HsaINT0186197 @ hg19
Intron Retention
Gene
ENSG00000125846 | ZNF133
Description
zinc finger protein 133 [Source:HGNC Symbol;Acc:12917]
Coordinates
chr20:18286325-18287037:+
Coord C1 exon
chr20:18286325-18286451
Coord A exon
chr20:18286452-18286941
Coord C2 exon
chr20:18286942-18287037
Length
490 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGC
5' ss Score
8.84
3' ss Seq
TTTTCTTTTCCTGTGAGCAGGAA
3' ss Score
8.24
Exon sequences
Seq C1 exon
GCACACATGGCATTCAGGGATGTGGCTGTGGATTTCACCCAGGATGAGTGGAGGCTGCTGAGCCCTGCTCAAAGGACTCTGTACAGAGAGGTGATGCTGGAGAACTACAGCAACCTGGTCTCACTGG
Seq A exon
GTAAGCCTGATATCTGTTAGGATTCCCATTCTTATTGCTGGGAATTTTAGGCTATGCTTGAAGCAGCCATCTTGCTTTGTTACTTGACCTTTGGGTTGGACCAAAAAGCAACTACATTTTATTCGTGTTTCCCCAGGGAGGGTCTGATTTTGCAGAGTGGAAAATGGGTAGATTTGTTGTGTGTGTGCATATGTGTATTGTGTGTGCTACTCTGCATTTCTAGGCCTTTTTTCTCAGGCTGGGGTTCTCATCCTATGTTAACTTGTTTTAAATGAGAGGGGTGTTCATCTACTCGGCATGGAATAGAATCAGTGTACTCTCATCTGAGTTCACTGCCCACTCATCCCTTCCATTTCTGAGAGCCCCACTCACCTCTTCCAACTCAGGGCTTTGTACTACCTTTGAAGTTTCCTAGGCTGTTTAGCTTTGAATTCTTGAATGGGCTCTTGAGCCCATAACCTAGTTACTTATTTTCTTTTCCTGTGAGCAG
Seq C2 exon
GAATTTCATTTTCTAAACCAGAACTCATCACCCAGCTGGAGCAAGGGAAAGAGACCTGGAGAGAGGAAAAAAAATGTTCACCGGCAACCTGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125846-ZNF133:NM_003434:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.424
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=100.0)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCACACATGGCATTCAGGGAT
R:
CTGGACAGGTTGCCGGTGAA
Band lengths:
223-713
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)