HsaINT1002764 @ hg38
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]
Coordinates
chr9:133443376-133445052:+
Coord C1 exon
chr9:133443376-133443561
Coord A exon
chr9:133443562-133444862
Coord C2 exon
chr9:133444863-133445052
Length
1301 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
3' ss Seq
CTGTCTCATGCCATCCTCAGGTG
3' ss Score
9.58
Exon sequences
Seq C1 exon
CTGGGCGGTGGGAGACTTCGGCCCATGCAGCGCCTCCTGTGGGGGTGGCCTGCGGGAGCGGCCAGTGCGCTGCGTGGAGGCCCAGGGCAGCCTCCTGAAGACATTGCCCCCAGCCCGGTGCAGAGCAGGGGCCCAGCAGCCAGCTGTGGCGCTGGAAACCTGCAACCCCCAGCCCTGCCCTGCCAG
Seq A exon
GTGAGCCCAGGGCTAGGTGGGGCTGGGAGAGGGCCTTCCTGGCAGAGCTCGTCCCTGCGCTGAGCCCCCATCCTTCTGAGAATCCCCTCCTCCTGAGGCCTCCGGCGGGGCCTCACCATCCAGGGTGATGGGCAGTGTCACCTGGCGGTTGTAAGTGCTGCTGTCAGAGTTCCTTACTACCCAGGAGAGCCTGGGCCCATTGTTTCCCTCTCTGAGCTTCCGAGCCCCTGCTCTGAAATGGGGATGCCGACCTGCCTGGGGAGGGGGGGCTTCGAGGATGAGGTCAAACTGAACGGAGTGGGAGATGTCACTTTCTCATCACCACCATCTCCCCCGTGCCCACGTGGCTGCATCTCATCCCCTCAGTGTCCAAGTTGACAGTGGCTTATCATCCTGCCCTGCCACTAACGAGCTGAGTGACAGGGCAAGTCCCCTCCTCTGTGGGCTTCAGTTTTGCGACCTGTCCGGTGGGAGGGGATTGGTCTGGATTGTTGGTGGCCCACTCATAGCTCTGGACTCCTTTCCCCGCCTCGTCATCCGTGGCAGACAAAACAGTCACCACTCTTCCCCGCTGAGGCCAGATAGGGCCTCAGAATCCTTCTCACACAGCTCTCCAGGCAGCCACTTTAGCGCAGGGCTGACTCACAGCTGAAACCCATTGGCCACCCTTGAACCTGGTGATCCAATTCCATGTGGCACCTGTTTCTCTGCACCTGCTATGGTGCATGGAGTCAGTGATTACCTGGCTGGAGGTCGGCCTCTGCCTCTGGAGAGTAGGAGGGATGGGTTCTCTTTTTTTTTTTTATTAAAAGACAGAGTCTTGTTCTCTCACCCAGGCTGGTATGCAGTGGCATGATCTTGGCTCACTGCAACCTCCTGCCTCAGCAAGTGTGCGCCACCAAGCCCAACTAATTTTTGTATTTTTTGTAGAAACAGGGTTTTGCCATGTTGCCCAGGCTGGTCTCCAACTCCCGGGCTCAAGCAGTCTGCTCACCTCAGCCTCCTAAAGTGCTGAGCTACCGTGCCTGGCCAGGGATAGGTTCTGTCTCTGCACCCTGGGTGCAGGTGGGGTGCCTGACTGTTGAGCAGCGAGTGCTTGTTGAATGGGAACCTGCTGGCTGATGAATGGGGAACCCGGTGCTTCAGGGAGAGACCCTGAGCTTCACTTCTCTGTGGGGCTCCTCTTTGGGCTCCTGGATGTTGGGGAGCAGGTCCCCTTCCTCCCTGCCCCTAGCAGCTGGGCTATACCTTCCCCTGGGTGGCAGAGGCAGGGCCTGATGACTGTCTCATGCCATCCTCAG
Seq C2 exon
GTGGGAGGTGTCAGAGCCCAGCTCATGCACATCAGCTGGTGGAGCAGGCCTGGCCTTGGAGAACGAGACCTGTGTGCCAGGGGCAGATGGCCTGGAGGCTCCAGTGACTGAGGGGCCTGGCTCCGTAGATGAGAAGCTGCCTGCCCCTGAGCCCTGTGTCGGGATGTCATGTCCTCCAGGCTGGGGCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323:ENST00000371929:19
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.250
Domain overlap (PFAM):
C1:
PF0009014=TSP_1=WD(100=92.1)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGACTTCGGCCCATGCAG
R:
AGGACATGACATCCCGACACA
Band lengths:
350-1651
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains