MmuEX0014213 @ mm10
Exon Skipping
Gene
ENSMUSG00000035392 | Dennd1a
Description
DENN/MADD domain containing 1A [Source:MGI Symbol;Acc:MGI:2442794]
Coordinates
chr2:38159807-38287375:-
Coord C1 exon
chr2:38287113-38287375
Coord A exon
chr2:38243402-38243472
Coord C2 exon
chr2:38159807-38159850
Length
71 bp
Sequences
Splice sites
3' ss Seq
ATGATATGTTTCCTTTGTAGGCA
3' ss Score
10.27
5' ss Seq
CAGGTACTC
5' ss Score
7.04
Exon sequences
Seq C1 exon
GCGCCGGGTACGCGCGCGGGCGACCATGGCGCTCGCCCGGCTGGAGCGAGTACTTTAACCCCGGGAGGCGACAGCAGCTGCGGCGGCCGGGGAGCGAGCCTCGAGCGGGCGGGCCCCTGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCTCCTGAGGGAGGCCTGTCGGCCGCGGGCGGGCGGGCAGTGCAGTGCAGCGCAGCACCGAGCGGGGCCCGCGGGTCCATGAGGAGGCCCCGGGACCATGGGCTCCAGGATCAA
Seq A exon
GCAAAACCCAGAGACTACATTTGAAGTGTATGTGGAAGTGGCTTATCCTAGGACAGGTGGCACTCTTTCAG
Seq C2 exon
ATCCTGAGGTGCAGAGGCAATTCCCAGAGGACTACAGTGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035392-'0-17,'0-4,11-17
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.480 A=0.092 C2=0.200
Domain overlap (PFAM):
C1:
NO
A:
PF0345613=uDENN=PU(0.1=0.0)
C2:
PF0345613=uDENN=PU(23.0=93.3)
Main Skipping Isoform:
ENSMUST00000102787fB8661
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAGGGAAGGGAGGAAGGG
R:
AGTCCTCTGGGAATTGCCTCT
Band lengths:
176-247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types