Special

MmuEX0011466 @ mm9

Exon Skipping

Gene
ENSMUSG00000039205 | Ciz1
Description
CDKN1A interacting zinc finger protein 1 [Source:MGI Symbol;Acc:MGI:1920234]
Coordinates
chr2:32225762-32228015:+
Coord C1 exon
chr2:32225762-32225864
Coord A exon
chr2:32227156-32227277
Coord C2 exon
chr2:32227818-32228015
Length
122 bp
Sequences
Splice sites
3' ss Seq
GAACGTATATGTCATTTCAGACC
3' ss Score
4.84
5' ss Seq
GGGGTGCGT
5' ss Score
5.27
Exon sequences
Seq C1 exon
ACCAAGATTCACTAGTCGGTCCAGATAGCATGCTGAGTGAGCCCCAAGTGCCTGAGCCTGAGCCCTTTGAGACATTGGAACCACCAGCCAAGAGGTGCAGGAG
Seq A exon
ACCCAGACAAGGCCTTGCCAGAACCAGTAAGTGCCCAGAGCAGTGAAGACAGGAGCCGGGAGGCGTCCGCTGGTGGCCTGGATTTGGGAGAATGTGAAAAGAGAGCGGGAGAGATGCTGGGG
Seq C2 exon
ATGTGGGGGGCTGGGAGCTCCCTGAAGGTCACCATCCTGCAGAGTAGCAACAGCCGGGCCTTTAACACCACACCCCTCACATCTGGACCTCGCCCTGGGGACTCTACCTCTGCCACCCCTGCCATTGCCAGCACACCCTCCAAGCAAAGCCTCCAGTTCTTCTGCTACATCTGCAAGGCCAGCAGCAGCAGCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039205_MULTIEX2-3/3=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=1.000 A=1.000 C2=0.502
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF127562=zf-C2H2_2=PU(50.0=39.4),PF049887=AKAP95=PU(23.2=19.7)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000048428





     
                   









    
Main Skipping Isoform:
ENSMUSP00000122469





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000048428f3938A, ENSMUSP00000048974, ENSMUSP00000108957, ENSMUSP00000108958, ENSMUSP00000108960, ENSMUSP00000108962, ENSMUSP00000108964, ENSMUSP00000119429, ENSMUSP00000120019
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:128178369-128178490 
ALTERNATIVE
HsaEX0015440
(CIZ1)
Human
(hg19)
chr9:130940648-130940769 
HIGH PSI
HsaEX0015440
(CIZ1)
Rat
(rn6)
chr3:11401013-11401134 
HIGH PSI
RnoEX0021394
(Ciz1)
Cow
(bosTau6)
chr11:98814628-98814749 
HIGH PSI
BtaEX6046345
(CIZ1)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TCGGTCCAGATAGCATGCTGA

				
R: 
AACTGGAGGCTTTGCTTGGAG

				
Band lengths: 
246-368

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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