Special

MmuEX0014955 @ mm9

Exon Skipping

Gene
ENSMUSG00000018581 | Dnahc11
Description
dynein, axonemal, heavy chain 11 [Source:MGI Symbol;Acc:MGI:1100864]
Coordinates
chr12:119199458-119210889:-
Coord C1 exon
chr12:119210788-119210889
Coord A exon
chr12:119205005-119205139
Coord C2 exon
chr12:119199458-119199628
Length
135 bp
Sequences
Splice sites
3' ss Seq
ATTTTGACTCCTCCTTTTAGGAT
3' ss Score
11.11
5' ss Seq
GAGGCAAGT
5' ss Score
3.32
Exon sequences
Seq C1 exon
GTTTATTGTGATGTGGAGCCCAAACGCCAGGCATTGGCCCAAACAAACTTGGACCTGGCTGCAGCTACTGAAAAGCTAGAGGCTGTAAGGAGGAAACTTGTG
Seq A exon
GATCTGGATCATAATCTGAGCAGACTTACAGCTTCATTTGAAAAGGCAACAGCTGAGAAGGTCCGGTGTCAGGAAGAAGTGAATCAAACCAATAAGACGATCGACCTAGCCAACAAACTTGTCAGTGAACTTGAG
Seq C2 exon
TCAGAGAAGATTCGATGGGGTCAGTCCATTAAGTCCTTTGAAACTCAAGAGAAGACACTGTGTGGAGATGTGCTCCTCACGGCGGCATTTGTGTCTTACATTGGGTCCTTCACAAGACAGTATCGCCAGGAACTGGTGGACTGCAAGTGGATTCCATTTCTTCAGCAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018581-'63-62,'63-61,64-62
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127772=MT=FE(9.6=100),PF060097=Laminin_II=PU(21.8=55.9)

							
A:
PF127772=MT=FE(12.8=100),PF060097=Laminin_II=FE(50.6=100)

							
C2:
PF127772=MT=PD(15.4=93.0),PF060097=Laminin_II=PD(24.1=36.8)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000081867





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000081867f560A, ENSMUSP00000135748
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr7:21801137-21801271 
HsaEX6007383
(DNAH11)
Human
(hg19)
chr7:21840755-21840893 
HIGH PSI
HsaEX6007383
(DNAH11)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr4:30683647-30683781 
HIGH PSI
BtaEX6026602
(DNAH11)
Chicken
(galGal4)
chr2:30652247-30652387 
Chicken
(galGal3)
chr2:30549395-30549531 
Zebrafish
(danRer10)
chr16:19423332-19423466 
DreEX6040413
(DNAH11)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TTGTGATGTGGAGCCCAAACG

				
R: 
CTTGCAGTCCACCAGTTCCTG

				
Band lengths: 
244-379

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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