HsaINT1023992 @ hg38
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516]
Coordinates
chr11:1236925-1239541:+
Coord C1 exon
chr11:1236925-1237164
Coord A exon
chr11:1237165-1238870
Coord C2 exon
chr11:1238871-1239541
Length
1706 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
3' ss Seq
CACCTTGGCCTCACCCGCAGGTT
3' ss Score
9.39
Exon sequences
Seq C1 exon
GGCAGGGTCTGCGGCCTGTGCGGGAACTTCGACGACAATGCCATCAATGACTTTGCCACGCGTAGCCGGTCCGTGGTGGGGGACGCACTGGAGTTTGGGAACAGCTGGAAGCTCTCCCCCTCCTGCCCGGACGCCCTGGCACCCAAGGACCCCTGCACGGCCAACCCCTTCCGCAAGTCCTGGGCCCAGAAGCAGTGCAGCATCCTCCACGGCCCCACCTTCGCCGCCTGCCGCTCCCAG
Seq A exon
GTGGGGCTCTGGTCTTGGCAGGCAGGGTCTGGTGGGGATGGCAGTTGCTTCCTTCCCGCCGAGAACTGGGTCTTCTGGGCAGACAGCAGCGCTCCAAGGAGGGTCTGACCATGTCCCACGGCACACAGTCCTGGATGTCAGGTCCCAAGTCCGGATCTCCCGTCAGCCCCACACCTGTGCCTCTTGCCCCTGGCACGAAGCCATCTTGGCTGTTTCCCGGCCACTCCTTTGACCACAGCCTCAGTCACACCCAGAGGCTCACAGGGAGGGGCAGCCCTCTATGTGGCCCCTAGCCACCCTCCTCTATGATCCCCAGACCTGCCCAGTCCTCAGCACAAACTGGAATGCCAGCCTGGCTCCCCGCTCAGCCAGGGAGGAATCAGAGATCTGCCCTAAGCAGAGACTTCCAAAAAGCAGTTTCCTGACTGGGCGCGGTGGCTCATGTCTGTAATCCCAGCACTTTGGGACGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCGAAACCCCGTCTCTACAAAAAATACAAAAATAGCCGGGTGTGGTGGTGTGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAAGAGGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTAAGCAAAAAGAGTGAGACTCTGTCTCAAAACAAAACAACAAAAAACCAAAAAGCAGTTTCGTGTCATCTTAAGGAAGACTTGAGTGCCCACTTAGGCACACAGCATGGTGGCTCAGGAGCTGAGATGAGGGGCTGGCGTAGGGGCAGCAGTGGGCATACTCGCTCGTGGGAGGCCCTGAAGCACTCTCATGTCGGCCGCCGCTTGCCCTCTTGAGAAGGCAGCTGGTGACCCCTTGGAAGGTCCTGTGGCCTGACAAAGCTGAGCCCAGGTTCAGATGGGGCCTGGGAGGGGTGTGGGCTGCCTGGAGGAAGCAGGCAGCTTCCCATGGTCAGGACGCATTCACAGCTCAGCTCCCCGCGTGGCTGGTCTGGAAAGGAAGTGACCACTCCTTCCTTAGTGCACATTCACTGGGTGCCTGGAATAGCCTGGCATGTTCTGGGCTCACCCCAGTGATCAGGGGACGAGGCTGACCCTCACAGAGCTTCCAGAGGAGGCAGAAAGGCGGTGGGTGCTGGGTGGTCGGATGCTAGGATGTGGAGGGCCCTGGCCGGGGGTTGGTTCCGCTGGAGGGAAGGCCCCCAGGTGGAAAGGAGGCCAGTACGACTGCAGCGGAGGGAGGTGGGGGCGAGGGCAGAGGGTAAGCAGGGGTGCTATGCTCCACATGGGTTTGAAACCTGTGGGCCACATGACCAGATCCACGTGATAGAAAGATCCAAAGAGCACATGTGAAGGCAGGCAGATGGGCAGGTGCATAGGTGGGCAGGTGCATAGGTGGGCAGATGGACAGGTGGGCAGATGGGCAGGTGGGCAGGGATATAGGTGGACGAGGGCACAGGTGGGCTGGAGAAGTGCTGGGGCAGCTCCCATTTGGGGCACGCTCTGAGGTATTCCAGGCCCCAGGAGCTCAGAGAGCTGCCATGGGGGGTGTTGAAATACAGATGGTTCCAGCAACTGGCCCTGGGCCAGCCACCCCCTGGCCGGGGGGGCCATTGTCCCGGCTGAGCTGCACCTTGGCCTCACCCGCAG
Seq C2 exon
GTTGACTCCACCAAGTACTACGAGGCCTGCGTGAACGACGCGTGTGCCTGCGACTCGGGTGGCGACTGCGAGTGTTTCTGCACGGCTGTGGCTGCCTACGCCCAGGCCTGCCACGACGCGGGCCTGTGTGTGTCCTGGCGGACTCCGGACACCTGCCGTGAGTCGGGCTCTGTCCGTGGTGCTGAAGGGTGGAGCTGCTGGGGCAGGGGAGGAGGTGTGGCAGCCTCCGAAGGTGCATTGACCTGGGCCTGAGCCGCACACAGACATCCAACACGCATGTGCCTCCATGTGAGTGCACAAGTTTCTATGCACAGAGGAAGACCTGTGCAAAACCACCAGACAGGTTGCCCCAGCATGAGACAGCTCCTAGGGGACAAGAGTTCCAAGGGCAGGGCTGGGGAGTGGAGGGGAAGGTGAGGCACCACCCGGCCGAGGCCCTGCATGTCTGGGACAAGCCCGGGTCTGGCTCTGGGGACACCGGCCCCCACGCCCGGGGTAGGGGCTGCCCTGCACAACAGGGGTGAGGGCTGGTGGGCGCCTCCTTAGCCTCTGCCCTCTGTGCCCCAGCCTTGTTCTGTGACTTCTACAACCCACATGGGGGCTGTGAGTGGCACTACCAGCCCTGCGGGGCACCCTGCCTAAAAACCTGCCGGAACCCCAGTGGGCACTGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983:ENST00000525715:25
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0009420=VWD=PD(15.4=28.8),PF087426=C8=PU(28.0=26.2)
A:
NA
C2:
PF087426=C8=FE(69.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACTGGAGTTTGGGAACAGCT
R:
CTTCAGCACCACGGACAGAG
Band lengths:
342-2048
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains