Special

MmuEX0016916 @ mm9

Exon Skipping

Gene
ENSMUSG00000015085 | Entpd2
Description
ectonucleoside triphosphate diphosphohydrolase 2 [Source:MGI Symbol;Acc:MGI:1096863]
Coordinates
chr2:25253521-25254279:+
Coord C1 exon
chr2:25253521-25253671
Coord A exon
chr2:25253811-25253970
Coord C2 exon
chr2:25254052-25254279
Length
160 bp
Sequences
Splice sites
3' ss Seq
CCCCCTCCCCCATTCCACAGCCT
3' ss Score
10.35
5' ss Seq
AAGGTGGGC
5' ss Score
7.93
Exon sequences
Seq C1 exon
GTGGTGGCATCTCCAGCTACGCAAATGACCCTTCTAGGGCAGGCCAGAGTCTGGTTGAATGTCTTGAACAGGCACTTCGGGATGTGCCCAAAGACAGATATGCCAGCACTCCACTCTACCTGGGAGCTACAGCAGGCATGCGCCTACTCAA
Seq A exon
CCTGACCAGCCCAGAGGCCACAGCCAAGGTGCTGGAGGCAGTGACACAGACGCTCACACGGTACCCCTTTGACTTCCGTGGTGCCCGCATCCTCTCGGGACAGGATGAAGGGGTGTTTGGCTGGGTGACTGCCAACTACCTGCTGGAGAACTTCATCAAG
Seq C2 exon
TATGGCTGGGTAGGCCGGTGGATACGGCCAAGGAAGGGAACTCTGGGGGCCATGGACCTTGGGGGTGCCTCAACACAGATCACCTTTGAGACAACCAGTCCATCTGAAGATCCAGATAATGAGGTCCATTTGCGGCTCTATGGCCAGCATTACCGTGTCTACACCCATAGCTTCCTCTGCTATGGCCGGGACCAGGTTCTCCAGAGGCTTCTGGCCAGTGCCCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015085_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.113
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0115012=GDA1_CD39=FE(11.7=100)

							
A:
PF0115012=GDA1_CD39=FE(12.4=100)

							
C2:
PF0115012=GDA1_CD39=FE(17.6=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000028328





     
                   









    
Main Skipping Isoform:
ENSMUSP00000109926





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:137051211-137051370 
HIGH PSI
HsaEX0022529
(ENTPD2)
Human
(hg19)
chr9:139945663-139945822 
HIGH PSI
HsaEX0022529
(ENTPD2)
Rat
(rn6)
chr3:2620209-2620368 
HIGH PSI
RnoEX0032234
(Entpd2)
Cow
(bosTau6)
chr11:106186108-106186267 
HIGH PSI
BtaEX6047591
(ENTPD2)
Chicken
(galGal4)
chr17:406513-406672 
HIGH PSI
GgaEX6014652
(ENTPD2)
Chicken
(galGal3)
chr17:1312140-1312278 
Zebrafish
(danRer10)
chr5:28967128-28967287 
HIGH PSI
DreEX6011335
(entpd2a.2)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TTGAACAGGCACTTCGGGATG

				
R: 
GTAGACACGGTAATGCTGGCC

				
Band lengths: 
250-410

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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