HsaINT1012935 @ hg38
Intron Retention
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177405323-177405805:-
Coord C1 exon
chr5:177405735-177405805
Coord A exon
chr5:177405434-177405734
Coord C2 exon
chr5:177405323-177405433
Length
301 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCTA
5' ss Score
2.48
3' ss Seq
CCACCATGTCCATCTCTCAGACC
3' ss Score
7.73
Exon sequences
Seq C1 exon
GTGTGCTACCACCCCCAACTTTGATCAGGACCAGCGATGGGGATACTGTTTGGAGCCCAAGAAAGTGAAAG
Seq A exon
GTGCTACACACAGCCTCTGGGGTGGCCTGGGGCTCTCTCCTCCCGCCTCATTACTCTCCTGGTATCACCAGACCCCACACACCTGGGATTCTGGACCCAGCCCCTTCTCTCCCTCCACAATACCCTTTGGAAGTCCAGAGGGAGAGTTCTGGGAAGGAGTGGTCCCATTTTGCAGGTGGGTAAACCAAGCTTGGAAACTTGGAGTAGCAAGGTCACAAGGCAAGTAGGTTCAAGAAGGGCCTTGGCCCCCAGCTGTGTGACTCAGCTCCCTGCTCTTCCTTCCACCATGTCCATCTCTCAG
Seq C2 exon
ACCACTGCAGCAAACACAGCCCCTGCCAGAAAGGAGGGACCTGTGTGAACATGCCAAGCGGCCCCCACTGTCTCTGTCCACAACACCTCACTGGAAACCACTGCCAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187:ENST00000253496:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.100 A=NA C2=0.283
Domain overlap (PFAM):
C1:
PF0004014=fn2=PD(38.1=64.0)
A:
NA
C2:
PF0000822=EGF=WD(100=84.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTGCTACCACCCCCAACTT
R:
CTTTCTGGCAGTGGTTTCCAGT
Band lengths:
182-483
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains