HsaINT1028233 @ hg38
Intron Retention
Gene
ENSG00000188086 | PRSS45
Description
protease, serine 45 [Source:HGNC Symbol;Acc:HGNC:30717]
Coordinates
chr3:46743866-46744755:-
Coord C1 exon
chr3:46744643-46744755
Coord A exon
chr3:46744141-46744642
Coord C2 exon
chr3:46743866-46744140
Length
502 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGT
5' ss Score
9.25
3' ss Seq
GGGCTCTCTGTTTCCCACAGCAC
3' ss Score
8.61
Exon sequences
Seq C1 exon
ATGACCCGCCATTGGCCCTGGGAGGTGAGCCTCCGGATGGAAAATGAGCACGTGTGTGGAGGGGCCCTCATTGACCCCAGCTGGGTGGTGACTGCGGCCCACTGCATCCAAGG
Seq A exon
GTGAGTATGGCCCATGTGTGCAGGGCTTGGAGACCTCAAGCTACCATGGGCCCAGCCCAGCTTCCTCATTTCCTGAGTGAAACAGTGTGGGAGGGAGGTAGGGAGTGGGAAGGGCATCTGGGATAAGTGAGAATTGTGCTCGGGGTCTCCTGGGGGCCAGGGACTGAGCTAGGGCGGGAGCCCCTAGCAACAAAGACTGCACCCTAAGCTGAGCAACAGGAAAACCCAGAACACGCCCCCTACCCCATCACGCATGAGAGCATATGTGTACACCAACACTTCCACACCTGCACGCACAACACACAGACCAGGCCACCTTGAATCAATTTGAATGATGAATGAGGAGGCAGTCAGCTCTGAGATCTTCAGTGCCCTCAGGCTGGATTAGGCAGATTGGGTGGAGGCAGGACTCTTGCTAAAGGGGTAGGGCCACGGGGAGGTAGGAGTGTGTTCCTGCTTGGGAGTCTGATACCTACCAGGTGGGGCTCTCTGTTTCCCACAG
Seq C2 exon
CACCAAAGAGTACTCAGTGGTGCTTGGCACCTCCAAGCTGCAGCCCATGAACTTCAGCAGGGCCCTCTGGGTCCCTGTGAGGGACATCATTATGCACCCCAAGTACTGGGGCCGGGCCTTCATCATGGGTGACGTTGCCCTTGTCCACCTTCAAACACCTGTCACCTTCAGTGAGTACGTGCAGCCCATCTGCCTCCCGGAGCCCAATTTCAACCTGAAGGTTGGGACGCAGTGTTGGGTGACTGGCTGGAGCCAGGTTAAGCAGCGCTTTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188086:ENST00000620911:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(35.2=97.4)
A:
NA
C2:
PF0008921=Trypsin=FE(40.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCGGATGGAAAATGAGCACG
R:
CTGCTTAACCTGGCTCCAGC
Band lengths:
347-849
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains