Special

MmuEX0015026 @ mm9

Exon Skipping

Gene
ENSMUSG00000041144 | Dnahc7c
Description
dynein, axonemal, heavy chain 7B [Source:MGI Symbol;Acc:MGI:2684953]
Coordinates
chr1:46310215-46333996:+
Coord C1 exon
chr1:46310215-46310378
Coord A exon
chr1:46325450-46325604
Coord C2 exon
chr1:46333806-46333996
Length
155 bp
Sequences
Splice sites
3' ss Seq
TTATCTCTTCTCTGTTTCAGGAA
3' ss Score
12.69
5' ss Seq
CTGGTATGT
5' ss Score
8.14
Exon sequences
Seq C1 exon
AATCAAACCCAGGAGTGGTCACAGTCGTGTAAAGAAAGAGACATCCCCTGCTCTGATGACTACTCTCTTATGGGCACACTGGGAGAGGCCGTGACGATTCGAGCTTGGAATATCGCTGGGTTACCCTCTGACTCTTTCTCCATTGATAATGGGATCATTATAAT
Seq A exon
GAATGCAAGAAGGTGGCCTCTGATGATAGACCCTCAAGGTCAGGCTAATAAGTGGATCAAGAACATGGAGAAAACCAATAGCCTTCAGCTCATTAAACTAAGTGACCCTGACTATGTCAGAACTCTGGAAAACTGTATCCAGTTTGGAACTCCTG
Seq C2 exon
TGTTGCTAGAAAATGTGGGAGAAGAACTGGACCCAATTCTAGAGCCTCTTTTGTTGAAGCAGACCTTCAAGCAGGGTGGGAGCACATGCATTCGGCTTGGAGACTCCACAATTGAGTATGCTCCCGACTTCCGCTTCTACATCACAACCAAGCTGAGGAACCCGCACTATCTCCCAGAGACGTCAGTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041144-'51-49,'51-47,52-49
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.055 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127772=MT=PD(2.0=12.7),PF127812=AAA_9=PU(12.6=52.7)

							
A:
PF127812=AAA_9=FE(22.5=100)

							
C2:
PF127812=AAA_9=FE(27.3=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000068738





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000068738f4197A, ENSMUSP00000068738f4198A, ENSMUSP00000068738f5803A, ENSMUSP00000068738f5806A
          









    
Other Skipping Isoforms:
NA
  



Associated events






Conservation


Human
(hg38)
chr2:195834206-195834360 
ALTERNATIVE
HsaEX0020209
(DNAH7)
Human
(hg19)
chr2:196698930-196699084 
ALTERNATIVE
HsaEX0020209
(DNAH7)
Rat
(rn6)
chr9:60164485-60164639 
HIGH PSI
RnoEX6039700
(Dnah7)
Cow
(bosTau6)
chr2:84841179-84841333 
HIGH PSI
BtaEX6010450
(DNAH7)
Chicken
(galGal4)
chr7:9205661-9205815 
HIGH PSI
GgaEX6041829
(DNAH7)
Chicken
(galGal3)
chr7:10694993-10695147 
HIGH PSI
GgaEX6041829
(DNAH7)
Zebrafish
(danRer10)
chr9:25172277-25172431 
HIGH PSI
DreEX6036423
(dnah7)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CGTGACGATTCGAGCTTGGAA

				
R: 
GGAGATAGTGCGGGTTCCTCA

				
Band lengths: 
249-404

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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