCTATCCCCAGGCAAAGCCAGCTGCCACGAGGCCCCAAGCACTGTCCTGCTTTCTGCAGACGCGCACACCCGCCCACCCCATCTCTGTATGGTTTTGAATTTTTCTTAGTATGTGTAGTTGGAACTGCAGGTCTTTTGGAAGCCAGCATTGCTGTCTGCATTCTCCCATGTCCTGGCAGCGCCCTGGCTGGCACCAGCTCCATTCTCCCCAGGGGCCTGTGTCCTTGCCCCCCTCCTCATCCCTCTGCTGGGGGACGCCGTCCTTGCCACTTGTAGCCATTTTTCCCTTAACAGTGTCCAAGCTGCCTTCCCTCTGATCCAGGCTTCTACCTTTGCTCTGGGGTTTGGCTCTGGAAAGTGCTCCTTTGACCATTGTAGCCTTCACCCCTGGGCTCTGCCGAGGCTGGTTTAGCTGTTTGCTGCCCATGGGGGCCGAGATGTCCCGGAGAGATGCTGGCCTCTCCTGAGAGCCTTTCCTGTGGGAAGCCCCCATCAGGCACAGTCATTGCTGCCGTCCAGCTGCCCCCCACCCCTGACCCCTGCCCACTGAGCTGGAACCTGTTCTGTGGTGTCTGTGGATACCTCTGTCTGCCCAGAGCTGTCTGCACTGTGAGTGCTGGGTGGTGTGGAGGTCACGTCAGCGATGTGTGTGAGCTGTTGGGCTCCTTTTCCTCCTTGCCTCCTCTGGTGGTAGGTGGCAGCCACCTTGGCAGATGGCTGGGCCCTAAAGGGCCTTGGGAACATTGGCTCTCCTGGCACCTAAGGTCTTGTGTCCTTGAGCGTGTTGGCACCTGGGTGTCTGAGCTGAGGATGGCAAGCAGGTAGCATGCGTACCAATGCCTCCTCATCACTTGCCCCAGCAGGCATCACTAAGCGGTTGTGGCAGGTAGCATGCATACCAATGCTTCCTCATCACGTGCCCCAGCAGGCATCACTAAGCGATTGTGGAAATCTCCCCTTTGAGTGCCAGGTACCACCCCATGATCCAGGCAGCTGCCGCCATTCAAAAGAGGTGGCCCAGGCGGGATAACCTTTTTGCCAGCTCAGGTCTATTACCCAGTCCAAGTTCTCCCATGGGCCCCCTAAAGCCAGAGCTCAGAATTTGCTGCCAGAAGTAACTGAGAGGCTTTCACAGCCATGAGCTCGGACCTGTGTGTCCATGATCCATGTCCAAAACAGACCACTTTGTAGCTTGGCTCACTTACCATCTTAAGCTCGGCCCAGAGGCTCGGGGCGGTGTGAGTGAGAGCTGCACGGGGCCTTGGCGTCGGTGGCCTCCCCTCTAACACCTGACCTGCTTCCTTTCCAG
Seq C2 exon
CTTCTCCTGCAGATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293-VAV2:NM_003371:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.167
Domain overlap (PFAM):
C1:
PF0013017=C1_1=PD(56.9=93.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)