HsaEX0073029 @ hg19
Exon Skipping
Gene
ENSG00000125846 | ZNF133
Description
zinc finger protein 133 [Source:HGNC Symbol;Acc:12917]
Coordinates
chr20:18269121-18297640:+
Coord C1 exon
chr20:18269121-18269248
Coord A exon
chr20:18286325-18286451
Coord C2 exon
chr20:18295713-18297640
Length
127 bp
Sequences
Splice sites
3' ss Seq
GGCTCAGTTTTGTGTTACAGGCA
3' ss Score
6.78
5' ss Seq
TGGGTAAGC
5' ss Score
8.84
Exon sequences
Seq C1 exon
CGCCGAGCATCCTGGGAGGTGTGGTCCGGGCGCTGTGCCGAGGATTCGGGGTAGTGTAGTCCTGGCGCCCCGCTGGAGGAGCTCCCCAGCTGGTGGCTGGAGCGACCCCTTGTTCTTTGGTGGCGCTG
Seq A exon
GCACACATGGCATTCAGGGATGTGGCTGTGGATTTCACCCAGGATGAGTGGAGGCTGCTGAGCCCTGCTCAAAGGACTCTGTACAGAGAGGTGATGCTGGAGAACTACAGCAACCTGGTCTCACTGG
Seq C2 exon
CAGATCCAGAGCCAGAGCTCTACCTCGATCCTTTCTGCCCTCCGGGTTTCTCCAGTCAGAAATTCCCCATGCAGCATGTGCTGTGTAATCATCCCCCCTGGATCTTCACATGCTTGTGTGCAGAAGGTAACATCCAGCCTGGGGATCCGGGCCCAGGGGACCAGGAGAAGCAGCAACAAGCCTCTGAGGGGAGACCCTGGAGTGATCAAGCAGAAGGTCCTGAGGGAGAAGGTGCCATGCCTTTGTTTGGAAGAACCAAGAAAAGGACTCTGGGAGCGTTCTCCAGGCCACCCCAGAGGCAGCCAGTCAGCTCTCGGAACGGCCTCAGAGGGGTGGAGTTAGAAGCCAGCCCAGCTCAGTCAGGGAACCCTGAGGAAACAGACAAATTGTTGAAGAGGATAGAAGTCTTAGGATTTGGAACAGTCAACTGTGGAGAGTGTGGACTGAGCTTCAGCAAGATGACAAACCTGCTCAGTCACCAGCGGATACACTCAGGGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125846_MULTIEX1-5/8=C1-C2
Average complexity
C3*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.279
Domain overlap (PFAM):
C1:
NA
A:
PF0135222=KRAB=WD(100=100.0)
C2:
PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.3),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.1),PF0009621=zf-C2H2=WD(100=3.9),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.5),PF134651=zf-H2C2_2=WD(100=4.5)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGACCCCTTGTTCTTTGGTGG
R:
TTCTCCCTCAGGACCTTCTGC
Band lengths:
256-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)