Special

MmuEX0015049 @ mm9

Exon Skipping

Gene
ENSMUSG00000041144 | Dnahc7c
Description
dynein, axonemal, heavy chain 7B [Source:MGI Symbol;Acc:MGI:2684953]
Coordinates
chr1:46232132-46239326:+
Coord C1 exon
chr1:46232132-46232325
Coord A exon
chr1:46234075-46234273
Coord C2 exon
chr1:46239186-46239326
Length
199 bp
Sequences
Splice sites
3' ss Seq
TTTAATTTTTTTTCCAACAGAGT
3' ss Score
9.71
5' ss Seq
AAGGTAATT
5' ss Score
8.83
Exon sequences
Seq C1 exon
GATAAGCGAGTCCTGGCAGTCGTGACTATCGAGCGGATGCTGGAGAGGCTGAAAAAGTCCAACGAACTCTTGGAGCTCATTCTTAAAGGGTTGAATGAGTACTTGGAAAAGAAGCGCCTCTTCTTCCCCAGGTTCTTCTTCCTGTCCAACGATGAGCTCCTCGAGATCCTGTCTGAGACCAAGGATCCCACCCG
Seq A exon
AGTGCAGCCTCACCTCAAGAAATGCTTTGAAGGAATTGCAAAGGTCGAATTTACAGAAACTTTGGATATTACACATATGAAGAGTAGTGAGGGAGAAGTCGTGGAGCTTGTAGATACCATTTCAACAGCCAAAGCCAGGGGCCAGGTGGAGAAGTGGTTGGTTGAGTTAGAGAGGACTATGATTAAGTCCATTCACAAG
Seq C2 exon
GTGATTGGAGATGCAATTGCTGCCTATACCAAAAATTCACGAATTAGTTGGGTAAGAGATTGGCCTGGACAGACTGTTCTCTGTGTATCTCAAACCTTTTGGACAGTAGAAGTCCAAACTGCTATACCTAAGGGGCATAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000041144-'21-21,'21-20,22-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF083938=DHC_N2=FE(15.5=100)

							
A:
PF083938=DHC_N2=PD(18.4=66.7)

							
C2:
PF083938=DHC_N2=PD(2.2=19.1)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000068738





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000068738f4197A, ENSMUSP00000068738f4198A, ENSMUSP00000068738f5803A, ENSMUSP00000068738f5805A, ENSMUSP00000068738f5806A, ENSMUSP00000068738f5807A
          









    
Other Skipping Isoforms:
NA
  



Associated events






Conservation


Human
(hg38)
chr2:195934591-195934789 
ALTERNATIVE
HsaEX6017563
(DNAH7)
Human
(hg19)
chr2:196799315-196799513 
ALTERNATIVE
HsaEX6017563
(DNAH7)
Rat
(rn6)
chr9:60280764-60280962 
HIGH PSI
RnoEX6039688
(Dnah7)
Cow
(bosTau6)
chr2:84938243-84938441 
HIGH PSI
BtaEX6010427
(DNAH7)
Chicken
(galGal4)
chr7:9247016-9247214 
HIGH PSI
GgaEX6041811
(DNAH7)
Chicken
(galGal3)
chr7:10737830-10738028 
HIGH PSI
GgaEX6041811
(DNAH7)
Zebrafish
(danRer10)
chr9:25218782-25218980 
HIGH PSI
DreEX0027473
(dnah7)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
AGTCGTGACTATCGAGCGGAT

				
R: 
ACAGTCTGTCCAGGCCAATCT

				
Band lengths: 
254-453

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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