HsaINT1045695 @ hg38
Intron Retention
Gene
ENSG00000196230 | TUBB
Description
tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778]
Coordinates
chr6:30722537-30723028:+
Coord C1 exon
chr6:30722537-30722645
Coord A exon
chr6:30722646-30722917
Coord C2 exon
chr6:30722918-30723028
Length
272 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
CTTAACTTTATTCTCTGTAGGTG
3' ss Score
9.49
Exon sequences
Seq C1 exon
TTCTGGGAGGTGATCAGTGATGAACATGGCATCGACCCCACCGGCACCTACCACGGGGACAGCGACCTGCAGCTGGACCGCATCTCTGTGTACTACAATGAAGCCACAG
Seq A exon
GTAAGGGCAGGAGCCCGGGCAGCTCAGGTTCCCTTCCCTGTCTCCCACTTATCTGGGATCTCTTTCCATTTCTGGGCACGCCTTATCCCCTTTGGGTGAATCTGTCATTTTGTCCCTTTCGTGAACCACCGTCGGGGCCAAAGACGTCTGCTGCCACCTGGTGGCGGGACCTGGAATGACAAGTCTCTGATCCCTGCTGTCTCCCATTTCCAGTATATCTATAAACCTTCCCTTCTGCCAGATTTCACAGCTCTTAACTTTATTCTCTGTAG
Seq C2 exon
GTGGCAAATATGTTCCTCGTGCCATCCTGGTGGATCTAGAACCTGGGACCATGGACTCTGTTCGCTCAGGTCCTTTTGGCCAGATCTTTAGACCAGACAACTTTGTATTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196230:ENST00000327892:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.122 A=NA C2=0.017
Domain overlap (PFAM):
C1:
PF0009120=Tubulin=FE(16.2=100)
A:
NA
C2:
PF0009120=Tubulin=PU(13.2=95.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTGGGAGGTGATCAGTGATGA
R:
AAGTTGTCTGGTCTAAAGATCTGGC
Band lengths:
212-484
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains