HsaINT1024311 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77184588-77189470:+
Coord C1 exon
chr11:77184588-77184715
Coord A exon
chr11:77184716-77189343
Coord C2 exon
chr11:77189344-77189470
Length
4628 bp
Sequences
Splice sites
5' ss Seq
CCGGTCAGT
5' ss Score
7.53
3' ss Seq
TTGCCCTGCTGCCTGCCCAGGGA
3' ss Score
6.88
Exon sequences
Seq C1 exon
GTGACCAAGAGGCTGCATGACGGGGAGTCCACAGTGCAGGGCAACAGCATGCTGGAGGACCGGCCCACCTCCAACCTGGAGAAGCTGCACTTCATCATCGGCAATGGCATCCTGCGGCCAGCACTCCG
Seq A exon
GTCAGTGCCGGGAGGCGGGGACACCAGGGCCTGAAAGTCTTTTGGTGGCTGAGTGGTGCCTCTGTCAACCTAGCAAGAGATTAAGCCAAGCAGGCCTGGGTTTGGCTTCGCTGCTAGCTAGTTGGTGGAGTTAGGACCTTGGTGGAGTTATTTCATCTTTCTAAGCCTCTGATTCCTTGTCTGTAAAGGGGGAATCCTAAAACAGGCATCCCTTGGAGATATTGCAGGTTCAGTTGAAGGCCACAGAAATAAATATCACAATAAAGAGAGCTGCAGAAATATTTTGGTTTCCCAGTGCATATAAAAGTCATATTTATACTATACTATAGTCTATGAAGTATGAAATAGCATTATGTCTAAAAAATGTAGACATCTTGATTAGAAATTAATGCCAAAAATGCTAATGGTCATCTGAAAGTTGTATCTATTTGCTGGAGGGTCTTGCCTTGATGTTGATGGCTGCTGACTGATCAGAGTGGTGGTTGCTGAAGGTCGAGGTGGCTGCGACAATTTATTAAGATAAGACAACAGTGAGATTTGCTTTCACACAAAATTTCTCTGTAGCATGCAATGCTGTTTGACAGCATTTTACCCACAGTAGAACTTCTTTCAAAATTGGAGTCGATCCTCTCAAACCCTGCTGCTGCTTTATCAATTAAGTTGATGCAATATTCTAAATCCTTTGTTGTCATTTCAACAATGTTCACAGCATCTTCACCAATAGATTCCATCTCAAGAAACCACTTTCTTTGCTCCTCCATAAGAGGCAACTCCTCATCCACTGAAATTTGATCATGACATTGCAGCAACTCAGTTCCATCCTCAGGCCCCACTTCTCATTCTAGTTCTCTTGCTATTTATTTCCACCACATCTGCAGTTACTTCCTCTTGAAGTCTTGAGCCCCTCAGTCATTCATGAAGTTTGGAATCCACTTCTTCTAAACTCCTATTGATGTTAATAATTTGACCTCCTTCTACGAATCATGAATGTTCTGAATGGCACTGAGAATAGTGAATACTTTCCAGAAGCTTTTCCATTGATTTTGCCCAGATCCACCAGAGGAATCACTATCTATGGCAGCAATAGTCTTATAAAATGTATTTCTTAAATAAGACTTGAAAGCCAAAATTACTCCTTGATCCATAGGTTGCAGAATGGATGTTGCATTAGCAGGCATGAAAATAACATTCGTCTCCTTGTACATCATTTTTTTTTTTTTTTTTGGAGACAGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCCATCTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTGGCTGGGACTACAGGTGCCCACCACCACATCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGCCAGGCTGGTCTTGAACTCCTGACCCTGTGATCCACCCACCTCAGCCTCCCAAAATGCTGGGATTCCAGGTGTAAGCCCCTGCAGCCAGCCTCTTGTACATAATTTTTAAGAGCCCCAGAATTTTTGGAATGGTCACTGAGCATTGGCTTCAATTGAAAGTCAGCAGTGCATTAGCTCCTGACAGGAGAGTCAGCCTGTCTTTTGAAGCCTTGAAGCCAGCCATTGACTTCTCTCTAGCTATGAAAGTCCTAGATGACATCTTCTTCCAATAGAAGGCTGGTTCATCTACATGGAAAATCTGCTGTTGAGTGTAATCACCTTCATCAATGATTCTAGCTAGACCTTCTGGAAAACTTGTTGCAGCTTCTCCACCAGCACTTGTTGCTTCACCTTGCACTTTTATATTTTGGAGACAGCTTCTTGCTTTGAACCTCATGAGGCGATCTCTGTGAGCCTCCAACTTACCTTCTGCAACTTCCTTACCTCTCTCAGCCTTCATAGAATTGAAGAGACAGTCTTCCTCTAGATTAGGCTTTGGCTTAAGGGAATGTTGTGGCTGGTTTGATCTATTCAGACCCCTAAAATTTTCTCCATATCAGCAAATAAGGCTGTTTCACTTTCCTATCATTTGCATGTTCACTGGAGTAGCATTTTTGATGTCCTTCAGGAACTATTCCTTTGCATTCACAAGTTGGTTAACTGCTTTGCACAAGAGGCCCAGCTTTTGGTCTATCTCGGCTTTCAACATGCTTTCCTCTCTAATCATTTCTAGCTTTTGATTAAAAGTGAAAAATGTGCGACGCTTCCTTTCACTTGAACACTTAGAGGCCATTTTAGGGTTATTAATTGGCCTAATTTCAATATGAATGTGTCTCAGGGAATCAGGAGGCGTGAGGAGAGGGAGTGAGATGGGGGAATGGCTGGTTGGTAGAGCAGTCAGAACACATCTAACATTTATCAGTTAGGTTTGCCATATTCTATGGGCACGATTCATGGTGCACAAAACAATTACAATAGTAACGTTAAAGATTAGTGATCACAGATCACAGCAAATATAATAATAAAGTTTGAGATATTTCTAGTATTGCCAAAATGTGACAGAAACGGGAAGTGAGCACATGCTGTTGGAGAAATGGTGCTGGTAGACTTGCTCCATGCAGAGTCGTCATAAACCAATTTGTAAAAAATGCAATGTCTGCAAAGTGTAATAAAGTGAAGTACAGTAAAATGAGGTGTGCCTGCAGTAGCTACCTCATACATAGGCTTGTGGGAAGATAAAGCTATGAAAACTGTGTAGCACCAGACCTGGAGCATAGTAAGCGCCCCGTAGATGGTAGCTTTGATCATCATCATCCAACATGCATTTCCTGCTTTAACCCCGCTGCCGCCAGCTCACCTCCAGTCACCCACCCTAGGCCCACGGTTAAGGTTACTGTGCCTGGGAATCCTGCAAGTACCTCCTTCCCCACAGGGCCAGGAGAGGCCTTTACCCAGGTCCCTGGGGTTTTGGGGAGTTGAAGGGAAGACCCAGGAGTCACCAGGAGCCACCAAAAAATCAACTCAGCTGATGAGAGGAGGGCTAGGACTTTTCTGAGAACAGTCTCTGCATAGGACAGGTCTGTCGGGAGAGCTGATGCCATGAATGTGTGCATGCTGGTTGGGAGGACAGCAGGATGAGGCAGGGACCAAGCCCCACTTTCCTGATGGGGAAACTGAGGTCCAGAGTAGGGAAGAGATTTGCCCAGGGGTCACTAGGCCTCCTGCCTCCTATCAGGCCCCCGTTTTTATCTCCCCAAGGCTAGTCACTACCTCACCGGGGTGGCCACACTGCCCAGGGCCACCTGCCAACAGGAGGAAAAGGCAGCTGCTGCAGGCGTGTCTCAGGGGCAAGAATTTGCCTCCAAATTATCTCACCATCATACCTAAAGCTGACACTTCTAGGAAACACGGTGCCAGGAGCCCTGAACCAAGAGTCCAAAGGCTGGGGTGTCAACTCCTTGAGGGGCCTCACACGGCTAATCCCTCCCTGCTCTCAGCCTCTGTCTCCCCATCTGTAAAGTGAGTGGAGACTCCCAGCTGCAGGTGATAATATCTCACTAGTCTGTGGCAAGGTGGGAAAAGGAGGGATGTTTCTGAAGCTAAACTTGTTTTCTTTAAAGGACTGCTCTGAGACTTTGCCCTCCTACTGTTTGGAAATTTAAAATTACCTTTGTTTTATGAGATAATTGGGATCTAGATAGTGGGCAGGTTGTGTGTGTTATAAATGTTCTCATTTATCATGATAAAAAAATGGGTAACTTCAGAATTTTCTTTGAAATTATAAACTCTCAAAACTGTTGAGCCACTGAATTAGGTAATCCCAGCCATCCTTTGGGAGAGAAGAGCAGCAGTGAGTGCCCCCTGGCGGACACTGCATCGTCATGTGTCCTGCCCTTGTCCTTGAACAGGCAGGCTGCAGTCTTAGAGTACTCAGTTTGCAGAAGAGAAGAACAAGCCCAGCAATAATTGCAGCTGGCATTTATGAGGGGTTCACTGTGCCTGGCACTGTGCTAGGTGTGTCATAAGCCTTGGCTCATTCATCTTCACAGCAATCTTGTAAGGATTCCTTTAAAATGAACACCAAAAAATTACCTTAATTGTTTTCATCCCATTACAAAAGTCATACATGGCCCCTTAAGTATTCACACATTACAGAAATATACCAGAGACAAAGTCCCTACTCATTCCATCCCCCAGTGACACCCCAGGATGCTTTTCCTGTTTCCGCTTTGTCCGTTGCCATGGGTAGAAGTTGCACCTGCTGCCGTGACTATGGGCTGGGATCAGAGAGGCGAACTCACCTGCCTGGGCCACCAGCTGGTTAGGAACGAGGCAGAGGCGGGGACTGTGCTTCTCATTAGCATGGTCACCTGTGGCTGTGGCTGCGGCTGCTGAGCCCAGAGCAGGATACGCACCACCCTGGATGGTGGGGCCCTGGCTGTGGGAACTGGATTGGAGTTGGGGAGGTGCTTTATGCCCGATGATCCTGTCTCCAAAGCCAGACCCCAGCCCTTGGCTCAGCCCTGCCACCCAGCCTCACTCTGCCTCCTCCCGGGTGGTCTTGGCAAGTTGGAGAGGACAGCTGTGTGGCGTCCCACTGGCTGCTAGGAGGAGGTGGGGACCGGGGCTGTTCCTGTGGGGTGATTCCCCCTCCCTTGCCCTGCTGCCTGCCCAG
Seq C2 exon
GGACGAGATCTACTGCCAGATCAGCAAGCAGCTGACCCACAACCCCTCCAAGAGCAGCTATGCCCGGGGCTGGATTCTCGTGTCTCTCTGCGTGGGCTGTTTCGCCCCCTCCGAGAAGTTTGTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:27
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.471 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=PU(18.9=46.5)
A:
NA
C2:
PF0078412=MyTH4=FE(39.6=100)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains