Special

MmuEX0014973 @ mm9

Exon Skipping

Gene
ENSMUSG00000033987 | Dnahc17
Description
dynein, axonemal, heavy chain 17 [Source:MGI Symbol;Acc:MGI:1917176]
Coordinates
chr11:117934159-117935376:-
Coord C1 exon
chr11:117935203-117935376
Coord A exon
chr11:117934830-117935037
Coord C2 exon
chr11:117934159-117934324
Length
208 bp
Sequences
Splice sites
3' ss Seq
CATCCTGCTACGGCCCCCAGGCC
3' ss Score
6.28
5' ss Seq
AGGGTGAGA
5' ss Score
6.65
Exon sequences
Seq C1 exon
CTCATTGATTATCGAGTGGAGTTCAGCAAGTGGTGGATCAATGAATTTAAAACAATCAAGTTACCCTCGCAGGGGACCATTTTTGACTACTACATTGACCCTGAAACAAAAAAATTCCTGCCTTGGACAGATAAAGTGCCTAACTTTGAGCTGGATCCCGACATCCCACTACAG
Seq A exon
GCCTCTCTAGTCCACACCACAGAAACCATCCGCATCCGGTACTTCATAGACCTGCTCATGGAGAAGGCATGGCCCGTGATGCTGGTGGGCAACGCGGGCACTGGCAAGTCGGTGCTGATGGGTGACAAGCTGGAGAACCTCAGCACCGACGACTACCTGGTGCAGGCCGTGCCTTTCAACTTCTACACGACCTCAGCCATGCTGCAGG
Seq C2 exon
GGGTGCTGGAGAAGCCTCTGGAAAAGAAGTCAGGGAGGAACTACGGCCCCCCAGGCACTAAGAAGCTGATCTACTTCATCGATGACATGAACATGCCAGAGGTGGACAAGTATGGCACGGTGGCCCCACACACCCTCATCCGCCAGCACATGGACCACAGGCACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033987-'54-52,'54-51,55-52
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.089
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127752=AAA_7=PU(3.3=15.5)

							
A:
PF127752=AAA_7=FE(25.4=100)

							
C2:
PF127752=AAA_7=FE(20.2=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000101915





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000047129, ENSMUSP00000081864, ENSMUSP00000120542
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:78485550-78485757 
HIGH PSI
HsaEX6025151
(DNAH17)
Human
(hg19)
chr17:76481632-76481839 
HIGH PSI
HsaEX6025151
(DNAH17)
Rat
(rn6)
chr10:107083037-107083244 
ALTERNATIVE
RnoEX0028482
(Dnah17)
Cow
(bosTau6)
chr19:54367669-54367876 
HIGH PSI
BtaEX6090378
(DNAH17)
Chicken
(galGal4)
chr18:10085504-10085711 
HIGH PSI
GgaEX7009569
(DNAH17)
Chicken
(galGal3)
chr18:9757243-9757450 
Zebrafish
(danRer10)
chr6:10404358-10404562 
DreEX6020683
(dnah9l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CGAGTGGAGTTCAGCAAGTGG

				
R: 
CTGGCGGATGAGGGTGTGT

				
Band lengths: 
308-516

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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