Special

MmuEX0003018 @ mm9

Exon Skipping

Gene
ENSMUSG00000035722 | Abca7
Description
ATP-binding cassette, sub-family A (ABC1), member 7 [Source:MGI Symbol;Acc:MGI:1351646]
Coordinates
chr10:79477213-79478317:+
Coord C1 exon
chr10:79477213-79477305
Coord A exon
chr10:79477692-79477932
Coord C2 exon
chr10:79478051-79478317
Length
241 bp
Sequences
Splice sites
3' ss Seq
CCTGGTCCTGTCCCCTCCAGGTT
3' ss Score
11.34
5' ss Seq
GAGGTGACT
5' ss Score
5.88
Exon sequences
Seq C1 exon
CATGGAGGAGTGCGAAGCGCTCTGCACGCGCCTGGCCATCATGGTGAACGGGCGGTTCCGCTGTCTGGGAAGCTCTCAGCATCTCAAAGGCAG
Seq A exon
GTTCGGGGCTGGCCACACACTGACTCTAAGGGTCCCACCGGACCAGCCTGAGCCGGCGATAGCCTTCATCAGGATCACATTCCCTGGGGCTGAACTCCGGGAGGTGCACGGCAGCCGTCTGCGCTTCCAACTGCCACCGGGGGGCAGATGCACCCTGACACGAGTGTTCAGGGAGCTGGCTGCCCAGGGCAGGGCCCACGGTGTGGAGGACTTCTCTGTGAGCCAGACCACTCTGGAGGAG
Seq C2 exon
GTGTTCCTATATTTCTCCAAAGACCAAGGGGAAGAGGAAGAGAGCAGTCGGCAGGAGGCTGAAGAAGAGGAGGTTTCCAAACCTGGCCGGCAGCATCCCAAACGTGTCAGCCGATTCCTGGAAGACCCCAGCTCTGTGGAGACCATGATCTGAGCATGCCTGCCTTGGGACTGAGTGGCAAAGCTCAGACAGAGGATCTCTGTACCATACGCTGGCTCCCAGAAAGCCTTGGGCTCTGGGGGAAATAAAAAGAAACTAGAATGAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035722_CASSETTE5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (No Ref, Alt. Stop)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.111 C2=0.660
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000128121





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000043090, ENSMUSP00000115111
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr19:1064931-1065171 
HIGH PSI
HsaEX6091434
(ABCA7)
Human
(hg19)
chr19:1064930-1065170 
HIGH PSI
HsaEX6091434
(ABCA7)
Rat
(rn6)
chr7:12742786-12743026 
HIGH PSI
RnoEX0004922
(Abca7)
Cow
(bosTau6)
chr7:45181616-45181856 
HIGH PSI
BtaEX6040207
(ABCA7)
Chicken
(galGal4)
chr28:2823472-2823715 
HIGH PSI
GgaEX0003088
(ABCA7)
Chicken
(galGal3)
chr28:2377371-2377614 
HIGH PSI
GgaEX0003088
(ABCA7)
Zebrafish
(danRer10)
chr11:5709986-5710229 
HIGH PSI
DreEX6090508
(ABCA7)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGCCATCATGGTGAACGGG

				
R: 
TATTTCCCCCAGAGCCCAAGG

				
Band lengths: 
307-548

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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