Special

MmuEX0015007 @ mm9

Exon Skipping

Gene
ENSMUSG00000052861 | Dnahc6
Description
dynein, axonemal, heavy chain 6 [Source:MGI Symbol;Acc:MGI:107744]
Coordinates
chr6:73067996-73071995:-
Coord C1 exon
chr6:73071774-73071995
Coord A exon
chr6:73070529-73070676
Coord C2 exon
chr6:73067996-73068153
Length
148 bp
Sequences
Splice sites
3' ss Seq
TCTTTTTTTTTTATTCAAAGTCC
3' ss Score
6.66
5' ss Seq
TAGGTGAGC
5' ss Score
7.96
Exon sequences
Seq C1 exon
CTTCCCAGCTCTGGAGATCTGTGGAGCATTCATATAGACTTTGACACCAAACGCCTGGACCCCTGGGAGCGCATTATACCCACCTTCAAGTACAGCAGGGATGTCCCATTCTTTGAGATGCTTGTCCCCACAACAGACACAGTGCGCTATGGCTATCTAATGGAAAAGCTGCTGGCCGTCAGGCATTCGGTGTTGTTTACGGGAACAACTGGCGTTGGCAAG
Seq A exon
TCCGTTATTGCAAAAGGATTGCTGAATAGAATTCAAGAATCAGCTGGCTATGTCCCTGTTTATCTAAATTTTTCTGCCCAAACTTCATCTTCAAGGACACAGGAGATCATTGAGTCAAAACTGGAACGAAAGAGAAAAAATATTCTAG
Seq C2 exon
GAGCACCAGGAAATAAACAAGTGGTGATTTTTGTTGATGATCTGAATATGCCCCGGCTGGACCGCTATGGCTCCCAACCACCAATTGAACTGCTTCGGCAGTATCAAGATTTTGGTGGATTCTATGATAGAAACAAACTCTTTTGGAAAGAAATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000052861-'39-39,'39-38,40-39
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.060 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127752=AAA_7=PU(16.5=60.8)

							
A:
PF127752=AAA_7=FE(18.0=100)

							
C2:
PF127752=AAA_7=FE(19.1=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000068758





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000109672, ENSMUSP00000109674
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:84670328-84670475 
HIGH PSI
HsaEX6014182
(DNAH6)
Human
(hg19)
chr2:84897452-84897599 
HIGH PSI
HsaEX6014182
(DNAH6)
Rat
(rn6)
chr4:101039912-101040059 
HIGH PSI
RnoEX6013930
(Dnah6)
Cow
(bosTau6)
chr11:50186326-50186473 
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr1:21383966-21384113 
HIGH PSI
DreEX6031366
(dnah7l)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTGGGAGCGCATTATACCCAC

				
R: 
TTCAATTGGTGGTTGGGAGCC

				
Band lengths: 
249-397

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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