Special

MmuEX0010726 @ mm9

Exon Skipping

Gene
ENSMUSG00000058579 | Cela2a
Description
chymotrypsin-like elastase family, member 2A [Source:MGI Symbol;Acc:MGI:95316]
Coordinates
chr4:141373780-141377376:-
Coord C1 exon
chr4:141377240-141377376
Coord A exon
chr4:141374897-141375042
Coord C2 exon
chr4:141373780-141373932
Length
146 bp
Sequences
Splice sites
3' ss Seq
CTCTCCGTGGTCTCATTCAGCCA
3' ss Score
6.29
5' ss Seq
AATGTGAGT
5' ss Score
7.8
Exon sequences
Seq C1 exon
CTATGACATTGCCTTAATCAAACTGGCCAGCCCAGTGACCCTGAGCAAGAACATCCAGACAGCTTGCCTCCCACCCGCTGGCACCATTCTCCCGAGAAACTATGTCTGCTATGTCACAGGCTGGGGCCTGCTGCAGA
Seq A exon
CCAATGGGAACAGTCCTGACACCCTGAGGCAGGGCCGCCTGCTGGTTGTGGACTATGCCACCTGCTCCAGCGCTAGCTGGTGGGGAAGCTCTGTGAAGTCCAGCATGGTGTGCGCTGGTGGCGACGGCGTGACCTCCAGCTGCAAT
Seq C2 exon
GGGGACTCTGGCGGACCACTGAATTGCCGGGCATCTAATGGCCAGTGGCAGGTGCATGGCATCGTGAGCTTCGGCTCCTCTCTGGGCTGCAACTACCCCCGCAAGCCATCCGTCTTCACCAGGGTCTCCAACTACATTGACTGGATCAACTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000058579-'6-7,'6-6,8-7
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0008921=Trypsin=FE(19.7=100)

							
A:
PF0008921=Trypsin=FE(20.5=100)

							
C2:
PF0008921=Trypsin=PD(20.5=94.1)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000099539





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr1:15812396-15812541 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr16:53277250-53277395 
BtaEX6069746
(ELA2A)
Chicken
(galGal4)
chr21:4925685-4925830 
HIGH PSI
GgaEX6024234
(CTRC)
Chicken
(galGal3)
chr21:4995319-4995464 
GgaEX6024234
(F1P457_CHICK)
Zebrafish
(danRer10)
chr5:25513802-25513834 
DreEX6010889
(ela3l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CCAGTGACCCTGAGCAAGAAC

				
R: 
TGTAGTTGGAGACCCTGGTGA

				
Band lengths: 
242-388

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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