HsaINT1044699 @ hg38
Intron Retention
Gene
ENSG00000160183 | TMPRSS3
Description
transmembrane protease, serine 3 [Source:HGNC Symbol;Acc:HGNC:11877]
Coordinates
chr21:42380117-42382234:-
Coord C1 exon
chr21:42382065-42382234
Coord A exon
chr21:42380213-42382064
Coord C2 exon
chr21:42380117-42380212
Length
1852 bp
Sequences
Splice sites
5' ss Seq
ATGGTACAT
5' ss Score
4.52
3' ss Seq
TATTGTTTCCCTTCAAGCAGAAA
3' ss Score
5.74
Exon sequences
Seq C1 exon
CTTGTACCTCCCCAAGTCATGGACCATCCAGGTGGGTCTAGTTTCCCTGTTGGACAATCCAGCCCCATCCCACTTGGTGGAGAAGATTGTCTACCACAGCAAGTACAAGCCAAAGAGGCTGGGCAATGACATCGCCCTTATGAAGCTGGCCGGGCCACTCACGTTCAATG
Seq A exon
GTACATCTGGGTCTCTATGTGGTTCTGCAGCTCTTCCTTTGTTTCAAGAGGATTTGCAATTGCTCATTGAAGCATTCTTATGATGGCTGCTTTATAATCCTTGTCAGATATTAATAATTCCAACTCCTGATTCATGTTGGTGTTGGCATCAGTTGATTATCTTTTCTCATTAAAATTGTGATGCTCCTAGCTCTTGGTATGACAAGTGATTTTCAATTGTATCCTGGACAATGTGGCTCTCATGTTTGCAGACTTGAGTCCTACCTACATTTTCAATGTTACCCTGTTTAAATGTAGTTTGTAGATCCTGGCCTACAGAATGAATGCACTGATGACTCTGCCAGGTAGATTGGTGGGCTGTAGTTCCAACAATAATTTTAGAGCCTTCGTGGGCTGTGTGCTTTGTCTGGTGCCACCTTCTCCCTGTTGGTGCCACCTTCTCCCTGTTGGTGCCACCTGGAGGCAGAAAGAGCTTCTTGAGGCCAGACCAGCTGGGGCCTCTAGGTGGTGGAAGAGAGTCATCCATCTGTAGGGACAAAGAGCACTTTCCTGTCCAGGAGCCTATTGTGGAGGGGTCACTCAGCCAGTGCCTCCCACCTGCCTGGTTTCTCCAGGTAGAGGGGCCATCTTGGTTGAGAAACAGAACCTCCCAGGCTGGCCAGGTGGTGTGGTGGAGTCCTCTCATTTCTTTACAAGCTGAAAGATGCTGGGCACCCTCAGCTCCCTGGAAGTACAGAAAAGTTCTCTCCCAACCAGCAGCTCCTAAAGACCCTGTTTCTTGAAAAAGTCAAGCCCTGCCCTCTGGACATTACGAAAATGCCAGAAGAGCCACACCTGATAAAACTTTCAAACATCTCGTAGATGCAAACAAAGTACTAGGAGACTACTCCCAATTAAATTAAAGCCCTCTTTCCTTCTTAAGAAAGCAGGGAAAGCATAATAAATAGGTTAATTCCCTCTTATTGAAGCAGAATCCTGACCTGAGACCAGCTGCAGGCTCTACCTGGCAGAGTCATTACTGCATCCATCACATGGACACGTAATGCCCAGAAACAAATATTTCCAGAGAAGCAGGAAAATGATTATGGTGGTGCCAGTCTGCCAACTATTATTAATGATATTGGTTATAGGAAATGAGGTGCCAGCACTTGTACTTTGCCAAAGTTTCAAGTGAGTTCTTTTATTCCTTCTCTACCTCTCCATTACTGTTCTGCACAGAAAAGCTCGGGGAACCTCAGGGTGTGTTCACACGAAAGCCCGAGGTATGTGCAGGGCACTCTGGCTTTGGGGGAGGCCCACAGGATCCAGCCCTACACACAGGCAAACTCGTCGCCTCCAGATATCCCAGGAACCATAGCAATATTCATGGAGCCGTGTTCTATAGGCAACACCCACACTGTGATCTAGCCAGGAGTGGGCACGCGTTGGCCTGAGAGCCTGGTCTGCCCCATCGTGTTTTGGTAAATAGACATTTTACTGGACACAGCCACACCTATGTGGGTACCTGTTACCTGGGGCTGTCTTCATGCTCCAATGGCAGCCAGAGACCGCACAGCCCACGAAGCCTACAACATTGACTATTCAGCCCTTTCCACAAAAGGTGTGCTGACCCTGGTCTAGGTTCCCTCACGCTGCGACGGTGGAGGGCTCTTTTACAGTTTTAAGTGCTCTGGGTGTGGTGGATGGGGTAAGGGGCTCCTGCTGTGAGCTGATCGTTTTCAAGTAACCAAGGGCTTGACCTTCCTTCCCTTGGGAGATAGTTTGGGCTCCTCAGAGGCAGAAGCATAGATGAGATTGTTTTCTCGGACTCCTGCTTCAATTGAGTTGTGAACTATTGTTTCCCTTCAAGCAG
Seq C2 exon
AAATGATCCAGCCTGTGTGCCTGCCCAACTCTGAAGAGAACTTCCCCGATGGAAAAGTGTGCTGGACGTCAGGATGGGGGGCCACAGAGGATGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160183:ENST00000291532:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(25.0=100)
A:
NA
C2:
PF0008921=Trypsin=FE(14.0=100)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGTACCTCCCCAAGTCATG
R:
CTCCATCCTCTGTGGCCCC
Band lengths:
266-2118
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains