HsaINT1046278 @ hg38
Intron Retention
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133768442-133769503:-
Coord C1 exon
chr9:133769417-133769503
Coord A exon
chr9:133768597-133769416
Coord C2 exon
chr9:133768442-133768596
Length
820 bp
Sequences
Splice sites
5' ss Seq
CAGGTACCG
5' ss Score
10.05
3' ss Seq
CTGCCCATCTCCCTCAACAGTGT
3' ss Score
8.71
Exon sequences
Seq C1 exon
CTTCCTGTGCTTCCTACAACTTTTCTTTTCTCAGTCCTCAGGGCCTCAGCTTTGCTTCTCAGGGCCCCTCCGCTCCCTTCTGGTCAG
Seq A exon
GTACCGCTGCTCCCCAGGGCGTGGGGGGACCGGGCCTGTGGCAGCTGCCTTGGGAGACCCAGCACGGAGCTGCCCACTGGCCCCACAGCCCTGCCTGACGTGGCCACAGTTGTCCGCAGTCTGGCACTGGGTGGAGGGGAGAAAGGGGCTGGGGAGGCCGGGCAGAGGCTGCTGCGAGCACCTGAGGACACGTCAGGCTTGGCCCTGCCATTGTCACCACCCACCCCCTGTGGACACGCCCACCCTGATGGCCACTTTCCCAGCCCCGTCCACTGTCATTCCTCCTTGTTCATCAAGAGCTTTGCCTCTGGTAGCAGAAAGCAGGTGGCCACGAGGAGGAGCTGTGGGACTTGGGTGCAGGGAGGAGGGGTTTTCAGTCAGCCTTGACCTCATGGCTTTCGGCTGCCAGAGTCAAAGTCCCTTCCCAGCAGCTGTGTGTGTTTCGCCCTCAGCCATGGTCATTGTCACCTGTCTATCAGGATTCTGCATCTGGGCCAAGCTGGTTCCACTGGGTTTCTGGTTGGATTTGGGGGACCACTGGAATGATGATGGTCAAAGCCTGGGCACCTGCTCTTGTCCCTAAGAACATCCTCATTGCAGGGACTTGGATGTGCTGTGTCCCCAGACCCAGAGGGCAAGGGGCCCTGGGATTGGAGGCCAGTGTGTCCCTCCAGAGCCTTTCTGCTTGACATCCTTCCTCTCTGGGTACAGAGCAGGGTTCTGGGCACCAGGGGAGAGACCCAGCTTGGCCCAAGGGCCTCCTGGATCACTGGTTGGGCTCCTCCTGCAGCTGTGTGATGCTGCCCATCTCCCTCAACAG
Seq C2 exon
TGTTCACGCCCCGCGTCATCGGCACAGCTGTGGCCAGGTATAACTTTGCCGCCCGAGATATGAGGGAGCTTTCGCTGCGGGAGGGTGACGTGGTGAGGATCTACAGCCGCATCGGCGGAGACCAGGGCTGGTGGAAGGGCGAGACCAACGGACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293:ENST00000371850:28
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0765312=SH3_2=PU(76.4=80.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCCTGTGCTTCCTACAACT
R:
TCCGTTGGTCTCGCCCTTC
Band lengths:
239-1059
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains