HsaINT1028234 @ hg38
Intron Retention
Gene
ENSG00000188086 | PRSS45
Description
protease, serine 45 [Source:HGNC Symbol;Acc:HGNC:30717]
Coordinates
chr3:46742913-46744140:-
Coord C1 exon
chr3:46743866-46744140
Coord A exon
chr3:46743074-46743865
Coord C2 exon
chr3:46742913-46743073
Length
792 bp
Sequences
Splice sites
5' ss Seq
CAGATGAGC
5' ss Score
1.42
3' ss Seq
CACCCTGCTAGGCTCCACAGCCA
3' ss Score
-0.11
Exon sequences
Seq C1 exon
CACCAAAGAGTACTCAGTGGTGCTTGGCACCTCCAAGCTGCAGCCCATGAACTTCAGCAGGGCCCTCTGGGTCCCTGTGAGGGACATCATTATGCACCCCAAGTACTGGGGCCGGGCCTTCATCATGGGTGACGTTGCCCTTGTCCACCTTCAAACACCTGTCACCTTCAGTGAGTACGTGCAGCCCATCTGCCTCCCGGAGCCCAATTTCAACCTGAAGGTTGGGACGCAGTGTTGGGTGACTGGCTGGAGCCAGGTTAAGCAGCGCTTTTCAG
Seq A exon
ATGAGCAGGATGGGATGGGGGGTGGGTGCAGTACCACCGAGAGCACACTCCTTTCCTTCTGGGGCCTTTCCTGCTGGACCTGGTTCTCTGAATGTGTTGACCACTCCTCATGTGGTGACCATTGTCACTGTTTATGTGGACACCTCATTCAGGCCTGGTAGTGCCTGGGCTGGGCATGACCATCTGTGTCTTATAGAAGCTCAGAGCTGGGCATTCACTCATTCCTTCACTTGACACACTTTGAGTGTCGGCACCCAGCCCTTGGGATTAGAAATGCATGCCCTGCCTGGAGGGAAGTCATGATTGGGTGTGGGTGTGGGCACAGGCTGAGGAGAACAAGGCAAAGTTCTTGTCTGGTGGTCTTGAGATCCAGCTGGGAGGGATCTGGAATGAGCTCTGGGCAGAGGGACTGCCTTGAGGCCCTGGAGGAGGAGCGAGTGTTAACGAAGGTGGGGAGAGCGGCCGTGCCAGCAGAGCTGAGAGTCTGCAGGGAAGCAGCGCGGGGCTGGGCCCCAGATTGGAAGCGGCTGCACTGAGACTTGAGTTATGGCTGGTTTGGTTCAGAAGCAGAAGTTTCCCAAGAAGGGGATCTGGACTCAGAGCCTTCGAGGGCGGGGGCTTTTCAGACAAGGCCTGCACTGCAGGGGGAGGGGCCGGTGAAGGAGGGGAGGGCTTGGAGGTATGACAGGCGGTGGCTGGGCTGAGTCTCCAGGGTGAAGGGGACAGGACCCTGGACAGAGGTCAGGGTTGGGTGGAGTGAGAGGTCACTGCTCACCCTGCTAGGCTCCACAG
Seq C2 exon
CCAACTCCATGCTGACCCCAGAGCTGCAGGAGGCTGAGGTGTTTATCATGGACAACAAGAGGTGTGACCGGCATTACAAGAAGTCCTTCTTCCCCCCAGTTGTCCCCCTTGTCCTGGGGGACATGATCTGTGCCACCAATTATGGGGAAAACTTGTGCTAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188086:ENST00000620911:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(40.2=100)
A:
NA
C2:
PF0008921=Trypsin=PD(9.5=17.5),PF0008921=Trypsin=PU(53.5=94.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTACTCAGTGGTGCTTGGC
R:
CTTGTAATGCCGGTCACACCT
Band lengths:
348-1140
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains