HsaINT0186507 @ hg19
Intron Retention
Gene
ENSG00000131115 | ZNF227
Description
zinc finger protein 227 [Source:HGNC Symbol;Acc:13020]
Coordinates
chr19:44732599-44733969:+
Coord C1 exon
chr19:44732599-44732725
Coord A exon
chr19:44732726-44733885
Coord C2 exon
chr19:44733886-44733969
Length
1160 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
AAAAATCTACATTTTCATAGGGC
3' ss Score
5.13
Exon sequences
Seq C1 exon
GAGGCTGTGACATTCAAGGATGTGGCTGTGGTCTTCTCCAGGGAGGAACTGCGACTGCTCGATCTTACCCAGAGGAAGCTGTACCGAGATGTCATGGTGGAGAACTTCAAGAACCTGGTTGCAGTGG
Seq A exon
GTGAGGACAGGCACTCTCTGACCCTGAACTTCAGTTCCCTTGAGAATCTCTTTGCTCTCAGGTGTTTAAGGGTTTGGACCTTTTAAAATGGTTCTTTGCTCTTGAAGACAAAAGGTTTTCTAATCCCTGGGAAAACAGGATAGGTTTTTCTGGTCTTTCTGCTCAGGCAAAATTCTGTCCTTTTAAATTGCTGGTTCTCAACCATGGGTGATTTCGCCCCCAGAAGATATTTGGCAATGTCTGGAAATGGTTGTCACACCTGACAGAGGGGTGCTATTGGCATTTTGTGGGTAGTATCCAGGAATTCTGCAAAATCTCCTACAGTGCACAGGACAGTGCCCCCAACAGAGAATTGGCCAGTCCAAAATAGTAGTGCTGCAGTTGCAAAACCCTGTTTTAAATGAACCGTAAATGGACACATTAGCTTCTATGCTTTATCTTTCAAATACGTTGTCTTTCAAATGAAACCCATCAATGCATTAACTTAGTGCACTGTACTGGCTTTTTTTTCAATGAAATAAAACAGATAAGGATAGAAAATATCAGAGCTTCTTATCAGGAACTGCTCACATTGCAACAAAAACTGACAATTTTCAGTGAATGGTGTGAGATACAGCATTGCAAATGTGATGAAAACAGACATTAGCCAAGTATAACTTGAGAGAGAGATATATTATATATATATGAACTAGGCTACAACCTAAATTTCTTATTATAGTTCATGATCTTAAAACATCTTAAAATAAATCACTCTAGAGGCCGGGCATGGTGGCTTACGCCTTTAATTGCAGCAATACGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCACGAGTTCAAGACCATCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATGCAAAAATTAGCCGGGTGTGGTGGCAGGTGCCTGTAATCCCAACTACTCGGGAGGCTGAGGCAGGAGACTTGCTTGAACCCTGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCATTGCACTTCAGCCTGGGCGATAGAGTGAGACTCTGTCTCAAAATAAATAAATAAAATAATAAAATATCACTATAGAGGTTGTGAGGCTTATAGGGTTCAGACAAAAATGTGTTTTAGTTGTGTGTTCATCTTAAATACATAAAAATCTACATTTTCATAG
Seq C2 exon
GGCATCTTCCCTTCCAACCAGATATGGTATCCCAATTGGAAGCAGAAGAAAAGCTTTGGATGATGGAAACAGAAACCCAAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131115-ZNF227:NM_182490:4
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.172
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGCTGTGACATTCAAGGATGT
R:
TGGGTTTCTGTTTCCATCATCCA
Band lengths:
206-1366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)