HsaINT1010478 @ hg38
Intron Retention
Gene
ENSG00000138115 | CYP2C8
Description
cytochrome P450 family 2 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:2622]
Coordinates
chr10:95067529-95069497:-
Coord C1 exon
chr10:95069235-95069497
Coord A exon
chr10:95067692-95069234
Coord C2 exon
chr10:95067529-95067691
Length
1543 bp
Sequences
Splice sites
5' ss Seq
AATGTAAGT
5' ss Score
8.62
3' ss Seq
ATTTGCATTTCCTTTCCCAGTTC
3' ss Score
9.18
Exon sequences
Seq C1 exon
ACATGTCAAAGAGACACACACTAAATTAGCAGGGAGTGTTATAAAAACTTTGGAGTGCAAGCTCACAGCTGTCTTAATAAGAAGAGAAGGCTTCAATGGAACCTTTTGTGGTCCTGGTGCTGTGTCTCTCTTTTATGCTTCTCTTTTCACTCTGGAGACAGAGCTGTAGGAGAAGGAAGCTCCCTCCTGGCCCCACTCCTCTTCCTATTATTGGAAATATGCTACAGATAGATGTTAAGGACATCTGCAAATCTTTCACCAAT
Seq A exon
GTAAGTCTGCCTTATGTTCCTCCAGCCAATTGCAAAGGGTAAGTTATTTGACTGCTATTTTTAGACAAAATATATTCCTGGAAGCACACTATTATAATAGATCATTGTAAAGCAAAATACTCCCTCTGAACTTCTTTGATGTTTCTTTTGTCTTCCTATTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTATTGCCCAGGCTGGAGTGCAGTGGCACTATCTCCACTCACTGCAAGCTCTGCCTCCCAGGTTCACACCATTCTCCTGCCTCAGCCTCCCCCGAGTAACTGGGACTACAGGTGCCCTCCACCATGCCCGGCTAATTTTTTGTATGTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGAATGGTCTCAGTCTCCTGACCTCATGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACATGTGTGAGCCACCGTACCTGGCCTCTTTTGTCTTTCTAAGTCTGTCATTGTCAGAAATAGCGGAGTGAGTTGATGCATTTTGTGAATACAGAAACATTGGGGTCATTGTATTATATAATCATTTAATACAGTGGCAAAAGTTTAAAGTGCTGTTTCTCCTCTTTGTTTCACAGTGTTTTGCTATGATTTTTGACTGAAGGTGAAGGGAAGTGTGTGTGATTAGAAATTTCATCCAATAAGTTCTCTACTATAGTAGTCATGTGTTTTATTCAGAATGGTCATGAAAATTGAACTTCTCTGAAGATTCATTTGATGGCTGATGTGAAATAAATATCTGTGGGTTCAGGGCAAACATAAGTGCATGAAAGAAAGAAGTAATCAGTCAGGGCCCAATAGGTAGTTAACAGAATTCTTTTGGATTCTGAAGAAAGCCACTGTCTGTGGCCAAGGTTGCTGGAGAATGGAAGAAATTGTTCTTCCAGGAGATGCTGAATGTCCTGATTCTAACTTTGTGGTGCTTCATCGTTCCATATTGGTAATACCAGCAGTTACAAACTGGACTGGGCATTAGAATCACCTGGGGTGACACTGTAAATACAGATTTCTAGGGTTCATCACAGGACTGCTGTATCAGAATCCTCATGTTAAGAGCTTTACAAGTGACCCTGAAGTCTTTAGCTGGGTAGTGGCCTCAAGGTGGACATGGGGGATTGATTAATTGCTCAAGCATCAGTTTAAATTAGCAGAGATTCCAGTTTGGAGCTTCTACATATTACCTGTGGGACTCTGAGAATGAATCTGCAATTCTCTGGCCTCAGTTTCTTCATTTTTAAAACAGGTCAAATGAATGTGCTGAATGTGTTGAAGTGAGGATGAACTGTGTGATTTGTGTACCAATTGCCTGGGTCATTGCGTGGCACATCACAGGCCATCTATAAGTGGCAGCTATAACAATCACCATCACATTTATGTACAAAATTCAGAAATATCGAATCTATGTGTGGCAAATATGAACATTAAAAAATACAATGAAAATGTCAGTCTGAATCATACATAGTATTTGGAGCAAATAGCGACTTATTTTGCTGCTATTTGCATTTCCTTTCCCAG
Seq C2 exon
TTCTCAAAAGTCTATGGTCCTGTGTTCACCGTGTATTTTGGCATGAATCCCATAGTGGTGTTTCATGGATATGAGGCAGTGAAGGAAGCCCTGATTGATAATGGAGAGGAGTTTTCTGGAAGAGGCAATTCCCCAATATCTCAAAGAATTACTAAAGGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138115:ENST00000371270:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0006717=p450=PU(5.7=46.4)
A:
NA
C2:
PF0006717=p450=PD(23.1=75.0)
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTGGAGTGCAAGCTCACA
R:
TGGGGAATTGCCTCTTCCAGA
Band lengths:
352-1895
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains