HsaINT1024313 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77199535-77201638:+
Coord C1 exon
chr11:77199535-77199818
Coord A exon
chr11:77199819-77201447
Coord C2 exon
chr11:77201448-77201638
Length
1629 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
3' ss Seq
CACTCACCTCTGCTCTACAGCAG
3' ss Score
5.4
Exon sequences
Seq C1 exon
GGAGTGCCGTGTCTGGCTCTCACTGGGCTGCTCTGATCTTGGCTGTGCTGCGCCTCACTCAGGCTGGGCAGGACTGACCCCGGCGGGGCCCTGTTCTCCGTGTTGGTCCTGCAGGGGAGCGAAAACGACGGCCCCCAGCTTCACGCTGGCCACCATCAAGGGGGACGAATACACCTTCACCTCCAGCAATGCTGAGGACATTCGTGACCTGGTGGTCACCTTCCTAGAGGGGCTCCGGAAGAGATCTAAGTATGTTGTGGCCCTGCAGGATAACCCCAACCCCG
Seq A exon
GTGAGTGGCTGCTGGTATGGACTGCCTGGCACTGGGGGTCAGGGTGTTATGCAGACTGTCTTAGTCCATTTGTGTTGCTATAATGGAACACTGGAGGCTGGGAGATTTATGAAGAAAAGAGGTTTATTTGGCTCACAGTTCTGCAGGCACTACAAGAAGCATGGTGCTGGCTGGGCACGGTGGCTTATGCCTGCAATCCCAGAGCTTTGGGAGGCTGAGATGGGAGGATCACTTGAGGCCAGGAGTTCAAGACCAGCCTGGGCAACATAGTGAGACCCTCGTCTCTACAAAAGGTTAAATAAATTAGCTGGGTGTGGTGGCATGTGCCTGTAGTCATAGCTCTTCAGGAGGCTGAGGTAGAAGGATTACTTGAGTCCAGGAGGTGGAGGCTGCAGTGAGCCATGATTGTGCCACTGCAGTCCAGCCTGGACAAGAGTGAGACCTCCTCTCTTAAAAAAAAAAAAGAAAAGAAACAAAGAGAAAAAAGATGGCACCAGCATCTGCTTCTGATGAAGGCCCCAGGAAGCTTCCACTCATGGCAGAAGGAGAAGGGGTGCCTGCATCAGAAGGAAGGAAGAGAGCAGGGGGTGCCAGGCTCTTTTTAAACAATCAGTTCTCACAGAGACTATATAGAGTGAGAACTCACTCATTACCGTGAGCACGGCACCACACTGTTCATGAGGGACCCACTCCCATGACCCAAACACCTCACACTAGGCCACTGCCAACACTGGGAGATCAAGTTTCAACAGAGAGATTTGGAGGGGACAAATATCTAAACCATATCACAGACCATGCCCCGTGGCCTTGGCCTTGGCACTCAAGGCTGCTAGGATCTTGTTCCCATCTTTCCCCTGAAGCTAGACCAAATAGCAGAAGCCTGTGCCTTTAATCTGTAGCCTGTGGGGAACCTCTTCTCCCTCCCTTCTTCTGGCTCTTCAATACTCATCTCCTGTCAGCTCTCCAAGTTAGATCAGGGTCCTCCTCAGTGTTCCCAAAAGACCCACCATCTTCAAGTGATAACAGCAGTAACAACTACTCTGCCTGAGGCTACCGAGGCCCTGGCCAAGTGTGGGAAAGACAAAGATGAAATGGACCCCACCCTGTCCTCAGTGGGGAGGGGGGTGGGAAGAAGACAGTGACAGGCCTGTGACAGTGCAGTGAGCAGGGAAGCCCAGAGCCACAGGAGCCCAGAGGAGAGGCCCCATGCCGACTGGGGTCCAGGGAGGAAGCCCGTGTGACCAGAGCACAGGGGGCAGAGAGCTAAGCGTGATGCCAGCACAGAGGCGGGAGAAAGCTGGCCTGTCCAGGGAACTGCGAACAGCTTGGTTTGGCTGGGAACAGGCACAGTGAGGGAGGAGAGGCGAGGTGGAAGGAGTCTGGGAGGCCCGCTCACAACAGGCCCAGGAGTGTGGGGCTTCCTCCCAAGGGCAATGAGGAGCCGTGGAAGGCTTTTGAGCAGGAGAGTAGCCCACTCTGGTGATGGTCTCTGTATGGAGAGTTGTGACAAGGTGGAGGCAGAGTGGCAAGTGGGCAGACATGAGTGATAACACCTCAGTTCTTCTGTGGGAAGATGTTCCAACTCAGCCTGTCTCTGCCCCCATGGTCCCACTCACCTCTGCTCTACAG
Seq C2 exon
CAGGCGAGGAGTCAGGCTTCCTCAGCTTTGCCAAGGGAGACCTCATCATCCTGGACCATGACACGGGCGAGCAGGTCATGAACTCGGGCTGGGCCAACGGCATCAATGAGAGGACCAAGCAGCGTGGGGACTTCCCCACCGACAGTGTGTACGTCATGCCCACTGTCACCATGCCACCGCGGGAGATTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:35
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.031 A=NA C2=0.357
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF146041=SH3_9=PD(84.7=78.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTTCTCCGTGTTGGTCCTG
R:
GGGCATGACGTACACACTGTC
Band lengths:
355-1984
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains