HsaINT1024144 @ hg38
Intron Retention
Gene
ENSG00000133020 | MYH8
Description
myosin heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:7578]
Coordinates
chr17:10404330-10406177:-
Coord C1 exon
chr17:10406041-10406177
Coord A exon
chr17:10404586-10406040
Coord C2 exon
chr17:10404330-10404585
Length
1455 bp
Sequences
Splice sites
5' ss Seq
GAGGTAACA
5' ss Score
8.1
3' ss Seq
ATATTTTCATGTCATCGCAGAGA
3' ss Score
6.48
Exon sequences
Seq C1 exon
GTTTTCTTCAAAGCTGGACTTCTGGGTCTTCTGGAAGAAATGAGAGATGAAAAATTAGCCCAAATTATAACAAGAACACAAGCTGTCTGTAGGGGATTCCTAATGAGGGTAGAATATCAGAAGATGTTGCAAAGGAG
Seq A exon
GTAACAATCATTCAGAATATCAGAATTATAAGGTCCCTTAAGGACTATCAATCAGTCTTGTTCATTCATTAATTCTTTCATTTGGTGGCTAATAGTTCCTCTCACCCAATTCAGAACTCACTCCTACAACACAGCAGCCTTTGCTTCAGCTCTCACACTTGGATTCCTTTCAAAACTTCTCTCCTACCTCCAGCCATCTCACATACAGCCACAGGAATAGTTTGCAGTAAGCAGTATTTTCATCAAGCTAGTTGCTTGCTTGCCTGTCAAGGCCCTCTCTATTCCCCACCTCATCTATCATTTCCAAGCACATAGCCTTTTCCAGCCAGGCTAAACAATTTGCTTATCTACTAATCTCTCATTTGCTTATCTTCTTATCTCATCTCTCCCCTCATCCTAATTTATCTATTTACCAATTTAAAACTTTAATTTCCCCTTTCTGTAACTAATCTCACCCAGTTTATCTACCCAACACTATTGCATTCCCTCTACTTACACACACACTGTGCATTCATTTTTCTTATCTGTAATCATTTAGGCCTGCACTGGAAGTGTTCCTGAGTCTTTCCCATGTGTGAACGTTATGGTTTGTGTCAAGGTATCTGCTTTCATAGAGTTACAAGTCTTAAAAACTGGACCTATAGAGATAGAATTTCCATTTTAACAAGCTTGAAGAAACATACACATTGCTACAAGTAGTCAAACCTAGCCAGTCTATGGCTATAGTTTGCAGTAGGGGTACCTTTTATTACTATTTTTCACTTTATTTCAATAAAATAAATTTTAGAGCTCAACAGATGCTGAATGCCTCGCAAATATTAACAATCCAATTAATCAGTTAAGACTGAGGCACTTGAAAGAATTTGAGATAAGCCAGTGTATTATCTGAAGAAGCTAGCAAAAAAAGTTTATAGAGTGGATAATTCAGTGTTGTTCAAAATAAGAGGAGCAACTTCAAGGAAGAGATGACAAATCATTCGCTCAGTTTAGGTGGGCCATTCAGAAGGCAACCTATGTCATTTCACAGTTCTCATCCATATGCCCACAGACAGGCAGCACAATCAACATGCAATCACCATGCCCACCCTCAAATCACTAATACTGTCATATGTCAAATGGTATGTGCTGATCATACATTCAAAATATTCACCCCTAAAGTCACTCTCTTGGCTAGTTTGATAGGGATTGAGAACACAGAAGATGTGCTCAATATGAACCGTACTCATATTAGCAAAGTGGTTATACTGAGGGCTACTGACCATGAGTGTGAGCGCGAGAATGTGTGTACATGTGTGTGTGTGTGTGTGTGTGTGTAAAGCCTGCATATAATATATAGAGAATGTGACATATTTATTTGTGAGCGGCATTCATTAAAAGGGAAATTTGTGTGTGATAAGTAACAATAACATTGGCTCTGATGGATTAGTCTACACTGATATTTTCATGTCATCGCAG
Seq C2 exon
AGAAGCACTTTTCTGCATCCAGTATAATGTCCGTGCCTTCATGAACGTCAAGCACTGGCCCTGGATGAAACTCTTTTTCAAGATTAAGCCCCTCCTCAAGAGTGCAGAGACCGAGAAAGAGATGGCCACCATGAAGGAAGAATTCCAGAAAACCAAAGATGAACTCGCCAAGTCAGAGGCAAAACGGAAGGAGCTAGAGGAAAAAATGGTCACTCTCTTAAAAGAGAAAAATGACCTGCAACTCCAGGTTCAATCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133020:ENST00000403437:21
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.151
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.4=6.5)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTTCTTCAAAGCTGGACTTCTGG
R:
TTTTTCCTCTAGCTCCTTCCGT
Band lengths:
342-1797
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains