HsaINT0186507 @ hg38
Intron Retention
Gene
ENSG00000131115 | ZNF227
Description
zinc finger protein 227 [Source:HGNC Symbol;Acc:HGNC:13020]
Coordinates
chr19:44228446-44229816:+
Coord C1 exon
chr19:44228446-44228572
Coord A exon
chr19:44228573-44229732
Coord C2 exon
chr19:44229733-44229816
Length
1160 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGG
5' ss Score
6.74
3' ss Seq
AAAAATCTACATTTTCATAGGGC
3' ss Score
5.13
Exon sequences
Seq C1 exon
GAGGCTGTGACATTCAAGGATGTGGCTGTGGTCTTCTCCAGGGAGGAACTGCGACTGCTCGATCTTACCCAGAGGAAGCTGTACCGAGATGTCATGGTGGAGAACTTCAAGAACCTGGTTGCAGTGG
Seq A exon
GTGAGGACAGGCACTCTCTGACCCTGAACTTCAGTTCCCTTGAGAATCTCTTTGCTCTCAGGTGTTTAAGGGTTTGGACCTTTTAAAATGGTTCTTTGCTCTTGAAGACAAAAGGTTTTCTAATCCCTGGGAAAACAGGATAGGTTTTTCTGGTCTTTCTGCTCAGGCAAAATTCTGTCCTTTTAAATTGCTGGTTCTCAACCATGGGTGATTTCGCCCCCAGAAGATATTTGGCAATGTCTGGAAATGGTTGTCACACCTGACAGAGGGGTGCTATTGGCATTTTGTGGGTAGTATCCAGGAATTCTGCAAAATCTCCTACAGTGCACAGGACAGTGCCCCCAACAGAGAATTGGCCAGTCCAAAATAGTAGTGCTGCAGTTGCAAAACCCTGTTTTAAATGAACCGTAAATGGACACATTAGCTTCTATGCTTTATCTTTCAAATACGTTGTCTTTCAAATGAAACCCATCAATGCATTAACTTAGTGCACTGTACTGGCTTTTTTTTCAATGAAATAAAACAGATAAGGATAGAAAATATCAGAGCTTCTTATCAGGAACTGCTCACATTGCAACAAAAACTGACAATTTTCAGTGAATGGTGTGAGATACAGCATTGCAAATGTGATGAAAACAGACATTAGCCAAGTATAACTTGAGAGAGAGATATATTATATATATATGAACTAGGCTACAACCTAAATTTCTTATTATAGTTCATGATCTTAAAACATCTTAAAATAAATCACTCTAGAGGCCGGGCATGGTGGCTTACGCCTTTAATTGCAGCAATACGGGAGGCCAGGGTGGGTGGATCACTTGAGGTCACGAGTTCAAGACCATCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATGCAAAAATTAGCCGGGTGTGGTGGCAGGTGCCTGTAATCCCAACTACTCGGGAGGCTGAGGCAGGAGACTTGCTTGAACCCTGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCATTGCACTTCAGCCTGGGCGATAGAGTGAGACTCTGTCTCAAAATAAATAAATAAAATAATAAAATATCACTATAGAGGTTGTGAGGCTTATAGGGTTCAGACAAAAATGTGTTTTAGTTGTGTGTTCATCTTAAATACATAAAAATCTACATTTTCATAG
Seq C2 exon
GGCATCTTCCCTTCCAACCAGATATGGTATCCCAATTGGAAGCAGAAGAAAAGCTTTGGATGATGGAAACAGAAACCCAAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131115:ENST00000313040:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.363
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGCTGTGACATTCAAGGATGT
R:
TGGGTTTCTGTTTCCATCATCCA
Band lengths:
206-1366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains