Special

MmuEX0018611 @ mm10

Exon Skipping

Description
fibroblast activation protein [Source:MGI Symbol;Acc:MGI:109608]
Coordinates
chr2:62503365-62512440:-
Coord C1 exon
chr2:62512386-62512440
Coord A exon
chr2:62504506-62504605
Coord C2 exon
chr2:62503365-62503429
Length
100 bp
Sequences
Splice sites
3' ss Seq
CAATAACAATGTCTCTACAGTCC
3' ss Score
4.68
5' ss Seq
ACGGTATGG
5' ss Score
8.47
Exon sequences
Seq C1 exon
AAAATTCATAGAAATGGGTTTCATTGATGAAGAAAGAATAGCCATATGGGGCTGG
Seq A exon
TCCTACGGAGGTTATGTTTCATCCCTGGCCCTTGCATCTGGAACTGGTCTTTTCAAATGTGGCATAGCAGTGGCTCCAGTCTCCAGCTGGGAATATTACG
Seq C2 exon
CATCTATCTACTCAGAGAGATTCATGGGCCTCCCAACAAAGGACGACAATCTCGAACACTATAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000392-'31-29,'31-27,32-29
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
PF0032616=Peptidase_S9=FE(16.4=100)
A:
PF0032616=Peptidase_S9=FE(15.9=100)
C2:
PF0032616=Peptidase_S9=PU(40.4=95.0)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
(FAP)
Chicken
(galGal3)
HIGH PSI
(FAP)
Zebrafish
(danRer10)
HIGH PSI
(fap)
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATAGAAATGGGTTTCATTGATGAA
R:
TTGTCGTCCTTTGTTGGGAGG
Band lengths:
99-199
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types