MmuEX0011382 @ mm10
Exon Skipping
Gene
ENSMUSG00000041189 | Chrnb1
Description
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) [Source:MGI Symbol;Acc:MGI:87890]
Coordinates
chr11:69785707-69792908:-
Coord C1 exon
chr11:69792699-69792908
Coord A exon
chr11:69786881-69787104
Coord C2 exon
chr11:69785707-69785879
Length
224 bp
Sequences
Splice sites
3' ss Seq
CTGCCTTCACTGCCTCTCAGGAG
3' ss Score
7.14
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
Exon sequences
Seq C1 exon
AGAATGGCCAATGGGAGATTATCCACAAACCTTCTAGGTTAATCCAACTTCCAGGGGATCAGAGAGGTGGGAAGGAAGGGCATCATGAGGAAGTTATCTTCTATCTCATTATTCGGCGGAAGCCTCTCTTCTACCTGGTCAACGTCATTGCCCCATGCATCCTCATCACGCTCCTGGCCATCTTTGTCTTCTACCTCCCACCAGATGCAG
Seq A exon
GAGAGAAGATGGGGCTCTCCATCTTTGCCCTGCTGACGCTCACTGTGTTCTTGCTGCTGTTGGCCGACAAAGTGCCTGAGACCTCCCTGGCGGTGCCCATCATTATCAAGTACCTCATGTTTACCATGGTCCTTGTCACCTTCTCCGTTATCCTTAGTGTTGTGGTCCTCAACCTGCATCATCGCTCACCCCACACCCACCAAATGCCCTTTTGGGTCCGCCAG
Seq C2 exon
ATCTTCATTCACAAGCTCCCTCCATACCTGGGTCTGAAGAGGCCCAAACCCGAGAGAGACCAACTCCCTGAACCACATCACTCTCTTTCTCCAAGAAGTGGCTGGGGCAGAGGAACTGATGAATATTTCATCCGGAAGCCTCCAAGTGATTTTCTTTTCCCTAAACTTAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041189_MULTIEX2-2/2=1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=0.000 C2=0.276
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=PD(18.7=57.7),PF0293211=Neur_chan_memb=PU(9.3=31.0)
A:
PF0293211=Neur_chan_memb=FE(31.4=100)
C2:
PF0293211=Neur_chan_memb=FE(24.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCCAACTTCCAGGGGATCAGA
R:
TTCATCAGTTCCTCTGCCCCA
Band lengths:
292-516
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types