HsaINT1011308 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123871457-123873710:+
Coord C1 exon
chr12:123871457-123871602
Coord A exon
chr12:123871603-123873557
Coord C2 exon
chr12:123873558-123873710
Length
1955 bp
Sequences
Splice sites
5' ss Seq
AACGTAAGT
5' ss Score
10.74
3' ss Seq
ATCATCTCTTTCTGCTTCAGATT
3' ss Score
10.84
Exon sequences
Seq C1 exon
TTCACACAGTGGATACCACTCGGACTACCTGGATATTGGAACAAATGGTTAAAATTAAGCAACCTGTTATTTTTGTTGGTGAATCTGGCACTTCTAAGACAGCCACTACCCAGAATTTCCTCAAAAATCTGAGTGAAGAAACTAAC
Seq A exon
GTAAGTCATTATTCATATGAATTATCTATTGCTGTGTAACAAATTATTCCAGTGCATAGCAGCTTCATACCACAAGCACTGTGATCTCACAGTTTCCGTGGGTCGAGAATGTGGGAGTGACTTACCTGGGAGCTTCTAGCTCAGGCTCTCATGGGATTGCAGTCAAGCTGTTGGCCAGGGCTGTAGATACCTGGAGGCCTGGGTAGAGCTGGAGGATCCTCATTTGAGATGACGTTTCACATGGCTGGAGGCTGGAGGCCTCAGTTCCTCACCATGTGGCTCTCTCCATGGATGGCTTGGGTGTGCTCAACATGGTAGAGTGAGTGCTTAAGATAGATGGCAAAGCAGATGCTATGATGTCTTTTATGACCTGGCCTTGGAAGTCACATACCCTCCCTTCTGCCCTAATCTATGGGTGAGATAGAAGCCACCCTGTACACCCTGATATAGTGTGGGAGGGACCTGCACCAGGGCATGGACACCTGGAGGTGAGTATGATCTGGGGCCCTTTTGGAGGCTGGCTGTCACATTATTCACCATCATTTTTGGGTTTCTAAAACTTTGCAAGTGTTTCCTTTCCTTCCTCCAGCCAGCTATGTGTCCAATGTGTCGGGGGTCGGATATGTACCTGGCATAGAATTCGCAGGGTGCACAGGACAAGTGATAGTGAACAAGCTGTCAAGATCTGTTCTGTAGGGATTTGCAGGCAGTGGGGGGATAAACATGGAGATGTGCACAGGGAGCATGGCAGTGTTTACAGCCAGAGGGACCTGCAGGTTTGTGGAGTCAGGCACTAGGAAGCCGCATTTGGGAGCCTCCTTCACAACACCCCTACCCCAGGACTCTGCAGCTGGTGCTCATCAGCCCAGCCAGGTACACCTGAACACAGTGGCTTTAGCAAGGTACACATTCAGCTTCAACACGTTCAGCTCATGTGCACCTGCACTTTGGGTGCCCTACGTGGAGAGAGTTATGGAAGGCAGAGGTTCGTTCTCAAAGTGTGGTCCCCAGACCGGCAGCCTTGGCATCACTGGAAACTTGTTAAAAAAATACCCTAGACCACCAGGAATGGTGGTTTGTGCCTGGTAGTCCCAGCTACTCAAGAGACTGAGGAAGAAGGGTCACTTGAGGCTGGTAATTCAAGGCTGCAGTGAGCTATGATTGTGCACCACTGCACTCCAACCTGGGCAACAGAGCAAGACCCTGTCTCCTAAAAATAGCAAAACAAAAACACCCTGATCTACCAAATTGGAAACTCTGGGGAATGGAGCCCAGCAAGGTGTGTGGCACAAACCCTGCAGGTGGAGCTGATGCATAATTAGTTAAGTGTGAGAACCACTAATCAAGGAGCTCTCGCCAGCCTAAGCATGGCAGGAGGGCCTGAGGACACATGCATGAGCATCCAGGGGGCTTCCCTCACCCTTCCTGCCGGCAGTTAGTCCCAAAGCCTGAACCACTTGTTCATGCTCTCTTTGACCTATTTAGATACAGCCAGCATGATAGTGATTTATGTTTGAATATTGTCATATTGAAAATACTGTTGGATATTGCATCTCATACGATGCAATAGCTCTATGAAGTAGTCCTAAGAGATGCCATTACGATCGTCTTACAAGTGAGAAAAACGAGGCTCTGAAAGGTTGAATGACTTTTTGGAAGTCGCCTTGCTAGAACTGTGCAGAAACAAGACCCTCAGTCTACTTTCTTGTATGCCACATTGTCCCCAAGGCTCACATGCGACAATTCGCTATTGACTCATACAATCTGCTGAAAGGAAAGAGGAACTCTTACTTTAGCACTTAGAAAATAATGAAGCACAGTCTCACACTGGGTTATTAAAAAGTTAGTTCAGAGGCCAATGGATTTGCAAAATAGTTGCTAGCTTATTTGCAAATGTTTACTGCTGCTACCCTGGGGAAAAAGCTGGCTTTTCACATCATCTCTTTCTGCTTCAG
Seq C2 exon
ATTGTGTTAATGGTCAACTTCTCCTCCCGCACCACGTCCATGGATATCCAAAGAAATTTAGAAGCAAATGTGGAAAAGCGAACCAAAGATACTTACGGCCCACCCATGGGAAAACGCCTGCTGGTGTTCATGGATGACATGAATATGCCAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:44
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.061 A=NA C2=0.176
Domain overlap (PFAM):
C1:
PF127752=AAA_7=FE(17.6=100)
A:
NA
C2:
PF127752=AAA_7=FE(18.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGATACCACTCGGACTACCTG
R:
CCTTGGCATATTCATGTCATCCA
Band lengths:
290-2245
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains