HsaINT1022857 @ hg38
Intron Retention
Gene
ENSG00000123600 | METTL8
Description
methyltransferase like 8 [Source:HGNC Symbol;Acc:HGNC:25856]
Coordinates
chr2:171326042-171330698:-
Coord C1 exon
chr2:171330559-171330698
Coord A exon
chr2:171326149-171330558
Coord C2 exon
chr2:171326042-171326148
Length
4410 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
3' ss Seq
TTAATACTTTGTTTCCAAAGGAT
3' ss Score
8.15
Exon sequences
Seq C1 exon
TCACACTCGTCCTACAGAGCAACCCAGTGTTTTGCCTTTGTTCATGATGTATGTGATGATGGCTTACCTTACCCTTTTCCAGATGGGATCCTGGATGTCATTCTCCTTGTCTTTGTGCTCTCTTCTATTCATCCTGACAG
Seq A exon
GTAAATGAAGACGAAAGGGCAAAGTGGATGTGTAAAGCTCCTTTATCAGTAGTGGTTTTCAGAACTATCAAAGCAAAAATGACAATTTTTGAATTTATTATTTAGTGAGCAACATTATGTATAATACACAGCCTTTTAAAGGCAGTTTTTCCTTTCTTCGTACTTTTAGACAGAAACTGGTCAGACTACTTCATTAATGAGCTTTCTGTCACTGTCAGAATGAAGTGAGCATATTCTGGCAAGACACATACCTATTAAAAGTGACAGTGCTTCAAGGAAATTACAAATTCAGAACAACCTAATAGACTCCCAAGAGGGAAATTGTACTTGGTGATCAGAAACAAACATCTTTAGTGTAGTGTCTTCCTGAATGTTCATGAAGAGGTGGGCTTGGGATCTGTTTGGCTTCACACAGGCCTGTTGATGGGCTTTAAAAATTTTGTTCTAAAGAAGCACACTAGGGAATCAGGAGTTATTAAGATTTGCCAGATTATCCTTGGACCTTTATGATCTAAGGTTAGCCTGATGCCATCATTTAAATATTTATGACTTAGTTTCATACAGTGTTTTAAAACTATAAACATAGCTTTTCTCCAGAGAGAAAACATAAAGAGATATTACCAGCAATTAGAATGATTACCTTTCTTAAATCTTGCCATCTTCTATGTATTAAAGGGTACATATGGTAAGTACCAGGTCTGTGCTTTCATAAGGTTTCTTAAAATTGGGTTCTCACAGTTCCCTGGTGGAAGATACAGACTTGGCGTCAACCACTTTTTGTTTGATGAGTGTGACCCTTTTCCATAGAAACTGAGTTACCATGTGCTTATTTCTTTGCAATTAAAAGGCCACTAGGACCCTTTACAGTTCTTTTACTTCCCATTCAGAAATGAGCACTTTGATTACTTGTAGAAGAACAAATTCCATTTCCAAATAAATCTGAAATAAGATACTTTAGCACCTAGTGAGGTATGTCAGGTTTTATGAAGCTACTGTTTCCTCCCAGTTTCTATAACCTATTTCTTTCTGCTAATCTGTTTAGACTGTAGGCATTGTTCAGGTACTAATAGAAAGTTGTCATCTATGTGTTTGGTTTCCTTATATGAACAGTTAAAAGGATGGAGAGGTGGATAGAGAACAAGATTCCCCATTGACACCCATAACAAGAAACATCTAAATTCTACATATAACCACAAAAAGACTATTTGAAATTAGTTCAGATAATGTATTTTCTCATGATTTGAATTGAATGTTATAGAGAAGAGAAAGGCCAGGTGCAGTGGTTCACACCTGTAATCCCAGCACTTTGGGAAGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCCAGACCAGCCTGGTCAACATGGTGAAACCTCGTTTCTACTGTGAAACCTCTGCCTCCTGTAGCCAGGCATGGTGGTGGGCGCCTATAATCCCAGCTCCTTGGGAGGCTGAGGCAGGAGAGTCGTTTGAACTCAGGAGGCAGAGGTTGCAGTGTGCCGAGATTGCACCACTGCACTCCAGCCTGGGCGACAAAGCAAGACCTTGTCTCAAAAAAAAAATAAAAGGCTGGGCGCTGTGGCTCACGCCTATAATCCCAGCACTTTGGGATGCCAAGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACCAAAAATACAAAATCACCTGGCTGTGGTGGCACACACCTGTAGTCCCAGCTACTTGGGAGGCTGAGACAGGAGAATTGCTTAAAACTGGAAGGCAGAGGCTGCAGTGTGTGGAGATCATGCCACTGCACTCCAGCCTGGGCAAGACAGAGACTCCGTCTCAAAAAAATAAATAAATGATAAAAATACAAAAATTAGCTGGGCGTGGTACTGCATGCCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCACTGGAACCCAGGAGACGGAGGTTGCAGTGACCCAAGATCACGCCACTGTACTCTAGCCTGGGTGACAGTGAGTAAGACCCTGTCTCAAAAAAAGAAAAAACTAAAACCAAGGCAATGTCTATAGTGTCACTTAGGACTATAGTAGTAGATTCAACCCCAGAAAAGTTCTAGAAAAGTAGCATCTTGGTAGCTTGGAAAATTCAGGCATAAGCAAATGGCAAGCAATTTGGCTAGACCTTGAGTCTGGAGGACCCAGCTTAAATGGGAATAAATTGTAGGTGGCTACAAAAGAAGAGCGAATTGTCCTTCTTGTCACTGAAATGAAAATACAAAATATTACAGAGCCAAGCATAAAGCAGGCAGTCAATACATTTTTTATCTCTTCCTTCTCCTCTCCCTCTATCCAGAGATAAGTGAAGACAGCAGAGTTGGCCCAAGTAGGATGAAGAAAGAAAAGGGGCTTCATACCATTCCTGTCTTGTCCATCTCACCCCCAGCCCACTCCCACCTGCAGTTCTCAGGAATTGGCTCGGGAACTGCACTATGAACCAAGATGAGATGAGCAAGAAAAGTAGCTCCCGTTCCTTGCCTTTATCCTCAACCCCAGACATTAAAGGATAGCTGAGAGGAAAGAATTTGCAGGAGGAGGTGGCTACATTTTAAAGTGTTCGATTGTTTATTTTTCTGCATTTTAGTTTCATACTTGTTTTACTAATAATTACAGAAAGATTTTGCTATGTACGTAAAATATTTATATTGAAAGTGAATATTTTAAGGTTTAGATATGATTTTCTTTCATTCGCAAAGCCTATGATATAAGCACAGTATGAAAATAACCTGTAATAAAATAAACAAAAAATACGTTTCTTTTTTCTTTTATGTCCTTATGTGCTAGTTTTTTTAAAAGGACTTTTCACCTAATCATGCCACCTCCTTTTGTCCTACTTCTTTCTTGTTTTATAGTTGCTTTCATTTTCTCAGTATCTGCTTCCTTCATAACATGACATAATCTGAGTTTTACCTTACTATTCCACTGAACAGTGTTTTAATTGAAAGGAATTTACAGATTATCTGATTCAAACTTTTCATTTTTTTCAAATAAGAAAACCTCAGCAGCTTTAAGTAGCTTAGATAAGGCAGAGACAAGGACTTAGCACACAAGCTGCCATTTACCATTCTCTGCCCATGGCAGACATTGATAATCGATTTTGTACTCGGTAACTCGCAATGAGCTTTATGAGTCCTTCTCAGAGCTCTGTAGGCAGCCGATGCTGTCACTCAGAATTAATATGAGATCTGAAATCTATGCCATCCCTGGCCCATAATCACACATAAAGCCATGAACACTTAGCCAAAAACACTAAATCAAGAGCAGCTATAAGGGATTGTATTTGACTGGAAGCCAAATAAGTAGAATAAACAGTAAAGGAGAAAAGCAAAGGCTCCCTGCTGTTGAACTAGGGCTTGGAATGTGAATAAAATTTAAATAGGCAGACAGTAAGGAGGAGAGAATTCTTTGAGGAAAAACCATGTGAGCAAAGGCAGAGGCTGCTCAGGGCCAAGCATGACAGTTTGGCTAGGGGAGCTGCTTCAGATTGGAAAGCTGTTGGTAAGATTAATTGGGGTCAGTAGTAGGAGATCTTAAGAGCTCAACTAAGAAATTGAAATTTTATCCTATGGATTAAAATCATGAAAGTTTTTGAGCAAGGAGATGATTTGACAAAATTATCATTTTAAGCAGAATTATTCATCGATAACATGCAGGAAGGATTGACAGGGAGAATAATACAGCGTGTTAGGAAGCAGATTTGTTTCCAGGCCTAAGGAGATAGGGGTTGGTACTAAGGGAGTACAAATGGGAAACAAAAAAGACAGGAAATATCAAAGATGTCATTAAAAATAAAAATTAAAGAGGACATAGAATTTTATGGCCACATGGAGAGGACAGTGGAAGAAAAATAATTTCTCTTTCATGAGGTAAATGGTGGTACCTCCGAACTAAATAAAGAAAAGGAGAATGAGCTCGTTTTGGAGGAAAGATATTCCCTCTTTAGATATGTACAACTTGGGATGGCTTTGGCATATTTTTTATCTTGCAAGGAAAATGAAGCACACTCCATTGTTGTCTATCTCAGAACTACCTTAATTTTCTGTAAGTACCAGGAAACATCTGTGGTTTTGAAGTTTAGCTTTGACATCATACGTCAAGCTCTGTGAAGTTACCACTCTGATCATTTGGGTGATTTCTTGATACTCTAGGACTTTTGAATCTAGTCATTTAGCAAGTTGGTTTTGGTTTTTTCTTCTTTACAAAATATTTTTATTTTTGTTACCCTTATGTTTATGGTTTAGATTTCTTTGGCCTTATCAAGCTTTTCTTATTTTGTCTTCAACAAAGTTAAATCCAGCATATAAAACAAGATTTCTACAAACTGGGTATCTTTTTAATACTTTGTTTCCAAAG
Seq C2 exon
GATGCAAGGTGTTGTAAACCGACTGTCCAAGTTACTGAAACCTGGGGGAATGCTGTTATTTCGAGACTATGGAAGATATGATAAGACTCAGCTTCGTTTTAAAAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123600:ENST00000375258:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF082427=Methyltransf_12=FE(43.8=100)
A:
NA
C2:
PF082427=Methyltransf_12=PD(17.1=48.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains