HsaINT1012246 @ hg38
Intron Retention
Gene
ENSG00000241404 | EGFL8
Description
EGF like domain multiple 8 [Source:HGNC Symbol;Acc:HGNC:13944]
Coordinates
chr6:32166138-32166620:+
Coord C1 exon
chr6:32166138-32166266
Coord A exon
chr6:32166267-32166497
Coord C2 exon
chr6:32166498-32166620
Length
231 bp
Sequences
Splice sites
5' ss Seq
GAGGTGACA
5' ss Score
3.85
3' ss Seq
ATCCTCTGGCATGGACGCAGTCA
3' ss Score
1.74
Exon sequences
Seq C1 exon
CCTGTAGGGTCCAGCGTCAAAGCGAATCATGGGGTCCAGGGCTGAGCTGTGCACTCTCTTAGGCGGATTCTCCTTCCTCCTGCTACTGATACCAGGCGAGGGGGCCAAGGGTGGATCCCTCAGAGAGAG
Seq A exon
GTGACAACAGAGGGGGTAGGGCCCGGGGTGAGCTCTTCTCAGGAGCCTTCTGCTGGGGGTGGGGCTTCACAGGAGGCAAAACATAACTGTAAGTTTAGAATGGGGGTGAGAGGCTGTCATCTGGAGGGAGAGCGGGGGGCCTCAGTAGCCTCTTGAGGGAAGTGGGACTCCTGGCTCCCCAGGGCCTGGCCTACTCAATCTCTCCCACCTCATCCTCTGGCATGGACGCAG
Seq C2 exon
TCAGGGAGTCTGCTCCAAGCAGACACTGGTGGTCCCGCTCCACTACAACGAGTCCTACAGCCAACCAGTGTACAAGCCCTACCTGACCTTGTGCGCTGGGAGGCGCATCTGCAGCACTTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000241404:ENST00000395512:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF075468=EMI=PU(0.1=0.0)
A:
NA
C2:
PF075468=EMI=PU(57.7=97.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGTAGGGTCCAGCGTCAAA
R:
CTGTAAGTGCTGCAGATGCGC
Band lengths:
252-483
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains