Special

MmuEX0007410 @ mm9

Exon Skipping

Gene
ENSMUSG00000033488 | BC026585
Description
cDNA sequence BC026585 [Source:MGI Symbol;Acc:MGI:2448516]
Coordinates
chr1:159397297-159419191:+
Coord C1 exon
chr1:159397297-159397378
Coord A exon
chr1:159400747-159400928
Coord C2 exon
chr1:159418574-159419191
Length
182 bp
Sequences
Splice sites
3' ss Seq
ACCTTATGTTTTTCACTCAGGTC
3' ss Score
10.06
5' ss Seq
CAGGTGCGG
5' ss Score
9.13
Exon sequences
Seq C1 exon
AGAAACTGTTTTAGTGACAGCAGCTGCTGGAGCCACAGGCCTCGCAGTGATAGACGTGGCGACAAATGTGTTCCGCGCCAAG
Seq A exon
GTCATAGCTGCCACTGGAAGTGACGAGAAGTGCAAGCTGGCGGTGCAGAGGGGAGCACAGTTCAGTGTGAACTACAGCCAGGGCAGCCTGAGGGATGCAGTGAAGAAGCTGGCAGGCAGCGGTGGGGTCAACGTAGCCATTGACATGGTGGGAGGAGATGTCTTCCTGGAGTCTCTCCGCAG
Seq C2 exon
ATCAACGATGCCTTCCTTCATGTGATGCAGCGCAAATCCACGGGCAAGGTGCTCTTGTCCCTCAAGTAAACCCTACCCTGGGCAGACTCCCAAGTCTGCTGTCCCTCCTGCATTTTAAAGGGCTCATCCTTAGTGACCCAGGTGCCGTGTCTTGGTGTCAGTTCTCCTTGCTTCTGCTTTCTTGCTGCCTGTAATCATTGTGGCCACAGACATTCCTGCCTAAACTTAACCCCTTCTGTGAGCAAAAGGTACTGTGAGTTCCTTGAGAAATAGGTACTGTACTGGCTAGTTTTGTGTCAACTTGACACAGCTGGAGTTACCACAGAGAAAGGAGCTTCAGTTGAGGAAATGCCTCCATGAGATCCAGCTGTAAGGCATTTTCTTAATTAGTGATCAAGGGGGAAAGGTCCCTTGTGGGTGGGACCATCTCTGGGCTGGTAGTCTTGGTTCTATAAGAGAGCAAGCTGAGTAAGCCAGGGGAAGCAAGCCAGTAAAGAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033488_MULTIEX2-2/3=1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.033
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF082407=ADH_N=PD(7.3=32.1),PF0010721=ADH_zinc_N=PU(11.9=57.1)

							
A:
PF0010721=ADH_zinc_N=FE(44.4=100)

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000044945





     
                   









    
Main Skipping Isoform:
ENSMUSP00000113664





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr1:178026155-178026255 
HsaEX6035097
Human
(hg19)
chr1:177995290-177995390 
HIGH PSI
HsaEX6035097
(SEC16B)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr16:60853455-60853636 
HIGH PSI
BtaEX0001445
([1])
Chicken
(galGal4)
chr8:6589160-6589255 
Chicken
(galGal3)
chr8:6917586-6917767 
ALTERNATIVE
GgaEX0028954
([2])
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGACGTGGCGACAAATGTGTT

				
R: 
CAGGAATGTCTGTGGCCACAA

				
Band lengths: 
249-431

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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