Special

MmuEX0014959 @ mm9

Exon Skipping

Gene
ENSMUSG00000018581 | Dnahc11
Description
dynein, axonemal, heavy chain 11 [Source:MGI Symbol;Acc:MGI:1100864]
Coordinates
chr12:119149491-119154080:-
Coord C1 exon
chr12:119153932-119154080
Coord A exon
chr12:119152979-119153106
Coord C2 exon
chr12:119149491-119149718
Length
128 bp
Sequences
Splice sites
3' ss Seq
CACCCCCAATTCTCCAACAGGCA
3' ss Score
8.49
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GAATTTCGTAGAAGAGAAACTAGGAGCAAAGTATGTGGAGAGGACTAGATTGGACCTGGGCAAAGCATTTGAAGAAAGCAGCCCGAGCACCCCGGTGTTCTTCATCCTGTCTCCAGGTGTGGATGCCCTTAAAGACTTAGAGGTGCTCG
Seq A exon
GCAAAAGGCTGGGGTTTACGATTGACTCTGGAAAATTCCACAATGTGTCTCTAGGGCAAGGTCAGGAACTAGTGGCGGAAATGGCAATGGAGAAAGCTGCCGCTGGAGGACACTGGGTCATCCTTCAG
Seq C2 exon
AATGTTCATCTGGTAGCCAAATGGCTGGGAACTCTGGAGAAACTCCTTGAAAAATTCAGTCAAGGAAGCCACAGAGATTACAGGGTGTTCCTGAGTGCTGAGACTGTACCTTCCCAACATGAGCCCATAATCCCTCAAGGCCTCCTGGAAAATTCCATTAAGATCACTAACGAGCCCCCCACGGGAATGCTGGCCAACCTACATGCTGCTTTGTACAACTTTGACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018581-'75-76,'75-74,76-76
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0302810=Dynein_heavy=FE(7.1=100)

							
A:
PF0302810=Dynein_heavy=FE(6.0=100)

							
C2:
PF0302810=Dynein_heavy=FE(10.7=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000081867





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:21868864-21868991 
ALTERNATIVE
HsaEX6007372
(DNAH11)
Human
(hg19)
chr7:21908482-21908609 
HIGH PSI
HsaEX6007372
(DNAH11)
Rat
(rn6)
chr6:145816730-145816857 
HIGH PSI
RnoEX6030098
(Dnah11)
Cow
(bosTau6)
chr4:30760225-30760352 
HIGH PSI
BtaEX6026591
(DNAH11)
Chicken
(galGal4)
chr2:30671726-30671845 
ALTERNATIVE
GgaEX1002507
([1])
Chicken
(galGal3)
chr2:30568874-30568993 
Zebrafish
(danRer10)
chr16:19399422-19399549 
HIGH PSI
DreEX6040424
(DNAH11)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGGACTAGATTGGACCTGGGC

				
R: 
CCAGGAGGCCTTGAGGGATTA

				
Band lengths: 
257-385

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"