HsaINT1028623 @ hg38
Intron Retention
Gene
ENSG00000119943 | PYROXD2
Description
pyridine nucleotide-disulphide oxidoreductase domain 2 [Source:HGNC Symbol;Acc:HGNC:23517]
Coordinates
chr10:98410939-98415184:-
Coord C1 exon
chr10:98415009-98415184
Coord A exon
chr10:98410959-98415008
Coord C2 exon
chr10:98410939-98410958
Length
4050 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
3' ss Seq
CCTGTCCCGTTTTGTTGCAGGAC
3' ss Score
11.75
Exon sequences
Seq C1 exon
CCAATCGCTAGCAAACTCCCTGCCTAGCAAGGCCCAGCCTGGGGCAGAAATGGCTGCAAGTGGCCGAGGTCTCTGCAAGGCTGTGGCCGCCTCTCCCTTCCCGGCGTGGAGACGAGATAACACGGAAGCCAGGGGAGGTCTGAAGCCTGAGTATGATGCGGTGGTGATAGGAGCAG
Seq A exon
GTAAAGTGGTAAAGCAGGCCGGGCCAGAGCTGAGGGGCGGGAAGACAGCCCTGCTCAGAGCTTGGTGGGGAGGGGGAGGGGGAGCCAAGCCCCACTGCTCTCTCCTCTGGCATAACCCAGCCAGAAGTTTATACGCTAGCAGGGGCTGCAATGGAAAGCCCTTCCATCTGGCAGGCAGGCACCTGGGATTCCGGTGCTGGCTCTGCTGTGTGGCCTGGGGCAAATGCTTGCCTTCTCTGGGCTTGGATCTTCCCATGGAGAATGACAGGAAGACTAGGTGAGCTCAGGGGTTTCCCTATATCTCTTGCAAAGTGACCTAGTTTCCACCACATTCTCAGCCTATGGTTTGTAAGGGTTGGAAAGAGCCCTGGGCCAACAGACAAGTGAAATCCAGCACCCCGCCCCCTCAGTGCCCTGAGTTCTGGTCACCACTACCTTACCACTGAGGCCACCCCTCGTCACAAGAAACTGCAGTCATTTCATAAAGGCCAGTTAGGATAAAACAGAACTGAGTCCCAGAGTTCCTACTGCGTGTCTGCAGAGGGAGATGGACCCCATTGCCTTGCAGCTCTGGGACATTTGGGGATCTGCAGTGATCTGCCACACTTTGCCAACCCCTGGGCTCAGAGTATCACAGTCTACTGGGTGCTAGGGGAAGAGGCAGGCCCAGGACCAGGTGGTCTTTCCTTAGTGCCTTCCTTTCACACTTGCAGAGGGCCCCAAATGCATGATTGCCAACTGGGTCTATACAGAGATAATGACGGGACCGAAAGCAGACGGCACTCAACATGCAGCTTTGAGGGCATGCCTTCATTTTCATATGTACTAGAGCAGTTGCGAGCTGGTAGATACTCAACACTCACCTCTCCAGGGAAAAATGTGTGATGTATGTGTGTGTGTACATGTATATATATGTATATATACACACATATATGTGTATATATATGTATATGTGTTACGTACATATATATACACATATACACATGCTTATTTTAAATATTGAAATAAAAGATACACTGCACACAATTTTACAAATAAAGATACAATACTCTCAATTTAAATGCAGTCTACCCGAGTGATTCTTACCAAAGGCTTTCTTTGATTTTTGCCAAACTCAGTAGCCAACCTATAGTTGCAAATGACAAATGAGGGTAGCTCCAAAGAGAACGGTGCTCCATATTTTCTGTAAAGAGTAGGATGATCGTGAAACAAATGAAACAACAAAGATTTATGTCCCAACCTTACTCCTTTATTTTTTAAAATTTATTTTTATTTTATTTATTTATTCATTTATTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGCGGCGCAATCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCGAGGCTGATCTCAAACTCCTGGCCTTGTGATCCACCTGCCTCAGCCTCCCAAAGGGCTGGGATTACAGGTGTGAGCCACTGCGCCCGGCCTCCTTCTTTAAATGACAGGAATGATGTTACTCAAATAAGATAATATTGTTCTAATACTAGAATATTTCCTTCAATTTTTGTGCTATTTATTCATGCTATAACAGCTAACACTGTTAGGTTTAATCTGCATTATTAGCATTTTCCCATCACTTTCTTAAGCCTGACCACAAAAAATAAATTCAGCCCTTCTGTGTAATATTTGCTGATGACAGTGGTGTAAATACTCCCACCATAGCCTTTTCTGTTACCAAGATGAGGTTGCTCAATGTGATTTAGGAGAGATACCCAGTAGCACATCATTGTATAGTGTGTCCACCATGCAGATATGTACATAGAGGCCAGTGACTGCCAGGGCATGGGCAACAGTCAAATGTAGTAAAACAAATAGGAGGTAGTGTGTTTTGAGTATTTATTACCTTTGTTTTTAATTTATTTAATTGTAAGCTTATATAATTTAGTTTATATCAATGGCTGTTTGACAGCCGGCTCACAAACTCCCCGGGCTGGTGGGAGCCATCTCCAGCACCTCACTTAGCCTCAGAGAAGCCCCCTGCCTCCTTCCGTGCTCAGCCACAGCTCACCCTGCTGTCTCCTAATGGGGAAGGTTGACTTTAGGTCACCAGCTGCCTTGGTGACTTGCCTACAAGTGCGAGTGAGTCTCAGTGTGTGAGCTTTTCCTTGACATGATTTCTTTAGTTGCTAAACATACCATAAAGCCTGGTTTAAAGGCATCTTGGGCCTCAGTGAGGAACAGAACGGCATCTTCTGAGACAAGGGTTACCTCTGAGTCCCTGAAGGCACACTGGCACCTGGCCGCCACCTTGAAGATGAATCTCATTTAGTCATTTGACTAAATGTGCCTGAGAGTGACTGAGGGGGCTTGTTAAAATGGAGATTCCTGGCCCCATACCTGGTGACGAGCATTCTGAGGGCGGGAGGTGTCTCCCAGAGGTCAGCACATCCACCCAACCAACACTGCCTGATGCAGGCAGCTGCAGAGCCCACGCCCAGAGCAGCTCCTCAAGGGCCCAGGCGCCTGCTATGGGGCCCCTGAGGCAGGTCTGGGGATTAGCAGAGCCCGCAGCTGAAGTCCTCTTCAAGGGAACAGAGGTGTCACCAGAAGCCAAGGAGGGCTCAGCCAGGACTTGAGGGTGGTCACTGGGAGGGGGTCTTGTGCTTTGGATCCTTGACCTTACTCATTTGAGGTCTGCCATGATTGAACTGGACCCAGTTGCCTGGAAGACTATGAGTTTTCCAAGATCGATCATCAGCACCAATTAAAAGACAAATAGCTCCCATTTATCTCATCCTTGCCACACTGCAGGGTCCCTGGCACCCTCTGTTCCCCATGTGAAGAAACTCAAGGCTCAGGGCAGCTGATGACTCTCTGAGGTCATGCCCTGGCAAATAGCAGAGGCTGGGCTGAGCCCAGGACTGTCTGCCTTTAGTTTGCTGCATGTCTTTGAGAGACAGATTCCATCTGTTCATGAGTCCCACTGGCGGATTGTTTAAACTTTCTTATGAACATTTTCAAAAGCCCATACAAATAAAGAGTATGTCAACCAGCACTTTTTAAGATGAACTGTAACCAACTAGCTTCTCACATGCTTCTCATATGGTAAGAGTTAATTTTAGCTCATGAAACTTTTGGTTCTGTGAAACACCTGCTGAACAGACTCCTGGGAAGGGGGTCTGTGGGAGTCGACATTTATACAACCTTCCAGGTGATTCTGAGCTTATCAGAGCTGGAGAGGCACTTGCTACCCAGGGGCTTGGTGTGGAACGTGAGATGCCAAAGCCAAATTCAGGCCTCTCAGCTCAAGGCACCCTGAAGCACAGCTAGTCACTCCAGCACATGTTGAAGCTGTGCATGTTTACTTCATGTTGAACTGTTCATGTTTTATTTTTGGAACACTGGGGATTGGCAAAAAAAAAAAAAACCCATGTGAATAAAGCCTTCTAGGGCACCACTGTGCCGATTGTGAACCACACGTGGACAAAACAAGCCGCGCTTGATAGCAACTACCTACATGACCAGCACTCCCCTGGATGCTGATGCTGCCATGCGAGACGGGACGTTGGCGCAGCAGCATGCCAGCCACCCATTGCTTCTCCTGCTTGCCAACTCAACCGTGCTGCTCCCTCAGACACCATCACTTGCGCCTCCCAAGCAATGGAAGCCCTGGCGATGCTCTCATGAGCCCCTCACTCCAGCAGAGCCCCTGACCAAGCCAGGGGAGCAGGACTTTTCCAGCCAAGGCAAGAACCAGGGTTTTCTGACTCCTTGAAGATCTGGTGTTTCATGGAGTTGAACTAGATGCTGTTCCAACATCTGAGTGCGGGAAGGGGAGGGGAGGGTCACCAAGGATCTTCATGGCATGGGGACGGGCAGCGGGGAGCACATTCCTCAAGGACTGTCTGTCTGCCCGCCCGCTGACCAGTGATGTTTTCCTTCCCTGTCCCGTTTTGTTGCAG
Seq C2 exon
GACACAACGGACTGGTGGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119943:ENST00000370575:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=NA C2=0.094
Domain overlap (PFAM):
C1:
PF134501=NAD_binding_8=PU(6.2=9.3)
A:
NA
C2:
PF134501=NAD_binding_8=FE(9.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains