HsaINT0187319 @ hg38
Intron Retention
Gene
ENSG00000178187 | ZNF454
Description
zinc finger protein 454 [Source:HGNC Symbol;Acc:HGNC:21200]
Coordinates
chr5:178946359-178946986:+
Coord C1 exon
chr5:178946359-178946485
Coord A exon
chr5:178946486-178946896
Coord C2 exon
chr5:178946897-178946986
Length
411 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
3' ss Seq
TTGTCTCCCCTTAAAAACAGGAC
3' ss Score
7.91
Exon sequences
Seq C1 exon
GAATCGGTGACCTTCAAGGATGTGGCTATACTGTTCACCCAGGAAGAGTGGGGGCAGCTGAGCCCCGCCCAGAGGGCCCTGTACAGGGACGTGATGCTGGAGAACTACAGCAACCTGGTCTCACTGG
Seq A exon
GTAAGTGGGACCCCTGCAAGGTTTCTCTTCACTTTTGGGGATCTCTTTGGGACCCTTACATTGACACCATATAGAAGAGTCGGTTGGACCAACTGAGGACGCTGTCTTCAAGGGTGCCATTAATTTTACCTGTCCTTGGTGTCCTGGGCACAGGCCTCTTTTGGAGTCCACTGCGGATGCCTCAAAAGTGACTAGGGTCAAATGCTTTCTTTCTGGCAAGGAGGGGAACATGGGATAAGATTGTGTCAGGCCTGAGTAATCTTTTCCTCCCTCTGGGAACACACCTGACCCTGGGCTTTCCTATCAAGTCCCATTTCCCAGCAAGCTCTGAGGACCAGGCTTTGTCTTTGCAGTGATTTTTATCTCTCGTATAAACAGATGTGGTTCATTTTTGTCTCCCCTTAAAAACAG
Seq C2 exon
GACTCTTAGGACCCAAACCAGATACGTTTTCCCAGCTAGAAAAAAGGGAAGTGTGGATGCCAGAGGACACCCCTGGAGGCTTCTGTCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000178187:ENST00000320129:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.151
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=95.3)
A:
NA
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGGTGACCTTCAAGGATGTG
R:
CAAGACAGAAGCCTCCAGGGG
Band lengths:
214-625
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains