HsaINT1011203 @ hg38
Intron Retention
Gene
ENSG00000144355 | DLX1
Description
distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2914]
Coordinates
chr2:172085226-172086853:+
Coord C1 exon
chr2:172085226-172085990
Coord A exon
chr2:172085991-172086653
Coord C2 exon
chr2:172086654-172086853
Length
663 bp
Sequences
Splice sites
5' ss Seq
CAGGTACGT
5' ss Score
10.65
3' ss Seq
TACTTCTGCTGTCCCTCCAGGGG
3' ss Score
9.67
Exon sequences
Seq C1 exon
GGGAGGCCGATGAGCCGCGGGCCGCAGGGGCCCCGGCGCAGACGCCGCAGCCCATTGTGCTTCCTGCCCGGCGCGCTCTGTTGCAGAGGAGCCCCGGCCGGGAAGTGTGGATGCGTCTTACCCGAGGCCGGGCCGCCTCGCCCGCTCTAGTCCAGCGGAGCCCGAGCGCCTCGGACCAATCCCCAGTGATTATGCAAGACAGCGGACCAATCAGCTCCGCCAGCTCATGAATATTTATGACCTTCGCTGAGTCAAAGCTTTGAACCGAGTTTGGGGAGCTCAGCAGCATCATGCTTAGACTTTTCAAAGAGACAAACTCCATTTTCTTATGAATGGAAAGTGAAAACCCCTGTTCCGCTTAAATTGGGTTCCTTCCTGTCCTGAGAAACATAGAGACCCCCAAAAGGGAAGCAGAGGAGAGAAAGTCCCACACCCAGACCCCGCGAGAAGAGATGACCATGACCACCATGCCAGAAAGTCTCAACAGCCCCGTGTCGGGCAAGGCGGTGTTTATGGAGTTTGGGCCGCCCAACCAGCAAATGTCTCCTTCTCCCATGTCCCACGGGCACTACTCCATGCACTGTTTACACTCGGCGGGCCATTCGCAGCCCGACGGCGCCTACAGCTCAGCCTCGTCCTTCTCCCGACCGCTGGGCTACCCCTACGTCAACTCGGTCAGCAGCCACGCATCCAGCCCCTACATCAGTTCGGTGCAGTCCTACCCGGGCAGCGCCAGCCTCGCCCAGAGCCGCCTGGAGGACCCAG
Seq A exon
GTACGTGCGCTTGCCAGGGAGAGGGAGAGGAGGAGGTACAAGGGAGAGAGGGAAAGAAGGAGCGGGGGAGAAGAGGAGAGGGAGAGAGAGAGAAAGAGAAGAGAGGAGAGCGAGGTGGGGTGGGGGTGGGGAGGGCGCGGGAGCAGTGGAGGTTTCGAATATCAATCTATAGATCCTTGTCACAGCAAATAAATTTTTTTAAAAATTCCCTCAATTTGCAACTATCCAGCCAAGGATAAATCCCAGAGCGTCTCCTGGCACTGGCTGGGCCTCTGGGCGGCTCGGTGTGCAGAGCACACAATGCCCCGCTGGAAAACAGAAACCCACATGTGCACGTATTAGTCTCGGTAATTATTTATTGCGTAGCGCTATAAACAATGTATGCAATTAAGGGTAATTAAACCTCAACTACCGCCTGCAAAAATAGCAAACTTTCCCTGCAAAGGCAGGAGCTGAGCTCCTGGGAACGGCTCTATCCCTCCTGCAGCGTCCCGGGACAGGCCCTCGGATTTTGGGGGACCCTTCCCTGGCTTTCAGAGTTTCTTGAACGTTCTCTCCCTGGTGCTGCCTCCGCCACCCTTCGGTAGCCACTCGCTCTCGGCTGTTCGCACTAAAGGCGGCCCCTCGTATTAACAACGGGCCCTACTTCTGCTGTCCCTCCAG
Seq C2 exon
GGGCGGACTCGGAGAAGAGCACGGTGGTGGAAGGCGGTGAAGTGCGCTTCAATGGCAAGGGAAAAAAGATCCGTAAACCCAGGACGATTTATTCCAGTTTGCAGTTGCAGGCTTTGAACCGGAGGTTCCAGCAAACTCAGTACCTAGCTCTGCCGGAGAGGGCGGAGCTCGCGGCCTCTTTGGGACTCACACAGACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144355:ENST00000361725:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.612 A=NA C2=0.351
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0004624=Homeobox=PU(73.7=62.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCACTACTCCATGCACTGTT
R:
CGGCAGAGCTAGGTACTGAGT
Band lengths:
356-1019
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains