HsaINT0180187 @ hg19
Intron Retention
Gene
ENSG00000127831 | VIL1
Description
villin 1 [Source:HGNC Symbol;Acc:12690]
Coordinates
chr2:219301847-219303449:+
Coord C1 exon
chr2:219301847-219302035
Coord A exon
chr2:219302036-219303380
Coord C2 exon
chr2:219303381-219303449
Length
1345 bp
Sequences
Splice sites
5' ss Seq
AGTGTGAGT
5' ss Score
6.96
3' ss Seq
GTTATTTACTTTATGTGCAGAAC
3' ss Score
5.74
Exon sequences
Seq C1 exon
GTCTTCTTCTGGATTGGGAAACATGCCAACGAGGAGGAGAAGAAGGCCGCAGCAACCACTGCACAGGAATACCTCAAGACCCATCCCAGCGGGCGTGACCCTGAGACCCCCATCATTGTGGTGAAGCAGGGACACGAGCCCCCCACCTTCACAGGCTGGTTCCTGGCTTGGGATCCCTTCAAGTGGAGT
Seq A exon
GTGAGTGGCCTCATCCCAGCATGTCCTTCTCTAGCCCTGCCTGGAGATCAGTGCTGATTCCTGCAGGCCATTCTGTCTCTTTGGGATATATGACCTGCTGATTTAGAAAGGGGCTAGAGGAGGCTTAGAATAGAAAGTAAGGCTGCACTAAGGCCATTAGGCCTCTGGTGAGAGGGAAGAAGTCTATCAAAAACCAAGGCTAATTATAGTGCCTTGTTTGTGCACTACATTTAGAGCAAAGCTGCTGGATAGTATAGGTAAGAAATGTACTGATTACTTAAATTAAAATTAAACACAGTTCAAAATTCAGTTTGTCACTAGCCACATGTGGCAGCTGGCTACTGTGTTGGGCAGCAGAGGTGAGAATGTTCTCATCATTGCAGCAACATGGTGGATCCTCCATGCCAGCTGAAACACGTTGGTTCTAAAGGACTGACAAATGTCTTCCTGGTGCTAAATTCTAAGCAAAATGGGTCATGTGTGTGGTCCTTACCTGAGGGATGGTGTGCCAACCTCCCACGGGGTGTTTCCTAAACTGGCCCCACATAGAAGCAAGGGGCAGATACCCACAATGGAACTCCAGCAAAGGTTTTCGGTAGGAAGAAGGCCAAGGTACAGTGAAGCCTGGCCTGGTGGCTCTGGGTGCTCTAAATTGTCACAACAGATGGCTTTAGGGAAGCAGAAAGCTTAATTTCCTTAAATTTGTTGGTTTGTTTTTTTAAATTCTGCAGTTAGATGGGCTTTTAGTTTTTACTCAAGGCAGCATATCGAGATGCCAGGTTTTCTCAATCCACTTTAGTTATCACCTTTCCCTCACCTCAAGTGTGTGCTGGCTTCTCTCTCAGCCTCATTCACTCATTCATTCATTCATTCATTCAGCATAAGTGTGCTCTAGGATATGGAGATGGGACTCCTCAGAGCCATGGTCCCTTCACTCCTCTGTGGCAGGGCTCCCTTCTATTATCTGGGGGGACCCCCACCCATCCCCAGGAGCCCTGCATTTCCCAGAGCCTACATAGCCTAGGCAGGGTTCTCCATACTGCCTGTGGGTTCTTGCCCTGGCCCCTGCAGGTGGCAAAAGATCCTGCCCATCCCCATGTCAGGCTGAGCTGGGACAAATATAGCCTGCGCTCCACTTTTCTGATCTGGCAGCCCCTCTGGTCCCAATCTCACCATCTAATCTCCTTTTTCAGGGACCCTCCTCCAGCCTCAGCCTTCATATCCTCTTTCCTTTCTTACCACTAGGCCCCAGACCAGCCTTCTTTTCATTCCTGAGGGAAAATGGCTTCTCATCCATCTCCTCTGCTGAGATCCAGGTCTAATCTGTTATTTACTTTATGTGCAG
Seq C2 exon
AACACCAAATCCTATGAGGACCTGAAGGCGGAGCTTGGCAACTCTAGGGACTGGAGCCAGATCACTGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000127831-VIL1:NM_007127:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.413 A=NA C2=0.043
Domain overlap (PFAM):
C1:
PF0062617=Gelsolin=PD(63.3=79.4)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTTCTGGATTGGGAAACATGCC
R:
AGCAGTGATCTGGCTCCAGTC
Band lengths:
254-1599
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)