Special

MmuEX0014215 @ mm9

Exon Skipping

Gene
Description
DENN/MADD domain containing 1A [Source:MGI Symbol;Acc:MGI:2442794]
Coordinates
chr2:37817161-37858994:-
Coord C1 exon
chr2:37858894-37858994
Coord A exon
chr2:37838580-37838625
Coord C2 exon
chr2:37817161-37817262
Length
46 bp
Sequences
Splice sites
3' ss Seq
GTCTCTGTTTCTCTTCACAGTGC
3' ss Score
11.37
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
TTGACGGCCTGCATCCACGGCTCAGCTGCCATGCTCTACCCTATGTACTGGCAGCATGTGTACATCCCTGTGCTGCCCCCACATCTGCTGGACTACTGCTG
Seq A exon
TGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAG
Seq C2 exon
AAGGTCAGGAACATGGCCCTCGATGATGTTGTGATCTTGAACGTGGACACCAACACCCTGGAAACCCCTTTTGATGACCTCCAGAGCCTCCCAAATGATGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035392_MULTIEX2-11/12=10-12
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.024
Domain overlap (PFAM):

C1:
PF0214116=DENN=FE(18.3=100)
A:
PF0214116=DENN=FE(8.3=100)
C2:
PF0214116=DENN=PD(9.4=50.0)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTGCCATGCTCTACCCTAT
R:
GGTGTTGGTGTCCACGTTCAA
Band lengths:
135-181
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types